Best TWAS P=8.14e-09 · Best GWAS P=8.84e-08 conditioned to 7e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | TSPY26P | 0.08 | 0.01 | lasso | 4 | 0.03 | 1.7e-03 | -4.4 | -5.8 | 8.1e-09 | -0.10 | 0.10 | 0.55 | TRUE |
2 | GTEx | Artery Aorta | KIF3B | 0.15 | 0.00 | enet | 33 | 0.00 | 2.9e-01 | -2.8 | 5.2 | 2.0e-07 | 0.07 | 0.04 | 0.23 | FALSE |
3 | GTEx | Brain Cerebellum | TSPY26P | 0.25 | 0.06 | lasso | 6 | 0.15 | 2.9e-05 | 3.8 | -5.2 | 2.3e-07 | -0.09 | 0.07 | 0.23 | FALSE |
4 | NTR | Blood | C20orf160 | 0.01 | 0.00 | bslmm | 305 | 0.00 | 8.0e-03 | -4.4 | 5.5 | 3.2e-08 | 0.10 | 0.03 | 0.08 | TRUE |