TWAS
hub
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Usage
Models
Genes
Traits
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Traits
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Angina
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chr6:160,071,844-161,571,560
Best TWAS P=8.96e-08 · Best GWAS P=5.19e-16 conditioned to 1.74e-08
160M
160.2M
160.4M
160.6M
160.8M
161M
161.2M
161.4M
161.6M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
SLC22A3
0.10
0.02
blup
582
0.05
4.4e-07
2.5
5.3
9.0e-08
0.09
0.93
0.05
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
SLC22A1
0.04
0.01
enet
17
0.01
5.2e-04
4.1
-5.3
1.5e-07
-0.59
0.01
0.94
TRUE