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chr1:112,312,154-113,941,737

Best TWAS P=3.47e-17 · Best GWAS P=1.83e-20 conditioned to 5.77e-08

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Thyroid Carcinoma	RHOC	0.04	0.03	enet	9	0.04	1.4e-04	-7.6	-8.4	3.5e-17	-0.30	0.01	0.98	TRUE
11	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	WNT2B	0.05	0.02	blup	46	0.05	4.7e-04	-5.7	-7.7	1.9e-14	-0.30	0.06	0.10	TRUE
7	GTEx	Nerve Tibial	RP4-671G15.2	0.07	0.06	lasso	2	0.06	2.9e-05	-5.0	5.4	7.5e-08	0.17	0.94	0.00	TRUE
6	GTEx	Muscle Skeletal	WNT2B	0.06	0.02	lasso	7	0.03	9.4e-04	-5.7	-7.1	1.6e-12	-0.14	0.56	0.02	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CTTNBP2NL	0.04	0.00	blup	53	0.02	2.1e-03	-5.7	-6.3	3.3e-10	-0.27	0.03	0.19	FALSE
4	GTEx	Breast Mammary Tissue (Male)	WNT2B	0.18	0.07	lasso	6	0.05	2.3e-02	-5.7	-6.1	9.0e-10	-0.16	0.08	0.05	FALSE
2	GTEx	Adipose Subcutaneous	WNT2B	0.10	0.10	enet	19	0.06	1.2e-05	-4.8	-6.1	1.3e-09	-0.12	1.00	0.00	FALSE
3	GTEx	Artery Aorta	WNT2B	0.15	0.01	enet	7	0.01	1.0e-01	-5.8	-5.8	8.0e-09	-0.16	0.24	0.04	FALSE
5	GTEx	Breast Mammary Tissue (Female)	WNT2B	0.01	-0.01	enet	24	0.00	3.4e-01	1.3	-5.7	9.7e-09	-0.11	0.03	0.05	FALSE
1	CommonMind	Brain Pre-frontal Cortex	WNT2B	0.43	0.46	enet	44	0.47	7.4e-64	4.8	5.5	3.2e-08	0.33	1.00	0.00	FALSE
8	GTEx	Skin Sun Exposed Lower leg	RHOC	0.07	0.02	lasso	3	0.02	1.5e-02	-5.6	-5.5	3.4e-08	-0.16	0.54	0.02	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	CAPZA1	0.05	0.06	lasso	3	0.06	1.1e-07	-5.6	-5.5	4.1e-08	-0.16	1.00	0.00	FALSE