Best TWAS P=5.45e-08 · Best GWAS P=1.29e-06 conditioned to 0.958
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | MRPS33 | 0.16 | 0.09 | lasso | 8 | 0.13 | 3.4e-10 | -4.3 | 5.1 | 2.7e-07 | -0.89 | 0.02 | 0.96 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | MRPS33 | 0.04 | 0.00 | blup | 28 | 0.01 | 6.6e-02 | -4.3 | 5.4 | 5.4e-08 | -0.89 | 0.00 | 0.46 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MRPS33 | 0.05 | 0.02 | enet | 8 | 0.01 | 1.2e-02 | -4.8 | 5.3 | 1.4e-07 | -0.85 | 0.00 | 0.71 | FALSE |