[Hub]/) : Traits : Hayfever, allergic rhinitis or eczema :

chr9:126,321,003-127,872,298

Best TWAS P=7.41e-10 · Best GWAS P=1.05e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PSMB7 0.08 0.04 lasso 6 0.04 3.4e-04 5.7 -5.3 1.1e-07 -0.89 0.13 0.85 FALSE
2 GTEx Colon Sigmoid PSMB7 0.15 0.10 lasso 3 0.09 3.3e-04 5.8 -5.7 1.4e-08 -0.95 0.04 0.93 FALSE
3 GTEx Nerve Tibial NEK6 0.11 0.02 enet 40 0.03 3.9e-03 4.7 -5.3 1.4e-07 -0.40 0.05 0.62 FALSE
4 GTEx Thyroid NEK6 0.20 0.21 lasso 4 0.20 1.3e-15 6.1 -6.2 7.4e-10 -0.96 0.00 1.00 TRUE
5 The Cancer Genome Atlas Breast Invasive Carcinoma NEK6 0.04 0.02 blup 87 0.02 2.5e-05 -4.8 -5.3 1.5e-07 -0.53 0.41 0.55 FALSE
6 The Cancer Genome Atlas Prostate Adenocarcinoma NEK6 0.06 0.01 blup 87 0.04 1.0e-04 -4.8 -6.1 1.2e-09 -0.72 0.01 0.97 FALSE