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chr9:135,883,620-137,326,408

Best TWAS P=2.85e-16 · Best GWAS P=1.97e-18 conditioned to 1.94e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABO	0.23	0.23	lasso	2	0.24	2.2e-11	-8.2	-8.2	2.8e-16	0.53	0.00	1.00	TRUE
15	The Cancer Genome Atlas	Rectum Adenocarcinoma	ABO	0.48	0.23	enet	10	0.27	4.7e-07	-8.1	-8.1	5.5e-16	0.65	0.00	0.98	FALSE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	ABO	0.21	0.25	lasso	5	0.25	2.1e-29	-7.7	-7.8	5.2e-15	0.59	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ABO	0.28	0.22	lasso	8	0.22	1.2e-14	-7.7	-7.8	8.0e-15	0.63	0.01	0.99	FALSE
2	The Cancer Genome Atlas	Breast Invasive Carcinoma	ABO	0.07	0.08	lasso	3	0.08	5.0e-16	-7.7	-7.7	1.1e-14	0.63	0.04	0.96	FALSE
4	The Cancer Genome Atlas	Esophageal Carcinoma	ABO	0.27	0.13	lasso	2	0.11	1.8e-04	-7.8	-7.7	1.1e-14	0.63	0.01	0.96	FALSE
7	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ABO	0.31	0.38	lasso	5	0.42	3.1e-26	-8.2	-7.7	1.4e-14	0.54	0.00	1.00	FALSE
14	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ABO	0.23	0.23	lasso	3	0.23	2.0e-09	-7.8	-7.7	1.6e-14	0.61	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Brain Lower Grade Glioma	ABO	0.26	0.23	enet	10	0.26	6.0e-29	-7.7	-7.5	7.9e-14	0.66	0.05	0.95	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	ABO	0.44	0.57	enet	18	0.60	1.9e-73	-7.7	-7.3	3.7e-13	0.51	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ABO	0.23	0.21	lasso	5	0.20	6.7e-09	-8.2	-7.2	4.9e-13	0.49	0.00	1.00	FALSE
20	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	ABO	0.23	0.07	blup	44	0.12	4.3e-04	-8.2	-7.0	2.4e-12	0.62	0.00	0.80	FALSE
3	The Cancer Genome Atlas	Colon Adenocarcinoma	ABO	0.27	0.31	blup	43	0.33	2.1e-19	-7.8	-6.7	2.8e-11	0.52	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ABO	0.41	0.17	enet	12	0.25	3.0e-09	5.1	-6.5	9.2e-11	0.37	0.04	0.96	FALSE
16	The Cancer Genome Atlas	Soft Tissue Sarcoma	ABO	0.32	0.18	enet	10	0.20	2.3e-12	-7.7	-6.2	7.2e-10	0.49	0.00	1.00	FALSE
17	The Cancer Genome Atlas	Stomach Adenocarcinoma	ABO	0.20	0.10	blup	42	0.18	5.8e-13	-7.7	-6.0	1.9e-09	0.45	0.00	1.00	FALSE
11	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ABO	0.08	0.06	blup	43	0.09	1.7e-10	-7.7	-5.8	6.7e-09	0.40	0.00	1.00	FALSE
5	The Cancer Genome Atlas	Glioblastoma Multiforme	ABO	0.18	0.01	blup	42	0.07	3.0e-03	-7.8	-5.3	1.1e-07	0.36	0.00	0.75	FALSE
1	GTEx	Breast Mammary Tissue	AL590710.1	0.31	0.11	lasso	7	0.12	1.3e-06	2.7	-5.3	1.4e-07	0.21	0.56	0.04	FALSE
6	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ABO	0.11	0.08	blup	43	0.12	2.5e-13	-7.8	-5.3	1.4e-07	0.42	0.01	0.99	FALSE