TWAS
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Traits
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Angina
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chr9:21,303,958-22,819,407
Best TWAS P=2.16e-22 · Best GWAS P=1.22e-34 conditioned to 1.57e-14
21.4M
21.6M
21.8M
22M
22.2M
22.4M
22.6M
22.8M
0
10
20
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
CDKN2B
0.08
0.05
lasso
4
0.06
2.4e-07
9.5
9.7
2.2e-22
0.59
0.97
0.02
TRUE
2
CommonMind
Brain Pre-frontal Cortex
CDKN2B-AS1
0.11
0.02
blup
501
0.03
1.7e-04
9.5
8.7
2.5e-18
0.62
0.10
0.88
TRUE