Best TWAS P=4.75e-09 · Best GWAS P=6.3e-08 conditioned to 0.318
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | MGRN1 | 0.32 | 0.10 | enet | 18 | 0.33 | 3.6e-18 | -2.8 | -5.9 | 4.8e-09 | -0.56 | 0.27 | 0.66 | TRUE |
| 2 | GTEx | Muscle Skeletal | MGRN1 | 0.16 | 0.06 | lasso | 7 | 0.15 | 1.1e-14 | -2.9 | -5.5 | 4.0e-08 | -0.51 | 0.47 | 0.41 | FALSE |
| 3 | METSIM | Adipose | NUDT16L1 | 0.06 | 0.03 | bslmm | 392 | 0.04 | 2.2e-06 | 4.4 | 5.6 | 1.7e-08 | 0.84 | 0.01 | 0.98 | TRUE |