Best TWAS P=6.28e-09 · Best GWAS P=1.14e-08 conditioned to 0.00021
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | HRCT1 | 0.11 | 0.02 | enet | 22 | 0.05 | 4.4e-04 | 4.9 | 5.7 | 1.2e-08 | 0.60 | 0.03 | 0.84 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HRCT1 | 0.12 | 0.04 | blup | 49 | 0.11 | 5.2e-22 | -2.5 | 5.3 | 1.3e-07 | 0.35 | 0.97 | 0.01 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HRCT1 | 0.14 | 0.01 | blup | 49 | 0.09 | 2.7e-10 | -4.0 | 5.8 | 6.3e-09 | 0.40 | 0.82 | 0.13 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | HRCT1 | 0.09 | 0.02 | blup | 49 | 0.02 | 2.0e-03 | 2.6 | 5.8 | 7.6e-09 | 0.41 | 0.09 | 0.15 | FALSE |