TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
High blood pressure
:
←
→
chr10:95,379,543-96,818,402
Best TWAS P=1.94e-10 · Best GWAS P=7.95e-13 conditioned to 0.000124
95.4M
95.6M
95.8M
96M
96.2M
96.4M
96.6M
96.8M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Muscle Skeletal
NOC3L
0.09
0.05
enet
7
0.05
7.5e-06
-4.3
-6.4
1.9e-10
0.69
0.10
0.88
TRUE
4
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
NOC3L
0.08
0.06
lasso
2
0.04
5.8e-03
-6.0
-6.0
1.7e-09
0.46
0.01
0.69
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
NOC3L
0.05
0.01
enet
5
0.03
6.3e-04
5.3
-5.3
1.2e-07
0.18
0.03
0.91
FALSE
1
GTEx
Adrenal Gland
NOC3L
0.21
0.10
lasso
5
0.18
4.4e-07
-1.0
-5.2
2.6e-07
-0.01
0.33
0.62
FALSE