[Hub]/) : Traits : High blood pressure :

chr4:17,104,059-18,507,692

Best TWAS P=1.77e-09 · Best GWAS P=4.25e-09 conditioned to 0.0182

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 5.4 -6.0 1.8e-09 -0.69 0.07 0.72 TRUE
2 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 -4.0 -5.3 1.2e-07 -0.66 0.05 0.57 FALSE
3 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 5.2 -5.2 1.8e-07 -0.79 0.03 0.89 FALSE
4 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 -4.3 -5.9 4.1e-09 -0.55 0.06 0.84 FALSE
5 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 5.2 5.2 2.2e-07 0.75 0.02 0.64 FALSE
6 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 -4.2 -5.4 7.4e-08 -0.55 0.21 0.65 FALSE