[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr7:73,425,238-75,255,633

Best TWAS P=8.18e-09 · Best GWAS P=1.61e-08 conditioned to 0.0428

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous STAG3L2 0.16 0.03 enet 11 0.09 1.0e-07 -3.8 5.4 6.8e-08 -0.70 0.09 0.89 FALSE
2 GTEx Adipose Subcutaneous AC004166.6 0.09 0.08 lasso 2 0.07 3.9e-06 -5.4 -5.3 1.1e-07 0.84 0.02 0.97 FALSE
3 GTEx Adrenal Gland STAG3L2 0.14 0.07 enet 3 0.11 1.2e-04 -4.9 5.2 2.3e-07 -0.90 0.03 0.71 FALSE
4 GTEx Cells EBV-transformed lymphocytes PMS2P5 0.16 0.06 lasso 3 0.04 1.7e-02 -5.4 5.3 8.7e-08 -0.81 0.01 0.76 FALSE
5 GTEx Esophagus Gastroesophageal Junction PMS2P5 0.23 0.19 lasso 2 0.18 5.4e-07 -5.4 5.7 1.0e-08 -0.75 0.02 0.96 FALSE
6 GTEx Esophagus Mucosa PMS2P5 0.14 0.03 lasso 4 0.04 1.7e-03 -5.4 5.8 8.9e-09 -0.78 0.02 0.78 FALSE
7 GTEx Esophagus Muscularis STAG3L2 0.23 0.09 enet 33 0.15 1.9e-09 -3.8 5.5 3.3e-08 -0.77 0.03 0.97 FALSE
8 GTEx Heart Atrial Appendage PMS2P5 0.12 0.03 lasso 5 0.07 3.8e-04 -5.4 5.5 4.5e-08 -0.73 0.02 0.42 FALSE
9 GTEx Nerve Tibial PMS2P5 0.16 0.04 enet 34 0.08 3.5e-06 -3.8 5.1 2.9e-07 -0.67 0.02 0.96 FALSE
10 GTEx Nerve Tibial STAG3L2 0.36 0.09 enet 13 0.24 9.5e-17 -3.8 5.8 8.2e-09 -0.75 0.04 0.96 TRUE
11 GTEx Skin Sun Exposed Lower leg STAG3L2 0.15 0.05 enet 8 0.08 2.8e-07 -3.8 5.6 2.6e-08 -0.72 0.12 0.72 FALSE
12 GTEx Testis PMS2P5 0.22 0.13 lasso 2 0.13 3.1e-06 -5.4 5.2 1.7e-07 -0.73 0.02 0.90 FALSE
13 GTEx Thyroid GTF2IRD2B 0.03 0.04 lasso 1 0.03 1.9e-03 -5.6 -5.7 1.6e-08 1.00 0.01 0.86 FALSE
14 METSIM Adipose NCF1 0.05 0.03 blup 130 0.04 3.9e-07 -5.5 -5.3 1.1e-07 0.70 0.01 0.99 FALSE