[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr7:73,425,238-75,255,633

Best TWAS P=8.18e-09 · Best GWAS P=1.61e-08 conditioned to 0.0428

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	GTEx	Nerve Tibial	STAG3L2	0.36	0.09	enet	13	0.24	9.5e-17	-3.8	5.8	8.2e-09	-0.75	0.04	0.96	TRUE
6	GTEx	Esophagus Mucosa	PMS2P5	0.14	0.03	lasso	4	0.04	1.7e-03	-5.4	5.8	8.9e-09	-0.78	0.02	0.78	FALSE
5	GTEx	Esophagus Gastroesophageal Junction	PMS2P5	0.23	0.19	lasso	2	0.18	5.4e-07	-5.4	5.7	1.0e-08	-0.75	0.02	0.96	FALSE
13	GTEx	Thyroid	GTF2IRD2B	0.03	0.04	lasso	1	0.03	1.9e-03	-5.6	-5.7	1.6e-08	1.00	0.01	0.86	FALSE
11	GTEx	Skin Sun Exposed Lower leg	STAG3L2	0.15	0.05	enet	8	0.08	2.8e-07	-3.8	5.6	2.6e-08	-0.72	0.12	0.72	FALSE
7	GTEx	Esophagus Muscularis	STAG3L2	0.23	0.09	enet	33	0.15	1.9e-09	-3.8	5.5	3.3e-08	-0.77	0.03	0.97	FALSE
8	GTEx	Heart Atrial Appendage	PMS2P5	0.12	0.03	lasso	5	0.07	3.8e-04	-5.4	5.5	4.5e-08	-0.73	0.02	0.42	FALSE
1	GTEx	Adipose Subcutaneous	STAG3L2	0.16	0.03	enet	11	0.09	1.0e-07	-3.8	5.4	6.8e-08	-0.70	0.09	0.89	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	PMS2P5	0.16	0.06	lasso	3	0.04	1.7e-02	-5.4	5.3	8.7e-08	-0.81	0.01	0.76	FALSE
2	GTEx	Adipose Subcutaneous	AC004166.6	0.09	0.08	lasso	2	0.07	3.9e-06	-5.4	-5.3	1.1e-07	0.84	0.02	0.97	FALSE
14	METSIM	Adipose	NCF1	0.05	0.03	blup	130	0.04	3.9e-07	-5.5	-5.3	1.1e-07	0.70	0.01	0.99	FALSE
12	GTEx	Testis	PMS2P5	0.22	0.13	lasso	2	0.13	3.1e-06	-5.4	5.2	1.7e-07	-0.73	0.02	0.90	FALSE
3	GTEx	Adrenal Gland	STAG3L2	0.14	0.07	enet	3	0.11	1.2e-04	-4.9	5.2	2.3e-07	-0.90	0.03	0.71	FALSE
9	GTEx	Nerve Tibial	PMS2P5	0.16	0.04	enet	34	0.08	3.5e-06	-3.8	5.1	2.9e-07	-0.67	0.02	0.96	FALSE