TWAS
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Traits
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High blood pressure
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chr9:35,208,145-36,597,142
Best TWAS P=6.28e-09 · Best GWAS P=1.14e-08 conditioned to 0.00021
35.2M
35.4M
35.6M
35.8M
36M
36.2M
36.4M
36.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
HRCT1
0.14
0.01
blup
49
0.09
2.7e-10
-4.0
5.8
6.3e-09
0.40
0.82
0.13
TRUE
4
The Cancer Genome Atlas
Thyroid Carcinoma
HRCT1
0.09
0.02
blup
49
0.02
2.0e-03
2.6
5.8
7.6e-09
0.41
0.09
0.15
FALSE
1
GTEx
Esophagus Muscularis
HRCT1
0.11
0.02
enet
22
0.05
4.4e-04
4.9
5.7
1.2e-08
0.60
0.03
0.84
FALSE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
HRCT1
0.12
0.04
blup
49
0.11
5.2e-22
-2.5
5.3
1.3e-07
0.35
0.97
0.01
FALSE