[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr11:42,881,882-44,596,817

Best TWAS P=1.64e-08 · Best GWAS P=9.24e-10 conditioned to 0.00292

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Brain Cerebellar Hemisphere	HSD17B12	0.50	0.41	enet	33	0.29	3.0e-08	-4.9	5.6	1.6e-08	0.72	0.61	0.39	TRUE
6	GTEx	Whole Blood	RP11-613D13.5	0.06	0.01	lasso	4	0.00	1.2e-01	5.6	5.6	2.5e-08	0.83	0.04	0.58	FALSE
3	GTEx	Breast Mammary Tissue	RP11-613D13.5	0.18	0.11	lasso	5	0.15	6.3e-08	-4.3	5.4	6.2e-08	0.79	0.08	0.91	FALSE
4	GTEx	Esophagus Muscularis	RP11-613D13.5	0.21	0.20	lasso	2	0.19	9.6e-12	-4.3	5.3	1.2e-07	0.74	0.79	0.21	FALSE
1	GTEx	Adipose Visceral Omentum	HSD17B12	0.28	0.25	enet	17	0.21	2.6e-11	-4.3	5.3	1.3e-07	0.66	0.79	0.21	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	RP11-613D13.5	0.17	0.12	enet	19	0.15	2.2e-08	-4.9	5.3	1.3e-07	0.77	0.48	0.51	FALSE
7	The Cancer Genome Atlas	Rectum Adenocarcinoma	HSD17B12	0.39	0.25	lasso	4	0.26	7.2e-07	-4.8	5.2	1.8e-07	0.70	0.56	0.35	FALSE