Best TWAS P=3.26e-17 · Best GWAS P=4.83e-13 conditioned to 0.00664
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | FOXO1 | 0.02 | 0.02 | lasso | 4 | 0.02 | 3.3e-08 | -5.7 | 8.4 | 3.3e-17 | 0.60 | 0.03 | 0.96 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | SUGT1L1 | 0.12 | 0.02 | blup | 58 | 0.05 | 1.4e-06 | 6.0 | 5.2 | 1.5e-07 | 0.66 | 0.00 | 1.00 | FALSE |