[Hub]/) : Traits : Blood clot in the leg (DVT) :

chr1:168,375,973-170,514,229

Best TWAS P=6.49e-17 · Best GWAS P=1.1e-172 conditioned to 1.17e-88

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ATP1B1 0.12 0.03 enet 12 0.04 2.0e-03 7.252 -6.0 1.5e-09 -0.12 0.46 0.03 TRUE
2 GTEx Artery Tibial AL021068.1 0.07 0.00 enet 31 0.00 1.8e-01 -0.015 -5.4 6.7e-08 -0.17 0.09 0.07 FALSE
3 GTEx Skin Not Sun Exposed Suprapubic C1orf112 0.15 -0.01 enet 36 0.08 3.7e-05 0.824 5.9 4.6e-09 0.15 0.13 0.04 TRUE
4 GTEx Stomach ATP1B1 0.13 0.01 lasso 5 0.04 4.3e-03 0.101 -7.0 2.6e-12 -0.23 0.22 0.06 TRUE
5 GTEx Vagina NME7 0.47 0.16 lasso 9 0.17 9.9e-05 4.059 -7.9 2.7e-15 -0.26 0.30 0.05 TRUE
6 The Cancer Genome Atlas Glioblastoma Multiforme C1orf114 0.26 0.04 lasso 8 0.07 4.8e-03 15.874 -7.6 2.2e-14 -0.28 0.01 0.06 FALSE
7 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NME7 0.16 0.08 blup 150 0.07 1.0e-08 -0.662 -5.2 2.6e-07 -0.17 1.00 0.00 TRUE
8 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC19A2 0.06 0.00 enet 9 0.00 1.4e-01 -1.611 -8.4 6.5e-17 -0.24 0.02 0.04 TRUE