[Hub]/) : Traits : Hayfever, allergic rhinitis or eczema :

chr6:25,266,147-26,689,223

Best TWAS P=6.92e-13 · Best GWAS P=1.17e-12 conditioned to 0.0533

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous U91328.19 0.40 0.46 lasso 8 0.46 4.2e-41 6.1 -6.1 1.2e-09 -0.87 0.62 0.38 FALSE
2 GTEx Adipose Visceral Omentum U91328.19 0.21 0.25 lasso 8 0.27 3.7e-14 6.1 -6.5 8.6e-11 -0.93 0.02 0.98 FALSE
3 GTEx Adrenal Gland U91328.19 0.28 0.12 lasso 10 0.14 1.3e-05 4.7 -6.4 1.7e-10 -0.86 0.05 0.95 FALSE
4 GTEx Artery Aorta U91328.19 0.32 0.24 lasso 7 0.25 8.3e-14 7.0 -6.9 4.2e-12 -0.94 0.01 0.99 FALSE
5 GTEx Artery Tibial U91328.19 0.26 0.32 lasso 5 0.31 1.6e-24 6.1 -6.2 7.3e-10 -0.88 0.42 0.58 FALSE
6 GTEx Brain Caudate basal ganglia U91328.19 0.23 0.16 lasso 10 0.16 3.1e-05 5.7 -6.5 7.8e-11 -0.75 0.20 0.72 FALSE
7 GTEx Brain Cortex U91328.19 0.36 0.14 lasso 10 0.15 7.1e-05 5.6 -5.3 1.4e-07 -0.77 0.06 0.91 FALSE
8 GTEx Brain Frontal Cortex BA9 U91328.19 0.17 0.16 lasso 4 0.18 1.8e-05 5.6 -5.8 7.3e-09 -0.83 0.04 0.92 FALSE
9 GTEx Breast Mammary Tissue U91328.19 0.38 0.39 lasso 5 0.38 2.2e-20 6.1 -6.2 6.3e-10 -0.87 0.32 0.68 FALSE
10 GTEx Breast Mammary Tissue (Female) U91328.19 0.39 0.27 lasso 6 0.23 1.4e-07 6.1 -6.3 2.9e-10 -0.85 0.04 0.95 FALSE
11 GTEx Cells Transformed fibroblasts U91328.19 0.58 0.62 lasso 8 0.60 6.2e-56 6.1 -6.2 5.2e-10 -0.87 0.59 0.41 FALSE
12 GTEx Esophagus Gastroesophageal Junction U91328.20 0.16 0.13 enet 16 0.13 2.0e-05 5.0 -5.2 2.2e-07 -0.60 0.14 0.69 FALSE
13 GTEx Esophagus Gastroesophageal Junction U91328.19 0.28 0.07 lasso 7 0.21 4.3e-08 5.6 -5.5 4.4e-08 -0.76 0.02 0.97 FALSE
14 GTEx Esophagus Mucosa U91328.19 0.45 0.42 lasso 7 0.44 6.3e-32 6.1 -6.3 4.1e-10 -0.90 0.13 0.87 FALSE
15 GTEx Esophagus Muscularis TRIM38 0.06 0.04 lasso 4 0.02 1.7e-02 7.0 -6.5 8.3e-11 -0.85 0.08 0.85 FALSE
16 GTEx Esophagus Muscularis U91328.19 0.36 0.30 lasso 10 0.30 1.7e-18 7.0 -6.5 6.3e-11 -0.96 0.02 0.98 FALSE
17 GTEx Heart Atrial Appendage U91328.19 0.25 0.17 enet 6 0.13 2.0e-06 6.1 -6.5 8.1e-11 -0.92 0.02 0.98 FALSE
18 GTEx Heart Left Ventricle U91328.19 0.20 0.18 lasso 5 0.15 2.4e-08 6.1 -6.2 4.3e-10 -0.86 0.10 0.90 FALSE
19 GTEx Lung U91328.19 0.20 0.22 enet 15 0.24 2.9e-18 7.1 -7.0 2.4e-12 -0.95 0.01 0.99 FALSE
20 GTEx Muscle Skeletal U91328.19 0.28 0.26 enet 15 0.32 1.3e-31 6.1 -5.8 5.0e-09 -0.80 0.49 0.51 FALSE
21 GTEx Nerve Tibial U91328.19 0.46 0.38 lasso 10 0.36 1.4e-26 6.1 -6.1 1.3e-09 -0.87 0.63 0.37 FALSE
22 GTEx Ovary U91328.19 0.37 0.17 enet 18 0.34 4.7e-09 5.6 -6.5 8.3e-11 -0.84 0.01 0.98 FALSE
23 GTEx Prostate U91328.19 0.30 0.39 lasso 2 0.37 3.0e-10 6.1 -6.1 9.5e-10 -0.87 0.04 0.96 FALSE
24 GTEx Skin Not Sun Exposed Suprapubic U91328.19 0.39 0.37 lasso 11 0.34 2.4e-19 6.1 -6.6 5.6e-11 -0.91 0.05 0.95 FALSE
25 GTEx Skin Sun Exposed Lower leg U91328.19 0.29 0.34 lasso 6 0.34 5.6e-29 6.1 -6.4 1.6e-10 -0.86 0.54 0.46 FALSE
26 GTEx Thyroid U91328.19 0.21 0.17 lasso 5 0.17 6.4e-13 6.1 -6.0 1.8e-09 -0.85 0.11 0.89 FALSE
27 GTEx Uterus U91328.19 0.38 0.05 enet 21 0.04 6.2e-02 7.1 -7.2 6.9e-13 -0.85 0.02 0.91 TRUE
28 GTEx Vagina U91328.19 0.45 0.27 lasso 4 0.26 9.4e-07 6.1 -6.1 8.4e-10 -0.85 0.03 0.95 FALSE
29 METSIM Adipose U91328.19 0.19 0.24 lasso 23 0.25 1.7e-36 6.1 -6.4 2.2e-10 -0.85 0.70 0.30 FALSE