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chr10:5,238,196-7,317,647
Best TWAS P=8.76e-10 · Best GWAS P=4.73e-22 conditioned to 1.92e-14
5.5M
6M
6.5M
7M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Stomach Adenocarcinoma
IL2RA
0.09
0.03
enet
8
0.05
9.8e-05
6.4
6.1
8.8e-10
-0.20
0.09
0.06
TRUE
2
METSIM
Adipose
IL2RA
0.07
0.02
lasso
3
0.02
1.0e-03
-5.1
-5.7
1.2e-08
0.14
0.54
0.02
TRUE
3
YFS
Blood
PRKCQ
0.04
0.03
lasso
3
0.02
9.7e-09
-5.7
5.5
3.9e-08
-0.04
1.00
0.00
TRUE
1
GTEx
Nerve Tibial
FBXO18
0.10
0.00
lasso
5
0.00
5.5e-01
7.0
5.7
1.1e-08
-0.06
0.17
0.05
FALSE