Best TWAS P=8.11e-13 · Best GWAS P=2.63e-13 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | ZNF318 | 0.04 | 0.03 | lasso | 8 | 0.02 | 1.3e-08 | 6.3 | 6.3 | 2.4e-10 | 0.83 | 0.75 | 0.25 | FALSE |
| 2 | YFS | Blood | ZNF318 | 0.10 | 0.08 | lasso | 5 | 0.10 | 5.6e-31 | 6.7 | -5.5 | 5.1e-08 | -0.86 | 0.12 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CRIP3 | 0.08 | 0.08 | blup | 34 | 0.07 | 1.0e-04 | 5.6 | 5.4 | 6.9e-08 | 0.67 | 0.12 | 0.76 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF318 | 0.05 | 0.06 | lasso | 3 | 0.05 | 1.1e-06 | 7.2 | -7.2 | 8.1e-13 | -0.99 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZNF318 | 0.04 | 0.02 | blup | 48 | 0.04 | 2.2e-03 | 5.7 | 5.4 | 7.6e-08 | 0.69 | 0.04 | 0.13 | FALSE |