Best TWAS P=1.94e-10 · Best GWAS P=7.95e-13 conditioned to 0.000124
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | NOC3L | 0.21 | 0.10 | lasso | 5 | 0.18 | 4.4e-07 | -1.0 | -5.2 | 2.6e-07 | -0.01 | 0.33 | 0.62 | FALSE |
| 2 | GTEx | Muscle Skeletal | NOC3L | 0.09 | 0.05 | enet | 7 | 0.05 | 7.5e-06 | -4.3 | -6.4 | 1.9e-10 | 0.69 | 0.10 | 0.88 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NOC3L | 0.05 | 0.01 | enet | 5 | 0.03 | 6.3e-04 | 5.3 | -5.3 | 1.2e-07 | 0.18 | 0.03 | 0.91 | FALSE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | NOC3L | 0.08 | 0.06 | lasso | 2 | 0.04 | 5.8e-03 | -6.0 | -6.0 | 1.7e-09 | 0.46 | 0.01 | 0.69 | FALSE |