Best TWAS P=1.38e-11 · Best GWAS P=1.78e-11 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TNFSF18 | 0.24 | 0.22 | bslmm | 355 | 0.22 | 1.5e-26 | -6.4 | -6.5 | 8.4e-11 | 0.9 | 0.01 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TNFSF4 | 0.08 | 0.07 | lasso | 3 | 0.06 | 5.2e-07 | -6.7 | -6.8 | 1.4e-11 | 1.0 | 0.00 | 1.00 | TRUE |