TWAS
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Traits
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Traits
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Hayfever, allergic rhinitis or eczema
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chr13:72,661,114-74,288,499
Best TWAS P=4.1e-09 · Best GWAS P=4.03e-11 conditioned to 2.31e-05
72.6M
72.8M
73M
73.2M
73.4M
73.6M
73.8M
74M
74.2M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Cortex
PIBF1
0.25
0.23
lasso
3
0.21
2.1e-06
-5.5
5.9
4.1e-09
-0.50
0.24
0.63
TRUE
2
GTEx
Skin Not Sun Exposed Suprapubic
PIBF1
0.19
0.05
lasso
5
0.04
3.1e-03
-5.5
5.4
5.6e-08
-0.45
0.23
0.36
FALSE