TWAS hub - C20orf160

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0107	0.0063	7.9e-03	-0.001	0.005	-0.001	0.005	-0.001	9.4e-01	9.1e-03	7.5e-01	0.008	9.9e-01
2	TCGA	Breast Invasive Carcinoma	0.0125	0.0071	4.1e-03	0.009	0.010	0.007	NA	0.008	3.9e-03	3.4e-03	1.1e-02	NA	6.4e-03
3	TCGA	Brain Lower Grade Glioma	0.0378	0.0216	1.6e-03	0.026	0.021	0.026	NA	0.040	5.2e-04	1.7e-03	4.9e-04	NA	2.3e-05
4	TCGA	Lung Adenocarcinoma	0.0477	0.0277	8.5e-04	0.025	0.023	0.013	NA	0.017	5.8e-04	8.7e-04	1.0e-02	NA	3.6e-03
5	TCGA	Thyroid Carcinoma	0.0780	0.0320	3.9e-06	0.074	0.069	0.063	NA	0.064	1.0e-07	2.7e-07	9.1e-07	NA	7.7e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
Chronic bronchitis/emphysema (father)	5.7	6.7	8.8	1.5	3.0	2.6	2.8	2.8
Maternal smoking around birth	5.4	7.8	18.8	4.3	1.9	2.5	2.1	2.4
Medication: Blood pressure	5.0	8.9	19.9	4.5	-3.0	-1.1	-2.9	-2.4
Mouth/teeth dental problems: Mouth ulcers	4.6	7.4	10.5	0.3	-3.0	-3.2	-2.8	-3.1
Townsend deprivation index at recruitment	3.9	5.4	7.9	2.8	2.0	2.0	2.2	2.6
Mouth/teeth dental problems	3.6	5.6	10.6	-0.6	3.3	2.3	2.9	1.7
Osteoarthritis (self-reported)	3.6	4.6	7.1	0.9	-2.6	-2.7	-1.8	-2.3
Ever highly irritable/argumentative for 2 days	3.3	4.0	7.0	-0.2	1.9	2.6	2.2	2.2
Ever taken oral contraceptive pill	3.3	3.7	6.9	1.9	-2.6	-1.0	-2.0	-1.8
Financial situation satisfaction	3.3	4.1	7.0	1.8	2.0	2.0	1.5	2.6
Blood Red Count	3.2	30.6	139.2	11.8	1.3	1.4	1.8	2.7
Average weekly champagne plus white wine intake	3.0	4.1	7.4	-0.9	-2.4	-2.0	-2.7	-1.6
Schizophrenia (2018)	2.9	6.1	10.1	1.5	-3.0	0.0	-3.0	-3.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.8	3.4	4.5	-0.5	2.1	2.0	2.1	1.9
Irritable Bowel Disease (IBD)	2.7	6.5	10.8	1.4	-3.2	-2.7	-3.3	-1.5
Medication for cholesterol, blood pressure or diabetes	2.7	4.5	13.7	-3.7	2.0	0.2	2.1	0.9
Medication for pain relief, constipation, heartburn	2.7	4.6	19.7	-4.4	0.1	1.4	-0.9	0.7
Supplements: Vitamin C	2.7	3.1	5.5	0.5	2.4	1.6	2.0	1.8
Diastolic blood pressure, automated reading	2.7	8.4	41.3	6.4	-0.1	0.1	0.8	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	3.9	5.8	2.0	1.2	2.4	1.6	2.4
Medication: Paracetamol	2.6	4.0	12.9	3.6	-1.0	-2.2	0.1	-1.1
Vascular/heart problems diagnosed by doctor	2.6	7.0	33.5	-5.8	0.5	-0.8	-0.6	0.4
Ulcerative Colitis	2.5	3.6	8.2	0.1	-2.1	-1.9	-2.9	-1.4
Medication: Paracetamol	2.5	4.2	15.9	4.0	-0.9	-1.8	-0.2	-1.1
Exposure to tobacco smoke outside home	2.5	3.4	7.2	2.7	1.8	0.8	2.1	1.2
Average weekly red wine intake	2.5	3.7	5.6	1.0	2.1	2.4	1.3	2.4
Alzheimer’s Disease (in father)	2.4	2.6	4.7	0.1	-2.0	-1.4	-2.2	-1.5
Mean Putamen Volume	2.4	2.8	9.1	3.0	-1.2	-0.9	-1.5	-0.5
Neuroticism (2016)	2.4	3.5	6.3	0.1	-2.3	0.0	-2.5	-2.5
Average weekly spirits intake	2.3	2.9	10.7	3.3	0.1	1.7	0.3	0.8
High blood pressure	2.3	6.5	30.6	5.5	-1.0	0.4	0.1	-0.8
Hypertension (Self-reported)	2.3	6.5	30.0	5.5	-1.0	0.2	0.1	-1.1
Long-standing illness, disability or infirmity	2.3	3.6	7.5	2.7	-1.9	-1.3	-1.7	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.4	4.3	2.1	1.9	1.2	1.1	1.2
Crohns Disease (2017)	2.2	4.8	9.7	1.2	-3.1	-2.4	-2.4	-1.3
Ever had hysterectomy (womb removed)	2.1	2.3	7.2	2.7	-1.8	-0.9	-0.2	-0.5
Falls in the last year	2.1	2.8	9.1	3.0	-1.0	-1.5	-0.6	-1.1
High cholesterol (Self-reported)	2.1	3.7	10.6	3.2	0.7	1.8	1.1	1.7
Cardiovascular Disease	2.0	6.5	29.4	5.4	-0.4	1.2	1.1	0.5
Medication: Simvastatin	2.0	3.0	11.6	3.4	0.1	1.4	0.3	1.1
Glaucoma (self-reported)	2.0	2.3	4.6	0.2	-1.4	-2.1	-0.8	-2.1
Medication: Allopurinol	2.0	2.7	7.0	2.6	1.5	1.6	1.1	0.6
Family relationship satisfaction	2.0	2.4	5.8	0.0	1.4	2.4	1.5	1.4
Illness, injury, bereavement, stress in last 2 years	2.0	2.5	7.7	-2.8	0.4	1.2	1.7	0.4
Handedness (chirality/laterality): Left-handed	2.0	2.5	4.3	-1.2	1.1	2.1	1.6	1.7
Medication: Gliclazide	2.0	2.3	8.8	3.0	0.8	0.5	0.3	1.3
Exposure to tobacco smoke at home	1.9	2.1	4.7	2.2	1.2	1.2	1.3	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	8.3	2.9	1.3	0.2	1.5	0.6
Mother’s age at death	1.9	2.4	11.0	-3.3	0.2	-0.3	-0.6	0.5
Length of working week for main job	1.8	1.9	9.6	3.1	0.1	-0.1	-0.1	0.3
Age at first live birth	1.8	3.1	6.3	-2.5	-1.5	-1.3	-1.9	-1.3
Eye problems/disorders: None of the above	1.8	2.0	5.7	2.4	1.3	1.2	1.0	0.8
Eye problems/disorders: Cataract	1.8	2.0	6.3	-2.5	1.3	1.0	0.8	0.8
Schizophrenia (2014)	1.7	3.8	6.8	0.2	-2.6	0.0	-2.3	-2.6
Other serious medical condition/disability diagnosed by doctor	1.7	2.3	3.6	1.3	-1.6	-1.3	-1.9	-1.4
Alcohol intake versus 10 years previously	1.7	2.6	3.9	1.4	1.6	1.4	2.0	1.6
Hair/balding pattern: Pattern 3	1.7	2.5	3.9	-2.0	-1.4	-1.4	-1.4	-1.6
Number of live births	1.7	2.4	3.6	-0.4	1.9	1.2	1.8	1.8
Ovarian Cancer	1.6	2.1	4.7	-0.1	-2.2	-0.9	-1.9	-1.2
Pulse wave Arterial Stiffness index	1.6	1.9	3.2	-1.8	-0.9	-1.8	-0.3	-1.5
Suffer from ‘nerves’	1.6	2.5	4.5	-0.4	2.1	1.8	1.6	1.4
Overall health rating	1.6	3.5	16.5	4.1	-0.1	0.9	0.0	0.2
Commuting to job workplace: Public transport	1.6	1.9	8.8	3.0	0.4	0.1	-0.4	0.6
Illnesses of father: High blood pressure	1.6	2.0	6.7	2.6	0.8	1.2	0.2	1.2
Lupus	1.5	2.3	4.3	-0.3	1.9	1.0	1.5	2.1
Gout (self-reported)	1.5	2.0	9.2	3.0	0.0	0.9	0.0	-0.0
Age at last live birth	1.5	2.1	4.1	-2.0	-1.3	-1.1	-1.5	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.1	8.3	2.9	-0.3	-1.9	-0.0	-1.8
Number of self-reported non-cancer illnesses	1.5	2.6	7.8	2.8	-1.6	-0.8	-0.9	-1.1
Ulcerative Colitis (UC)	1.4	2.6	5.6	1.3	-1.4	-1.8	-2.4	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	11.7	-3.4	0.2	1.6	0.2	1.3
Medication: Levothyroxine sodium	1.4	2.3	3.5	-1.2	-1.8	-1.9	-1.2	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.3	15.0	-3.9	-0.4	0.8	-0.4	0.6
Medication: Cholesterol lowering	1.4	2.2	8.7	2.9	-0.5	1.2	-0.5	0.7
Medication for cholesterol	1.4	2.1	6.1	-2.5	-0.3	-0.7	-2.0	-0.3
Myopia	1.4	2.1	5.2	1.4	-1.3	-0.4	-2.3	-1.2
HbA1C	1.3	1.5	2.4	0.1	-1.4	-1.5	-1.2	-1.3
Blood Platelet Count	1.3	15.2	36.5	6.0	3.5	2.5	4.2	2.0
Number of treatments/medications taken	1.3	2.3	8.8	3.0	-0.7	-1.1	-0.0	-0.9
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	5.2	0.1	0.2	2.3	0.5	1.6
Father’s age at death	1.3	1.8	5.7	-2.4	1.3	-0.8	1.0	0.1
Number of full brothers	1.3	1.6	4.0	0.0	0.2	1.8	0.9	2.0
Pulse wave peak to peak time	1.3	1.5	3.1	1.4	0.6	1.7	0.1	1.4
Qualifications: College or University degree	1.3	4.2	5.4	-1.5	-2.3	-2.0	-2.0	-2.3
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	6.6	2.6	-0.6	1.0	-0.1	-0.0
Illnesses of siblings: Diabetes	1.3	1.6	5.7	2.4	-0.2	1.1	0.9	-0.1
Medication: Lisinopril	1.3	1.7	2.7	1.6	-1.4	-0.5	-0.9	-1.6
Triglycerides	1.2	2.0	3.7	1.9	-1.4	0.0	-1.9	-0.8
Heel T-Score	1.2	9.3	45.4	-6.7	-0.6	-0.0	-0.3	-0.7
BMI	1.2	6.9	22.4	4.7	0.4	1.5	2.1	2.3
Type 2 Diabetes (T2D) (2018)	1.2	2.3	4.8	2.2	-1.8	-1.2	-1.2	-0.7
Average weekly fortified wine intake	1.2	1.4	3.4	-1.8	-0.3	-1.0	-1.0	-1.2
Taking other prescription medications	1.2	1.8	6.5	2.5	-1.0	-0.4	-0.7	-0.9
Serious illness, injury or assault to yourself	1.2	1.5	7.4	2.7	-0.1	-0.2	0.3	0.1
Sitting height	1.2	8.3	26.4	-5.1	-3.3	-0.8	-1.8	-0.6
Number of incorrect matches in round	1.2	2.0	2.9	1.7	-1.1	-1.3	-1.5	-1.3
Headache pain in last month	1.2	2.1	9.6	3.1	-0.7	-0.1	0.2	-0.5
Medication: Atorvastatin	1.2	1.5	4.4	1.4	0.5	1.0	0.2	2.1
Fractured/broken bones in last 5 years	1.2	1.5	7.3	2.7	0.1	0.2	0.2	-0.2
Cholesterol lowering medication	1.2	1.8	5.4	2.3	0.1	1.0	1.0	1.2
Alcohol drinker status: Previous	1.2	1.4	3.6	0.9	1.0	1.1	0.5	1.9
Systolic Blood Pressure	1.1	5.5	26.2	5.1	0.3	0.8	0.6	-0.1
Diabetes (mother)	1.1	1.4	3.4	1.4	0.9	1.9	-0.0	0.9
Financial difficulties in last 2 years	1.1	1.5	7.0	2.6	-0.5	-0.2	-0.5	-0.3
Worrier / anxious feelings	1.1	2.0	4.1	-1.7	-0.2	-1.6	-0.5	-2.0
Loud music exposure frequency	1.1	1.2	5.6	2.4	-0.2	0.6	0.2	0.4
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	3.7	-1.5	-1.5	-1.9	-1.2	-1.0
Comparative body size at age 10	1.1	3.1	4.8	0.2	1.9	1.8	2.2	1.9
Hearing aid user	1.1	1.2	2.0	-0.7	-0.5	-1.4	-1.1	-1.4
Medication: Blood pressure	1.1	2.1	5.8	2.4	0.9	0.4	1.9	0.4
Ever depressed for a whole week	1.1	1.4	2.5	1.6	-0.7	1.4	-0.1	1.4
Bipolar Disorder or Schizophrenia	1.0	2.6	4.5	0.8	-1.9	-0.6	-1.9	-2.1
Schizophrenia vs Biploar Disorder	1.0	1.4	3.0	-0.0	-1.7	0.0	-1.4	-1.3
Prostate Cancer	1.0	1.5	2.1	-0.3	1.4	1.3	1.5	1.2
Systolic blood pressure, automated reading	1.0	3.0	13.7	3.7	0.6	0.3	0.8	-0.2
Medication: Co-codamol	1.0	1.1	2.2	0.9	-1.1	0.2	-1.1	-1.5
Illnesses of siblings	1.0	1.4	4.2	-2.1	1.2	0.1	0.3	1.1
Pulse rate, automated reading	1.0	3.2	14.7	3.8	0.2	0.7	0.2	0.7
Diabetes diagnosed by doctor	1.0	1.6	3.2	1.6	-1.8	-0.6	-1.3	-0.3
Pain experienced in last month	1.0	1.7	7.4	-2.7	0.5	0.7	0.2	0.6
Verbal and Numeric Reasoning (VNR)	0.9	2.1	9.5	-3.1	0.2	0.6	0.3	0.6
Age at First Birth	0.9	1.3	5.0	-2.2	0.6	0.0	-0.1	-1.1
Tanning	0.9	10.9	28.5	1.4	-5.3	-2.1	-3.8	-2.3
Medication for hormone replacement therapy	0.9	1.0	2.4	1.2	-1.5	-0.3	-0.8	-0.6
Multivitamins +/- minerals	0.9	1.1	3.3	-1.4	-0.6	0.1	-1.8	-0.4
Stomach or abdominal pain in last month	0.9	1.1	2.4	1.5	0.5	0.4	1.6	0.5
Medication: Atenolol	0.9	1.2	4.7	2.2	0.6	0.1	0.8	-0.4
Body mass index (BMI)	0.9	3.9	10.1	3.2	0.9	1.0	2.3	1.6
Pain all over the body in last month	0.9	1.0	3.3	1.8	0.4	0.8	0.4	0.8
Mouth/teeth dental problems: Dentures	0.9	1.6	4.4	0.2	-2.1	-0.1	-1.8	-0.4
Illnesses of mother	0.9	1.1	5.1	-2.3	-0.1	0.0	0.4	-0.2
Hair/balding pattern: Pattern 4	0.9	2.1	5.7	2.4	0.5	1.5	0.6	1.3
Shortness of breath walking on level ground	0.9	1.0	2.9	0.2	1.0	0.0	1.7	1.1
Emphysema/chronic bronchitis	0.9	1.1	2.7	-1.6	-0.1	0.7	0.3	1.4
Eye problems/disorders: Glaucoma	0.9	1.1	2.4	0.4	-0.6	-1.5	-0.4	-1.5
Heart disease (siblings)	0.9	1.1	4.9	2.2	0.2	0.2	-0.6	0.1
Major Depression (MDD)	0.8	0.9	2.1	1.5	-0.8	0.0	-0.6	-1.2
Breast Cancer	0.8	1.8	8.4	-2.9	-0.5	0.5	-0.3	-0.3
Supplements: Zinc	0.8	0.9	3.1	1.8	0.2	1.0	0.2	0.4
Qualifications: None of the above	0.8	1.7	3.7	0.4	1.9	1.0	1.6	1.1
Arm fat percentage (right)	0.8	3.3	7.8	2.8	1.0	1.3	1.5	1.9
Medication: Amlodipine	0.8	1.1	2.7	0.6	-1.6	0.3	-1.4	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.0	0.5	-1.4	-1.2	-0.7	-0.5
Back pain experienced in last month	0.8	1.2	3.5	-1.9	0.4	0.0	1.3	0.8
Risk taking	0.8	1.2	2.6	1.6	0.5	1.2	0.8	1.1
Alzheimer’s Disease (including proxy)	0.7	1.0	1.7	-0.3	-1.2	-1.2	-1.3	-0.5
Bipolar Disorder (2011)	0.7	0.7	3.4	-1.9	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.7	1.2	2.6	1.3	-1.6	0.0	-1.2	-0.6
Lung FVC	0.7	3.5	11.1	3.3	1.6	-0.3	1.8	-0.6
Sensitivity / hurt feelings	0.7	1.1	2.7	-1.3	-0.3	-1.0	-0.6	-1.6
Angina	0.7	0.9	3.4	1.8	-0.4	0.7	0.1	0.5
Qualifications: CSEs or equivalent	0.7	1.0	2.9	1.7	-1.2	0.6	0.1	0.1
Had other major operations	0.7	0.9	3.9	2.0	-0.4	-0.2	0.0	-0.6
Peak expiratory flow (PEF)	0.7	1.7	3.1	0.7	1.8	1.0	1.7	1.1
Medication: Ventolin 100micrograms inhaler	0.7	0.9	4.1	-2.0	-0.1	-0.1	0.5	-0.0
High blood pressure (siblings)	0.7	1.0	2.2	0.7	-1.5	-0.6	-0.7	-1.2
Leg pain on walking	0.7	0.8	2.8	1.7	-0.6	-0.6	0.1	-0.8
Medication: Aspirin	0.7	0.9	4.0	2.0	-0.6	-0.5	-0.2	-0.2
Arm fat percentage (left)	0.7	2.8	6.6	2.6	1.0	1.1	1.5	1.8
Medication: Aspirin	0.7	0.9	4.1	2.0	-0.7	-0.2	-0.1	-0.0
Wears glasses or contact lenses	0.7	0.8	3.1	-1.8	0.3	0.1	-0.0	0.8
Medication: Bendroflumethiazide	0.7	1.1	4.3	2.1	0.1	0.2	0.6	-0.8
Alcohol drinker status: Never	0.7	0.8	2.9	-1.7	0.9	-0.0	-0.1	0.7
Average weekly beer plus cider intake	0.7	1.0	2.4	-0.3	1.5	0.3	1.5	0.4
Age started oral contraceptive pill	0.7	0.9	2.3	-0.2	0.1	-1.5	-0.2	-1.5
Coronary Artery Disease (CAD)	0.6	0.7	2.1	1.4	0.9	0.0	0.1	0.7
Type 2 Diabetes (T2D) (2012)	0.6	0.6	2.3	0.2	-1.5	0.0	-0.9	-0.3
Chronotype (morning person)	0.6	1.4	3.7	-1.9	1.0	0.4	1.3	0.2
Medication: Metformin	0.6	0.9	3.0	1.7	-0.3	0.3	-0.5	1.0
Diabetes (father)	0.6	0.8	1.3	-0.1	-1.0	-0.7	-1.1	-1.0
Age when periods started (menarche)	0.6	1.5	3.8	-0.9	0.8	1.3	0.6	2.0
High blood pressure (mother)	0.6	0.9	2.1	1.0	-1.0	-0.5	-1.5	-0.1
Past tobacco smoking	0.6	1.1	2.4	0.0	-0.4	-1.5	-1.3	-1.0
Hearing difficulty/problems with background noise	0.6	1.0	1.8	-1.3	1.1	1.3	0.3	0.6
Diabetes (self-reported)	0.6	0.9	1.8	1.4	-1.3	-0.6	-0.8	-0.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	1.9	0.1	1.4	0.9	0.7	0.7
Qualifications: A levels/AS levels or equivalent	0.6	1.2	4.9	-2.2	-0.5	0.1	-0.9	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	3.1	1.8	-0.2	-0.6	0.7	-0.3
Prospective memory result	0.6	0.8	2.0	-0.8	-0.3	-1.4	-0.8	-0.7
Arm fat mass (right)	0.6	2.5	6.3	2.5	0.6	1.0	1.6	1.6
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.6	0.6	-0.6	-1.3	-1.2	-0.4
Chronic bronchitis/emphysema (mother)	0.6	0.7	3.2	1.8	0.1	0.2	0.3	0.4
Medication: Ibuprofen	0.6	0.7	1.4	1.2	-0.8	-1.2	0.2	-0.5
Medication: Seretide 50 evohaler	0.6	0.7	1.4	1.1	1.2	0.5	0.6	0.5
Knee pain experienced in last month	0.6	0.9	3.7	1.9	-0.6	-0.3	0.2	-0.8
Qualifications: nursing, teaching	0.6	0.9	3.1	0.2	-1.0	-0.5	-1.8	-0.2
Illnesses of father: None of the above (group 1)	0.6	0.7	2.7	-1.6	-0.5	-0.1	-0.6	-0.6
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.6	1.6	-0.9	-0.4	-0.3	-0.6
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.6	-1.1	0.8	0.7	0.3	1.3
Leg fat percentage (left)	0.6	2.2	8.1	2.9	0.1	0.9	0.8	1.2
Reaction Time	0.5	1.0	1.7	-1.3	0.8	1.3	0.2	0.8
Body Mass Index (BMI) (2010)	0.5	0.7	1.8	0.1	-1.3	0.0	-0.8	-1.1
HDL Cholesterol	0.5	0.8	3.4	-1.8	0.3	0.0	0.6	-0.5
Hypothyroidism (self reported)	0.5	1.1	2.0	-0.7	-1.2	-1.4	-1.0	-0.8
Hearing difficulty/problems: Yes	0.5	0.8	3.2	-1.8	0.0	0.8	-0.2	0.2
Relative age of first facial hair	0.5	0.9	4.6	-2.1	-0.1	-0.3	0.0	0.0
Pack years adult smoking proportion	0.5	0.7	1.7	1.1	0.4	0.3	0.7	1.3
Hand grip strength (right)	0.5	1.2	3.0	0.3	0.3	1.1	1.3	1.7
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.7	1.3	-0.8	-0.5	-0.0	-0.3
Nervous feelings	0.5	1.0	2.4	-1.6	1.2	0.7	0.8	0.4
Fluid intelligence score	0.5	1.0	1.8	-1.1	0.7	1.3	0.4	1.0
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	3.7	1.1	1.5	0.0	1.9	0.9
Standing height	0.5	4.8	10.4	-3.2	-2.6	-1.1	-2.2	-0.8
Pulse wave reflection index	0.5	0.7	1.7	0.1	-0.6	-1.3	-0.3	-1.1
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.5	-0.9	1.1	0.3	1.2	0.6
Birth weight	0.5	1.0	3.7	-1.9	-0.4	-0.2	0.5	1.1
Leg fat percentage (right)	0.5	2.0	4.0	2.0	0.5	1.1	1.2	1.7
Worry too long after embarrassment	0.5	0.9	2.3	-0.6	-0.5	-1.2	-0.4	-1.5
Number of children fathered	0.5	0.6	1.7	-0.3	-1.3	-0.0	-1.0	0.0
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.8	-1.3	-0.7	-0.6	-0.5	0.0
Neck or shoulder pain in last month	0.5	0.8	3.2	1.8	-0.6	-0.2	-0.4	0.0
Mean time to correctly identify matches	0.5	0.9	2.9	-1.7	0.4	1.0	-0.2	0.6
Alcohol intake frequency.	0.5	1.2	3.1	1.8	1.1	0.4	1.3	0.2
Friendships satisfaction	0.5	0.7	1.6	0.5	0.3	1.3	1.2	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.8	1.4	0.1	-0.0	0.7	0.9
Mineral and other dietary supplements	0.5	0.7	1.3	0.9	-0.6	-0.9	0.2	-1.2
Breast cancer (self-reported)	0.5	0.6	1.9	1.4	-0.2	0.7	0.1	0.8
Osteoporosis (self-reported)	0.5	0.6	1.3	-0.1	0.3	1.2	1.1	0.8
Arm fat mass (left)	0.5	2.1	5.6	2.4	0.3	0.8	1.4	1.6
Ever smoked	0.5	0.9	1.6	0.0	0.7	1.2	1.3	1.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	1.6	1.2	0.4	-0.3	1.3	0.3
Blood Eosinophil Count	0.4	2.9	10.5	3.2	-1.8	0.5	-0.8	0.3
Height	0.4	7.5	16.8	-4.1	-3.2	-1.6	-2.5	-1.1
Allergy or Eczema	0.4	0.9	2.2	-0.3	-1.5	-0.4	-1.5	0.2
Respiratory disease	0.4	0.9	3.4	-1.8	-0.1	0.9	-0.5	0.4
Lung FEV1/FVC ratio	0.4	2.1	4.7	-0.1	1.8	0.3	2.2	1.6
Hair Pigment	0.4	10.4	19.7	4.2	4.4	1.9	2.7	1.9
Hand grip strength (left)	0.4	1.1	2.3	0.2	-0.2	1.5	1.1	1.4
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.6	-0.0	0.5	0.2	1.3	0.9
Current tobacco smoking	0.4	0.6	1.6	0.7	-0.1	1.3	0.0	1.0
Supplements: Glucosamine	0.4	0.5	0.9	0.0	-0.7	-0.9	-1.0	-0.5
Waist circumference	0.4	1.3	4.8	2.2	-0.2	0.4	0.8	1.0
Hair/balding pattern: Pattern 2	0.4	0.4	0.8	-0.9	0.7	0.2	0.9	-0.2
Heart attack	0.4	0.6	1.5	1.2	-0.5	0.7	-0.0	0.8
Allergy	0.4	0.8	1.5	1.2	1.2	-0.3	0.8	-0.5
Medication: Ramipril	0.4	0.5	1.4	1.2	-0.8	-0.7	0.3	-0.2
Depression (self-reported)	0.4	0.5	0.8	0.8	-0.9	0.0	-0.8	-0.6
Birth weight of first child	0.4	0.7	1.0	1.0	0.7	1.0	0.8	0.9
Angina (self-reported)	0.4	0.6	1.8	1.4	-0.5	0.6	0.1	0.5
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.8	-1.3	-0.4	0.2	0.3	-0.6
Illnesses of father: Heart disease	0.4	0.5	1.8	1.3	0.5	0.3	0.4	0.5
Ever had bowel cancer screening	0.4	0.5	1.2	-0.2	-0.6	-0.7	-1.1	-0.5
Smoking status: Current	0.4	0.6	2.0	0.6	0.1	1.4	0.2	0.9
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.6	1.3	-0.5	0.5	-0.1	0.7
Leg fat mass (left)	0.4	1.7	5.7	2.4	-0.2	0.7	0.8	1.3
Bipolar Disorder (2018)	0.3	0.4	1.0	-0.7	0.8	0.0	1.0	0.2
Intelligence (Savage-Jansen 2018)	0.3	1.0	2.4	-1.3	-0.9	-0.3	-1.5	-0.5
Alzheimer’s Disease (in mother)	0.3	0.4	1.3	-0.4	0.6	0.4	0.4	1.1
Primary Biliary Cirrhosis	0.3	0.4	1.5	0.5	-0.5	0.0	0.2	1.2
Smoking Status	0.3	0.6	2.0	-0.5	-0.6	1.4	0.4	0.7
Fed-up feelings	0.3	0.5	0.7	-0.7	-0.8	-0.8	0.0	-0.8
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.5	0.7	0.5	0.1	0.6	0.7
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.4	-0.5	-1.2	0.3	-0.9	0.5
Had menopause	0.3	0.3	1.0	0.2	0.6	-0.5	0.4	1.0
Hip circumference	0.3	1.3	2.2	1.5	0.0	1.1	1.1	1.4
Pulse rate	0.3	0.5	1.6	1.3	0.5	0.6	-0.1	0.3
Happiness	0.3	0.3	1.2	1.1	-0.1	0.4	0.1	-0.4
Asthma	0.3	0.5	1.5	-1.2	0.3	0.8	0.7	0.3
Medication: Lansoprazole	0.3	0.3	0.6	0.6	-0.8	-0.3	-0.8	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	1.9	1.2	0.6	-0.5	1.4	0.0
Tense / ‘highly strung’	0.3	0.5	1.1	0.7	0.8	0.4	1.1	-0.2
Body fat percentage	0.3	1.3	4.6	2.1	0.2	0.7	0.7	1.1
Wheeze or whistling in the chest in last year	0.3	0.6	1.9	-0.0	-0.7	0.8	-0.0	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.8	0.9	0.3	-0.7	0.3	-0.1
Heart disease (mother)	0.3	0.4	1.2	0.4	-0.4	0.0	-0.7	-1.1
Whole body fat mass	0.3	1.3	3.9	2.0	-0.2	0.7	0.6	1.2
Leg fat mass (right)	0.3	1.3	3.4	1.8	-0.1	0.7	0.8	1.4
Comparative height size at age 10	0.3	1.7	4.1	-0.0	-2.0	-0.1	-1.8	-1.0
Commuting to job workplace: Walk	0.3	0.4	0.7	0.9	-0.3	-0.5	-0.6	-0.5
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.3	-1.2	-0.3	-0.2	-0.5	-0.3
Number of operations (self-reported)	0.3	0.5	1.5	0.2	0.3	0.3	0.8	1.2
Unable to work because of sickness or disability	0.3	0.4	0.8	0.9	-0.4	-0.9	0.1	-0.4
Supplements: Calcium	0.3	0.3	0.6	0.2	0.6	0.5	0.8	0.7
Basal cell carcinoma (self-reported)	0.3	0.3	0.8	0.0	0.6	-0.0	0.9	0.7
Worry (Nagel 2018)	0.2	0.5	1.1	-1.1	0.6	-0.3	0.4	-0.8
Fasting Glucose	0.2	0.2	0.7	0.1	0.8	0.1	0.0	0.5
Blood White Count	0.2	1.6	3.3	1.4	-1.8	-0.5	-1.1	-1.2
Waist Hip Ratio (WHR)	0.2	1.0	1.8	-0.1	-0.9	-1.3	-1.2	-0.8
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.6	0.2	-0.8	-0.8	0.1	-0.3
Vitamin and mineral supplements	0.2	0.3	1.0	0.5	-0.1	-0.6	1.0	0.1
Severe depression (siblings)	0.2	0.2	0.4	0.5	-0.1	0.4	0.6	0.6
Impedance of leg (right)	0.2	1.0	2.9	-1.7	0.3	0.2	-1.5	-0.1
Trunk fat percentage	0.2	0.8	3.4	1.8	-0.1	0.4	0.2	0.7
Impedance of leg (left)	0.2	0.9	3.9	-0.6	-0.1	-0.1	-2.0	-0.6
Trunk fat mass	0.2	0.9	3.3	1.8	-0.4	0.4	0.2	0.8
Alcohol usually taken with meals	0.2	0.3	0.9	-1.0	0.0	0.1	-0.8	-0.0
Weight	0.2	1.1	2.5	1.6	-0.4	0.5	1.0	1.2
Time employed in main current job	0.2	0.2	0.5	-0.7	-0.4	-0.5	0.3	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.8	0.9	-0.1	0.4	0.2	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.8	0.3	-0.4	-0.2	-0.9	0.1
Impedance of arm (left)	0.2	0.8	1.5	-1.2	0.8	0.3	-1.2	-0.2
Breastfed as a baby	0.2	0.3	0.8	-0.4	0.1	0.9	-0.4	0.5
Forced vital capacity (FVC), Best measure	0.2	0.6	1.9	1.4	-0.5	-0.5	0.6	-0.5
Migraine (self-reported)	0.2	0.2	0.4	0.6	-0.6	0.1	-0.5	-0.4
Medication: Omeprazole	0.2	0.2	0.7	0.6	-0.1	-0.4	0.8	-0.3
Number of full sisters	0.2	0.3	0.6	-0.4	-0.6	-0.4	-0.1	-0.8
Chest pain or discomfort	0.2	0.3	0.8	0.5	-0.9	-0.2	-0.7	-0.1
Smoking status: Previous	0.2	0.3	0.7	-0.5	-0.1	0.6	0.9	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.9	-0.1	-1.0	0.7	-0.6	0.4
Leg fat-free mass (right)	0.2	1.0	2.5	1.5	-1.6	-0.4	0.1	0.1
Asthma (self-reported)	0.2	0.4	1.0	-1.0	0.2	0.8	0.5	0.2
Leg predicted mass (right)	0.2	0.9	2.4	1.5	-1.5	-0.3	0.2	0.2
Miserableness	0.2	0.4	1.1	0.6	-1.1	0.5	-0.5	-0.1
Guilty feelings	0.2	0.3	0.9	0.6	0.2	1.0	0.1	0.4
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.7	-0.9	-0.4	-0.5	-0.5	-0.1
Pack years of smoking	0.2	0.2	0.7	0.6	0.1	-0.0	0.4	0.8
Impedance of whole body	0.2	1.0	2.7	-1.4	0.5	0.2	-1.6	-0.3
Arm predicted mass (left)	0.2	0.8	1.2	1.1	-0.7	0.2	1.0	1.1
Depressed Affect (Nagel 2018)	0.1	0.2	0.8	-0.2	-0.9	0.3	-0.1	-0.3
Depression (Nagel 2018)	0.1	0.1	0.3	-0.5	-0.3	0.5	0.4	-0.2
Neuroticism (Nagel 2018)	0.1	0.3	1.1	-0.4	-0.3	-0.5	0.0	-1.0
LDL Cholesterol	0.1	0.2	0.9	-1.0	0.0	0.0	0.5	0.2
Rheumatoid Arthritis	0.1	0.2	0.6	0.2	-0.5	-0.1	-0.3	-0.7
Neuroticism	0.1	0.3	1.2	-0.4	-0.1	-0.3	0.1	-1.1
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.2	0.4	-0.2	0.4	0.4	-0.2
Leg fat-free mass (left)	0.1	0.6	1.4	1.0	-1.2	-0.0	0.4	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.5	-0.2	0.0	0.7	0.6	0.0
Relative age voice broke	0.1	0.2	0.6	-0.8	0.4	-0.2	0.0	0.5
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	0.2	-0.5	0.3	-0.3	-0.1
Leg predicted mass (left)	0.1	0.6	1.5	1.1	-1.2	-0.1	0.4	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	0.6	-0.2	0.6	0.4	0.4
Forced vital capacity (FVC)	0.1	0.6	1.3	1.1	0.4	-0.2	1.2	0.3
Neuroticism score	0.1	0.3	1.0	-0.5	0.1	-0.3	0.1	-1.0
Impedance of arm (right)	0.1	0.6	1.5	-0.7	0.8	0.7	-1.2	-0.0
Trunk fat-free mass	0.1	0.4	1.8	0.2	-1.4	-0.3	0.2	0.4
Noisy workplace	0.1	0.1	0.2	-0.2	-0.1	-0.4	-0.4	0.0
Lung cancer (father)	0.1	0.1	0.3	0.1	0.4	-0.5	-0.2	-0.1
Trunk predicted mass	0.1	0.4	1.8	0.2	-1.3	-0.2	0.2	0.4
Blood clot in the leg (DVT)	0.1	0.2	0.4	-0.0	-0.4	-0.7	-0.3	-0.4
Arm fat-free mass (right)	0.1	0.6	1.8	0.8	-1.3	-0.8	0.3	0.2
Health satisfaction	0.1	0.1	0.3	0.2	-0.3	0.6	0.1	-0.1
Arm predicted mass (right)	0.1	0.6	1.8	0.7	-1.3	-0.6	0.3	0.3
Had major operations	0.1	0.1	0.2	-0.3	0.3	0.4	0.2	0.5
Whole body fat-free mass	0.1	0.6	2.0	0.7	-1.4	-0.3	0.2	0.4
Mood swings	0.1	0.2	0.7	0.5	0.0	0.9	0.2	-0.0
Loneliness, isolation	0.1	0.1	0.5	-0.7	0.1	-0.1	0.1	0.3
Whole body water mass	0.1	0.6	1.8	0.8	-1.4	-0.2	0.3	0.4
Basal metabolic rate	0.1	0.6	1.3	1.0	-1.1	-0.0	0.5	0.7
Arm fat-free mass (left)	0.1	0.6	1.5	0.9	-1.2	-0.3	0.5	0.6
Irritability	0.1	0.2	0.6	-0.2	0.3	-0.1	0.5	-0.8
Commuting to job workplace: Cycle	0.1	0.1	0.2	0.3	-0.5	-0.3	-0.3	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.4	-0.1	-0.4	-0.6	-0.1	-0.3

Hub : Genes

C20orf160

Models

Trait associations