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chr6:134,905,567-136,516,257

Best TWAS P=5.25e-10 · Best GWAS P=2.55e-10 conditioned to 0.0333

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	AHI1	0.11	0.03	enet	16	0.09	1.8e-07	5.4	-5.7	1.2e-08	-0.80	0.04	0.95	FALSE
2	GTEx	Brain Cortex	RP3-388E23.2	0.28	0.16	enet	13	0.19	5.8e-06	2.1	-5.2	1.7e-07	-0.76	0.12	0.78	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	AHI1	0.38	0.24	enet	19	0.23	5.4e-08	6.1	-5.7	1.2e-08	-0.83	0.01	0.99	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	RP3-388E23.2	0.26	0.05	lasso	6	0.02	7.1e-02	6.1	-6.1	1.1e-09	-0.90	0.01	0.94	FALSE
5	GTEx	Cells Transformed fibroblasts	AHI1	0.44	0.21	enet	22	0.32	4.4e-24	5.7	-5.5	3.2e-08	-0.75	0.05	0.95	FALSE
6	GTEx	Esophagus Mucosa	AHI1	0.30	0.24	lasso	8	0.32	4.6e-22	6.1	-5.6	1.7e-08	-0.78	0.01	0.99	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	AHI1	0.41	0.31	lasso	7	0.40	9.1e-24	6.1	-5.8	7.8e-09	-0.81	0.01	0.99	FALSE
8	GTEx	Skin Sun Exposed Lower leg	AHI1	0.33	0.22	enet	14	0.34	1.0e-28	2.1	-5.1	3.1e-07	-0.73	0.44	0.56	FALSE
9	GTEx	Small Intestine Terminal Ileum	AHI1	0.51	0.01	enet	19	0.06	2.0e-02	6.1	-5.3	1.5e-07	-0.72	0.02	0.70	FALSE
10	GTEx	Spleen	AHI1	0.31	0.21	lasso	3	0.38	8.6e-11	5.2	-5.6	1.6e-08	-0.72	0.02	0.94	FALSE
11	METSIM	Adipose	AHI1	0.25	0.22	lasso	7	0.28	1.1e-42	6.1	-5.9	4.2e-09	-0.79	0.01	0.99	FALSE
12	NTR	Blood	AHI1	0.11	0.14	lasso	6	0.15	3.2e-47	6.1	-6.1	8.1e-10	-0.78	0.01	0.99	FALSE
13	YFS	Blood	AHI1	0.24	0.30	bslmm	414	0.33	1.4e-110	6.1	-5.8	6.2e-09	-0.80	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	AHI1	0.06	0.02	lasso	7	0.02	1.3e-04	6.1	-6.0	2.5e-09	-0.78	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	AHI1	0.06	0.08	blup	73	0.06	1.1e-03	6.1	-5.3	1.1e-07	-0.80	0.01	0.96	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AHI1	0.18	0.19	lasso	4	0.18	6.4e-20	6.1	-6.2	5.3e-10	-0.82	0.01	0.99	TRUE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	AHI1	0.03	0.02	enet	7	0.01	8.1e-03	6.1	-5.5	2.9e-08	-0.80	0.01	0.94	FALSE
18	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	AHI1	0.13	0.16	lasso	3	0.16	1.2e-17	6.1	-6.2	5.4e-10	-0.82	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AHI1	0.05	0.05	lasso	1	0.04	1.5e-03	6.1	-6.1	1.0e-09	-0.82	0.01	0.92	FALSE
20	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AHI1	0.36	0.30	lasso	3	0.29	1.0e-10	6.1	-6.2	6.9e-10	-0.84	0.01	0.99	FALSE