49 significantly associated models · 16 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 109098737 | 110517617 | 3 | 1 | 3.3e-12 | 3.3e-12 | 2.2e-01 | 97 | SORT1 |
2 | 1 | 222133118 | 223529093 | 1 | 1 | 7.2e-08 | 7.8e-07 | 5.9e-01 | 99 | RP11-378J18.8 |
3 | 6 | 12020241 | 13990267 | 2 | 1 | 2.3e-08 | 2.5e-08 | 1.0e+00 | 100 | RP1-257A7.5 |
4 | 6 | 133961374 | 134468561 | 1 | 1 | 1.6e-09 | 9.0e-08 | 7.3e-01 | 100 | TCF21 |
5 | 6 | 160071844 | 161571560 | 2 | 2 | 9.0e-08 | 5.2e-16 | 1.7e-08 | 52 | SLC22A1 SLC22A3 |
6 | 9 | 21303958 | 22819407 | 2 | 2 | 2.2e-22 | 1.2e-34 | 1.6e-14 | 61 | CDKN2B CDKN2B-AS1 |
7 | 15 | 78360691 | 79802863 | 2 | 2 | 9.8e-11 | 5.7e-10 | 2.7e-01 | 97 | ADAMTS7 |
8 | 15 | 90718541 | 92135418 | 2 | 1 | 1.3e-11 | 1.4e-08 | 4.3e-01 | 98 | FES |
9 | 17 | 47119135 | 47685050 | 1 | 1 | 8.0e-08 | 2.3e-09 | 8.5e-03 | 81 | ZNF652 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Artery Aorta | 2 | 0.067 | 1.4 |
GTEx | Artery Tibial | 3 | 0.080 | 1.4 |
GTEx | Brain Cortex | 0 | 0.000 | 1.4 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.4 |
GTEx | Cells EBV-transformed lymphocytes | 1 | 0.070 | 1.4 |
GTEx | Liver | 1 | 0.139 | 1.4 |
GTEx | Skin Sun Exposed Lower leg | 1 | 0.027 | 1.4 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.4 |
GTEx | Vagina | 0 | 0.000 | 1.4 |
CommonMind | Brain Pre-frontal Cortex | 5 | 0.093 | 1.4 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 2 | 0.121 | 1.4 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 1 | 0.091 | 1.4 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 2 | 0.097 | 1.4 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 1 | 0.037 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 2 | 0.098 | 1.4 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 2 | 0.181 | 1.4 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 2 | 0.068 | 1.4 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 1 | 0.040 | 1.4 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 1 | 0.059 | 1.4 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 1 | 0.078 | 1.4 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.4 |
GTEx | Adipose Subcutaneous | 0 | 0.000 | 1.3 |
GTEx | Adipose Visceral Omentum | 1 | 0.049 | 1.3 |
GTEx | Adrenal Gland | 0 | 0.000 | 1.3 |
GTEx | Artery Coronary | 0 | 0.000 | 1.3 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.3 |
GTEx | Brain Cerebellar Hemisphere | 1 | 0.067 | 1.3 |
GTEx | Brain Cerebellum | 0 | 0.000 | 1.3 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.3 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.3 |
GTEx | Breast Mammary Tissue | 0 | 0.000 | 1.3 |
GTEx | Cells Transformed fibroblasts | 1 | 0.024 | 1.3 |
GTEx | Colon Transverse | 0 | 0.000 | 1.3 |
GTEx | Esophagus Gastroesophageal Junction | 0 | 0.000 | 1.3 |
GTEx | Esophagus Mucosa | 1 | 0.030 | 1.3 |
GTEx | Esophagus Muscularis | 0 | 0.000 | 1.3 |
GTEx | Heart Atrial Appendage | 0 | 0.000 | 1.3 |
GTEx | Heart Left Ventricle | 0 | 0.000 | 1.3 |
GTEx | Lung | 1 | 0.035 | 1.3 |
GTEx | Muscle Skeletal | 1 | 0.035 | 1.3 |
GTEx | Nerve Tibial | 0 | 0.000 | 1.3 |
GTEx | Ovary | 0 | 0.000 | 1.3 |
GTEx | Pancreas | 0 | 0.000 | 1.3 |
GTEx | Pituitary | 0 | 0.000 | 1.3 |
GTEx | Prostate | 0 | 0.000 | 1.3 |
GTEx | Skin Not Sun Exposed Suprapubic | 0 | 0.000 | 1.3 |
GTEx | Spleen | 0 | 0.000 | 1.3 |
GTEx | Stomach | 0 | 0.000 | 1.3 |
GTEx | Testis | 0 | 0.000 | 1.3 |
GTEx | Thyroid | 1 | 0.025 | 1.3 |
GTEx | Uterus | 0 | 0.000 | 1.3 |
GTEx | Whole Blood | 1 | 0.050 | 1.3 |
METSIM | Adipose | 1 | 0.022 | 1.3 |
NTR | Blood | 0 | 0.000 | 1.3 |
ROSMAP | Brain Pre-frontal Cortex | 2 | 0.046 | 1.3 |
YFS | Blood | 1 | 0.022 | 1.3 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 3 | 0.068 | 1.3 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 1 | 0.098 | 1.3 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 1 | 0.024 | 1.3 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 1 | 0.023 | 1.3 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 1 | 0.063 | 1.3 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 1 | 0.022 | 1.3 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Thyroid Carcinoma | 1 | 0.019 | 1.3 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.2 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.2 |
GTEx | Breast Mammary Tissue (Male) | 0 | 0.000 | 1.2 |
GTEx | Breast Mammary Tissue (Female) | 0 | 0.000 | 1.2 |
GTEx | Colon Sigmoid | 0 | 0.000 | 1.2 |