TWAS
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Traits
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Vascular/heart problems diagnosed by doctor
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chr6:57,608,708-58,770,624
Best TWAS P=1.81e-07 · Best GWAS P=5.33e-07 conditioned to 0.0087
57.6M
57.8M
58M
58.2M
58.4M
58.6M
58.8M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Hippocampus
LINC00680
0.5
0.22
lasso
6
0.42
7e-11
-3.1
-5.2
1.8e-07
-0.54
0.12
0.73
TRUE