Best TWAS P=1.93e-07 · Best GWAS P=1.25e-06 conditioned to 0.683
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | MARCH2 | 0.34 | 0.30 | enet | 22 | 0.32 | 6.9e-20 | -4.6 | -5.2 | 1.9e-07 | 0.90 | 0.01 | 0.97 | TRUE |
2 | GTEx | Lung | MARCH2 | 0.36 | 0.25 | lasso | 8 | 0.29 | 2.8e-22 | -4.5 | -5.2 | 2.5e-07 | 0.88 | 0.01 | 0.96 | FALSE |