Best TWAS P=2.49e-12 · Best GWAS P=4.12e-14 conditioned to 0.00228
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HOXA10 | 0.02 | 0.01 | blup | 53 | 0.01 | 0.00903 | 7.39 | -7.0 | 2.5e-12 | -0.85 | 0.00 | 0.85 | TRUE |
2 | The Cancer Genome Atlas | Esophageal Carcinoma | EVX1 | 0.16 | 0.02 | blup | 50 | 0.12 | 0.00014 | -0.62 | 5.9 | 4.4e-09 | 0.74 | 0.01 | 0.40 | FALSE |