TWAS
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Models
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Traits
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Traits
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High blood pressure
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chr20:29,927,166-31,615,615
Best TWAS P=8.14e-09 · Best GWAS P=8.84e-08 conditioned to 7e-06
30M
30.2M
30.4M
30.6M
30.8M
31M
31.2M
31.4M
31.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
TSPY26P
0.08
0.01
lasso
4
0.03
1.7e-03
-4.4
-5.8
8.1e-09
-0.10
0.10
0.55
TRUE
4
NTR
Blood
C20orf160
0.01
0.00
bslmm
305
0.00
8.0e-03
-4.4
5.5
3.2e-08
0.10
0.03
0.08
TRUE
2
GTEx
Artery Aorta
KIF3B
0.15
0.00
enet
33
0.00
2.9e-01
-2.8
5.2
2.0e-07
0.07
0.04
0.23
FALSE
3
GTEx
Brain Cerebellum
TSPY26P
0.25
0.06
lasso
6
0.15
2.9e-05
3.8
-5.2
2.3e-07
-0.09
0.07
0.23
FALSE