Best TWAS P=2.14e-07 · Best GWAS P=5.33e-08 conditioned to 0.0577
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ATG7 | 0.07 | 0.07 | lasso | 3 | 0.07 | 3.3e-09 | 4.7 | -5.1 | 3.1e-07 | -0.82 | 0.09 | 0.90 | FALSE |
2 | GTEx | Adipose Visceral Omentum | ATG7 | 0.18 | 0.06 | lasso | 4 | 0.06 | 2.9e-04 | 4.7 | -5.1 | 3.1e-07 | -0.81 | 0.11 | 0.86 | FALSE |
3 | GTEx | Muscle Skeletal | ATG7 | 0.06 | 0.02 | lasso | 4 | 0.03 | 8.6e-04 | 5.2 | -5.2 | 2.1e-07 | -0.86 | 0.04 | 0.94 | TRUE |