TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
High blood pressure
:
→
chr1:7,715,776-9,571,422
Best TWAS P=2.25e-08 · Best GWAS P=6.7e-08 conditioned to 0.29
8M
8.5M
9M
9.5M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Mucosa
RP5-1115A15.1
0.06
0.06
lasso
4
0.05
3.0e-04
-5.4
5.6
2.2e-08
-0.87
0.03
0.92
TRUE
3
GTEx
Skin Not Sun Exposed Suprapubic
RP5-1115A15.1
0.08
0.04
enet
8
0.04
3.0e-03
-5.3
5.5
4.8e-08
-0.97
0.02
0.95
FALSE
4
GTEx
Whole Blood
RERE
0.19
0.15
lasso
4
0.13
2.7e-12
-5.4
5.4
8.1e-08
-0.86
0.01
0.99
FALSE
1
GTEx
Esophagus Mucosa
RERE
0.13
0.16
lasso
3
0.16
7.2e-11
-5.4
5.3
9.1e-08
-0.86
0.01
0.98
FALSE