Best TWAS P=4.35e-16 · Best GWAS P=2.19e-17 conditioned to 0.000879
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | PLRG1 | 0.23 | 0.13 | lasso | 7 | 0.19 | 6.8e-13 | 6.3 | -8.1 | 4.4e-16 | -0.80 | 0.02 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FGA | 0.12 | 0.07 | lasso | 3 | 0.06 | 1.5e-07 | 5.5 | 5.8 | 8.3e-09 | 0.65 | 0.98 | 0.01 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FGB | 0.14 | 0.09 | lasso | 2 | 0.09 | 3.3e-10 | 6.3 | 6.3 | 2.6e-10 | 0.66 | 1.00 | 0.00 | FALSE |