TWAS
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Usage
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Genes
Traits
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Traits
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High blood pressure
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chr7:76,506,844-77,966,572
Best TWAS P=1.1e-07 · Best GWAS P=7.97e-07 conditioned to 0.0676
76.6M
76.8M
77M
77.2M
77.4M
77.6M
77.8M
78M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Muscularis
PTPN12
0.34
0.17
enet
48
0.2
4.3e-12
-3.6
5.3
1.1e-07
-0.68
0.16
0.69
TRUE