Best TWAS P=6.2e-08 · Best GWAS P=2.01e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | CTB-31O20.6 | 0.16 | 0.07 | lasso | 5 | 0.05 | 7.8e-04 | 5.5 | 5.4 | 6.2e-08 | 0.99 | 0.01 | 0.99 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | KLF16 | 0.12 | 0.08 | bslmm | 372 | 0.08 | 1.0e-10 | 5.1 | 5.3 | 8.9e-08 | 0.43 | 0.03 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ATP8B3 | 0.04 | 0.01 | blup | 49 | 0.02 | 2.2e-03 | 5.1 | 5.4 | 8.1e-08 | 0.55 | 0.01 | 0.25 | FALSE |