TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
High blood pressure
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chr6:42,586,058-44,034,691
Best TWAS P=8.11e-13 · Best GWAS P=2.63e-13 conditioned to 1
42.6M
42.8M
43M
43.2M
43.4M
43.6M
43.8M
44M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Lung Adenocarcinoma
ZNF318
0.05
0.06
lasso
3
0.05
1.1e-06
7.2
-7.2
8.1e-13
-0.99
0.00
1.00
TRUE
1
NTR
Blood
ZNF318
0.04
0.03
lasso
8
0.02
1.3e-08
6.3
6.3
2.4e-10
0.83
0.75
0.25
FALSE
2
YFS
Blood
ZNF318
0.10
0.08
lasso
5
0.10
5.6e-31
6.7
-5.5
5.1e-08
-0.86
0.12
0.88
FALSE
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
CRIP3
0.08
0.08
blup
34
0.07
1.0e-04
5.6
5.4
6.9e-08
0.67
0.12
0.76
FALSE
5
The Cancer Genome Atlas
Soft Tissue Sarcoma
ZNF318
0.04
0.02
blup
48
0.04
2.2e-03
5.7
5.4
7.6e-08
0.69
0.04
0.13
FALSE