Best TWAS P=3.66e-08 · Best GWAS P=1.9e-07 conditioned to 0.353
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Glioblastoma Multiforme | RGS14 | 0.22 | 0.24 | blup | 39 | 0.27 | 6.9e-09 | 4.7 | -5.5 | 3.7e-08 | -0.86 | 0.02 | 0.97 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | RGS14 | 0.26 | 0.18 | lasso | 5 | 0.19 | 4.5e-18 | 5.0 | -5.1 | 3.1e-07 | -0.73 | 0.02 | 0.98 | FALSE |