Best TWAS P=3.81e-08 · Best GWAS P=4.83e-09 conditioned to 0.0158
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | SNX16 | 0.40 | 0.17 | lasso | 12 | 0.16 | 1.7e-06 | -4.9 | -5.4 | 6.2e-08 | 0.77 | 0.06 | 0.94 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | SNX16 | 0.29 | 0.38 | enet | 26 | 0.40 | 1.2e-31 | -5.7 | -5.2 | 1.7e-07 | 0.82 | 0.03 | 0.97 | FALSE |
3 | GTEx | Colon Transverse | SNX16 | 0.28 | 0.36 | lasso | 5 | 0.38 | 5.5e-19 | -4.9 | -5.2 | 2.3e-07 | 0.77 | 0.07 | 0.93 | FALSE |
4 | GTEx | Lung | SNX16 | 0.40 | 0.41 | lasso | 7 | 0.46 | 1.8e-38 | -4.9 | -5.4 | 7.9e-08 | 0.85 | 0.04 | 0.96 | FALSE |
5 | GTEx | Nerve Tibial | SNX16 | 0.29 | 0.29 | lasso | 4 | 0.32 | 2.6e-23 | -5.7 | -5.1 | 2.7e-07 | 0.85 | 0.03 | 0.97 | FALSE |
6 | GTEx | Skin Not Sun Exposed Suprapubic | SNX16 | 0.36 | 0.31 | lasso | 11 | 0.32 | 8.2e-18 | -5.7 | -5.5 | 3.8e-08 | 0.80 | 0.02 | 0.98 | TRUE |
7 | GTEx | Skin Sun Exposed Lower leg | SNX16 | 0.27 | 0.32 | lasso | 7 | 0.31 | 8.4e-26 | -5.2 | -5.1 | 2.6e-07 | 0.85 | 0.09 | 0.91 | FALSE |
8 | GTEx | Stomach | SNX16 | 0.26 | 0.16 | lasso | 10 | 0.18 | 4.5e-09 | -4.9 | -5.3 | 9.8e-08 | 0.92 | 0.03 | 0.97 | FALSE |
9 | The Cancer Genome Atlas | Colon Adenocarcinoma | SNX16 | 0.13 | 0.14 | lasso | 11 | 0.14 | 1.2e-08 | -5.5 | -5.2 | 2.5e-07 | 0.87 | 0.03 | 0.97 | FALSE |