TWAS
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Models
Genes
Traits
[Hub]/) :
Traits
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Vascular/heart problems diagnosed by doctor
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chr7:26,969,253-27,533,292
Best TWAS P=2.49e-12 · Best GWAS P=4.12e-14 conditioned to 0.00228
27M
27.1M
27.2M
27.3M
27.4M
27.5M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
HOXA10
0.02
0.01
blup
53
0.01
0.00903
7.39
-7.0
2.5e-12
-0.85
0.00
0.85
TRUE
2
The Cancer Genome Atlas
Esophageal Carcinoma
EVX1
0.16
0.02
blup
50
0.12
0.00014
-0.62
5.9
4.4e-09
0.74
0.01
0.40
FALSE