[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor :

chr8:82,017,372-83,452,091

Best TWAS P=3.81e-08 · Best GWAS P=4.83e-09 conditioned to 0.0158

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland SNX16 0.40 0.17 lasso 12 0.16 1.7e-06 -4.9 -5.4 6.2e-08 0.77 0.06 0.94 FALSE
2 GTEx Cells Transformed fibroblasts SNX16 0.29 0.38 enet 26 0.40 1.2e-31 -5.7 -5.2 1.7e-07 0.82 0.03 0.97 FALSE
3 GTEx Colon Transverse SNX16 0.28 0.36 lasso 5 0.38 5.5e-19 -4.9 -5.2 2.3e-07 0.77 0.07 0.93 FALSE
4 GTEx Lung SNX16 0.40 0.41 lasso 7 0.46 1.8e-38 -4.9 -5.4 7.9e-08 0.85 0.04 0.96 FALSE
5 GTEx Nerve Tibial SNX16 0.29 0.29 lasso 4 0.32 2.6e-23 -5.7 -5.1 2.7e-07 0.85 0.03 0.97 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic SNX16 0.36 0.31 lasso 11 0.32 8.2e-18 -5.7 -5.5 3.8e-08 0.80 0.02 0.98 TRUE
7 GTEx Skin Sun Exposed Lower leg SNX16 0.27 0.32 lasso 7 0.31 8.4e-26 -5.2 -5.1 2.6e-07 0.85 0.09 0.91 FALSE
8 GTEx Stomach SNX16 0.26 0.16 lasso 10 0.18 4.5e-09 -4.9 -5.3 9.8e-08 0.92 0.03 0.97 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma SNX16 0.13 0.14 lasso 11 0.14 1.2e-08 -5.5 -5.2 2.5e-07 0.87 0.03 0.97 FALSE