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chr7:73,425,238-75,714,883

Best TWAS P=6.89e-09 · Best GWAS P=1.65e-08 conditioned to 0.378

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Esophagus Gastroesophageal Junction	PMS2P5	0.23	0.19	lasso	2	0.18	5.4e-07	5.6	-5.8	6.9e-09	-0.77	0.01	0.98	TRUE
3	GTEx	Adipose Subcutaneous	STAG3L1	0.30	0.24	enet	24	0.27	2.4e-22	-4.6	-5.3	9.2e-08	-0.12	0.00	0.98	TRUE
7	GTEx	Esophagus Mucosa	PMS2P5	0.14	0.03	lasso	4	0.04	1.7e-03	5.6	-5.7	1.2e-08	-0.79	0.01	0.87	FALSE
14	GTEx	Thyroid	GTF2IRD2B	0.03	0.04	lasso	1	0.03	1.9e-03	5.5	5.5	3.2e-08	0.96	0.01	0.82	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	PMS2P5	0.16	0.06	lasso	3	0.04	1.7e-02	5.6	-5.5	4.3e-08	-0.82	0.01	0.76	FALSE
9	GTEx	Heart Atrial Appendage	PMS2P5	0.12	0.03	lasso	5	0.07	3.8e-04	5.6	-5.5	4.8e-08	-0.75	0.01	0.59	FALSE
10	GTEx	Nerve Tibial	STAG3L2	0.36	0.09	enet	13	0.24	9.5e-17	3.6	-5.4	5.3e-08	-0.75	0.02	0.97	FALSE
2	GTEx	Adipose Subcutaneous	AC004166.6	0.09	0.08	lasso	2	0.07	3.9e-06	5.6	5.4	5.4e-08	0.85	0.01	0.99	FALSE
15	METSIM	Adipose	NCF1	0.05	0.03	blup	130	0.04	3.9e-07	5.6	5.4	6.8e-08	0.71	0.01	0.99	FALSE
12	GTEx	Testis	PMS2P5	0.22	0.13	lasso	2	0.13	3.1e-06	5.6	-5.4	7.6e-08	-0.75	0.01	0.96	FALSE
8	GTEx	Esophagus Muscularis	STAG3L2	0.23	0.09	enet	33	0.15	1.9e-09	3.6	-5.4	7.7e-08	-0.76	0.03	0.96	FALSE
11	GTEx	Skin Sun Exposed Lower leg	STAG3L2	0.15	0.05	enet	8	0.08	2.8e-07	3.6	-5.3	1.1e-07	-0.72	0.07	0.85	FALSE
4	GTEx	Adrenal Gland	STAG3L2	0.14	0.07	enet	3	0.11	1.2e-04	5.1	-5.3	1.5e-07	-0.92	0.02	0.77	FALSE
13	GTEx	Testis	STAG3L1	0.24	0.24	enet	14	0.27	1.4e-12	-4.6	-5.2	2.6e-07	-0.12	0.00	0.98	FALSE
1	GTEx	Adipose Subcutaneous	STAG3L2	0.16	0.03	enet	11	0.09	1.0e-07	3.6	-5.1	2.9e-07	-0.71	0.04	0.95	FALSE