[Hub]/) : Traits : High blood pressure : ← →

chr10:103,313,599-105,850,787

Best TWAS P=1.25e-14 · Best GWAS P=2.96e-16 conditioned to 0.00657

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue (Female) SFXN2 0.09 -0.01 enet 7 0.01 1.9e-01 -4.5 5.1 2.9e-07 -0.50 0.05 0.05 FALSE
2 GTEx Breast Mammary Tissue (Female) CYP17A1-AS1 0.14 0.01 lasso 11 0.00 4.7e-01 -7.0 -5.2 1.5e-07 0.87 0.03 0.60 FALSE
3 GTEx Cells Transformed fibroblasts GBF1 0.07 0.00 enet 2 0.00 1.4e-01 -5.2 -5.2 1.6e-07 0.78 0.05 0.47 FALSE
4 GTEx Cells Transformed fibroblasts SUFU 0.07 0.04 lasso 3 0.04 3.5e-04 -7.0 -7.0 2.4e-12 0.83 0.38 0.16 FALSE
5 GTEx Testis NT5C2 0.20 0.03 lasso 8 0.08 2.8e-04 -7.0 -7.5 9.5e-14 0.86 0.04 0.91 FALSE
6 GTEx Testis CYP17A1-AS1 0.14 0.08 enet 5 0.10 2.3e-05 -7.0 7.1 1.3e-12 -0.97 0.05 0.93 FALSE
7 GTEx Thyroid WBP1L 0.26 0.10 enet 9 0.13 2.1e-10 -4.0 6.0 1.5e-09 -0.80 0.66 0.34 FALSE
8 ROSMAP Brain Pre-frontal Cortex CNNM2 0.11 0.08 lasso 3 0.07 2.2e-09 -7.4 -7.4 1.1e-13 0.99 0.02 0.98 FALSE
9 ROSMAP Brain Pre-frontal Cortex USMG5 0.04 0.03 lasso 9 0.03 1.6e-04 -3.2 5.7 1.3e-08 -0.64 0.04 0.94 FALSE
10 YFS Blood NT5C2 0.13 0.10 bslmm 382 0.11 7.3e-35 -8.0 -7.7 1.3e-14 0.94 0.01 0.99 TRUE
11 The Cancer Genome Atlas Colon Adenocarcinoma SFXN2 0.11 0.05 blup 47 0.05 7.2e-04 -4.2 5.2 2.1e-07 -0.63 0.13 0.59 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma AS3MT 0.05 0.02 blup 62 0.03 2.1e-03 3.1 -6.4 1.6e-10 0.72 0.02 0.32 FALSE