TWAS
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chr7:140,009,905-141,413,051
Best TWAS P=5.45e-08 · Best GWAS P=1.29e-06 conditioned to 0.958
140M
140.2M
140.4M
140.6M
140.8M
141M
141.2M
141.4M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
MRPS33
0.04
0.00
blup
28
0.01
6.6e-02
-4.3
5.4
5.4e-08
-0.89
0.00
0.46
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
MRPS33
0.05
0.02
enet
8
0.01
1.2e-02
-4.8
5.3
1.4e-07
-0.85
0.00
0.71
FALSE
1
GTEx
Cells Transformed fibroblasts
MRPS33
0.16
0.09
lasso
8
0.13
3.4e-10
-4.3
5.1
2.7e-07
-0.89
0.02
0.96
FALSE