TWAS hub - ATG7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0730	0.0210	9.3e-07	0.065	0.064	0.072	0.068	0.073	2.2e-08	2.8e-08	3.6e-09	1.2e-08	3.3e-09
2	GTEx	Adipose Subcutaneous	0.0990	0.0400	3.7e-03	0.008	NA	0.029	NA	0.020	6.2e-02	NA	2.0e-03	NA	9.0e-03
3	GTEx	Adipose Visceral Omentum	0.1820	0.0600	3.5e-04	0.062	NA	0.039	NA	0.065	3.8e-04	NA	4.3e-03	NA	2.9e-04
4	GTEx	Brain Hypothalamus	0.2540	0.1060	7.2e-03	-0.008	NA	-0.008	NA	-0.013	5.5e-01	NA	5.6e-01	NA	9.3e-01
5	GTEx	Cells EBV-transformed lymphocytes	0.3950	0.1010	5.9e-05	0.124	NA	0.150	NA	0.170	8.0e-05	NA	1.3e-05	NA	3.4e-06
6	GTEx	Cells Transformed fibroblasts	0.2620	0.0540	5.1e-09	0.102	NA	0.172	NA	0.169	4.6e-08	NA	6.8e-13	NA	1.1e-12
7	GTEx	Esophagus Mucosa	0.1190	0.0440	1.2e-03	0.039	NA	0.052	NA	0.050	1.2e-03	NA	2.2e-04	NA	2.9e-04
8	GTEx	Muscle Skeletal	0.0585	0.0236	2.7e-03	0.022	NA	0.003	NA	0.028	3.0e-03	NA	1.3e-01	NA	8.6e-04
9	GTEx	Nerve Tibial	0.1097	0.0441	4.6e-03	0.038	NA	0.025	NA	0.039	1.0e-03	NA	6.4e-03	NA	8.9e-04
10	GTEx	Skin Not Sun Exposed Suprapubic	0.1040	0.0440	5.1e-03	0.059	NA	0.043	NA	0.037	3.7e-04	NA	2.1e-03	NA	4.3e-03
11	GTEx	Thyroid	0.1100	0.0440	3.2e-03	0.016	NA	0.001	NA	0.020	2.1e-02	NA	2.6e-01	NA	1.1e-02
12	METSIM	Adipose	0.0582	0.0220	1.2e-03	0.011	0.007	0.002	0.008	0.001	7.3e-03	2.5e-02	1.4e-01	2.1e-02	1.9e-01
13	ROSMAP	Brain Pre-frontal Cortex	0.0601	0.0228	2.4e-04	0.053	0.027	0.040	0.031	0.044	1.9e-07	1.9e-04	6.4e-06	6.1e-05	2.4e-06
14	YFS	Blood	0.0997	0.0218	8.2e-15	0.060	0.065	0.061	0.083	0.063	6.5e-19	2.9e-20	4.3e-19	1.2e-25	9.0e-20
15	TCGA	Bladder Urothelial Carcinoma	0.0580	0.0360	5.3e-03	0.012	0.010	0.016	NA	0.017	3.3e-02	4.1e-02	1.5e-02	NA	1.2e-02
16	TCGA	Breast Invasive Carcinoma	0.0939	0.0326	7.4e-08	0.003	0.024	0.015	NA	0.014	7.9e-02	7.4e-06	3.6e-04	NA	5.8e-04
17	TCGA	Head and Neck Squamous Cell Carcinoma	0.0473	0.0287	1.2e-03	0.048	0.018	0.020	NA	0.028	3.9e-06	3.4e-03	2.3e-03	NA	3.2e-04
18	TCGA	Brain Lower Grade Glioma	0.0661	0.0292	7.1e-04	0.003	0.030	0.022	NA	0.017	1.3e-01	1.9e-04	1.3e-03	NA	4.7e-03
19	TCGA	Lung Adenocarcinoma	0.0890	0.0377	3.8e-04	0.037	0.029	0.013	NA	0.018	3.6e-05	2.1e-04	1.1e-02	NA	3.1e-03
20	TCGA	Testicular Germ Cell Tumors	0.4200	0.1290	5.7e-03	0.080	0.019	0.002	NA	0.053	8.8e-04	6.8e-02	2.6e-01	NA	6.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20
Medication for cholesterol	8.7	13.2	26.9	-5.1	-4.6	-5.1	-2.7	-3.7	-4.5	0.2	-5.2	-3.2	2.6	-1.0	-2.8	-4.7	-2.8	-4.9	2.3	-5.0	-3.5	-0.3	0.5
Comparative body size at age 10	7.8	21.5	59.6	-7.7	-3.0	-6.6	-4.1	-4.7	-5.0	0.9	-7.6	-2.2	4.0	1.4	-4.2	-7.3	-2.1	-4.8	2.5	-6.5	-5.1	0.3	-0.1
Relative age of first facial hair	6.7	13.7	31.1	5.2	4.5	4.4	2.6	4.8	3.3	-0.3	5.6	1.2	-5.5	-1.5	2.5	3.9	2.5	2.0	-5.5	3.5	0.8	-3.9	-3.2
Systolic Blood Pressure	6.4	32.2	77.3	8.6	5.5	8.3	4.3	6.2	6.8	-0.5	8.8	4.0	-4.8	-0.3	4.1	8.0	3.2	7.0	-2.5	7.9	6.6	0.2	-0.0
Medication: Blood pressure	6.2	11.7	23.7	4.7	3.6	4.6	4.1	3.3	4.0	-1.0	4.6	2.5	-2.8	0.4	1.7	4.4	2.1	4.9	-0.5	4.8	4.6	1.7	0.9
Systolic blood pressure, automated reading	5.4	15.7	36.0	6.0	3.8	5.6	3.5	4.1	4.6	-0.9	5.9	2.7	-3.9	-0.8	2.2	5.7	1.8	4.7	-1.3	5.6	5.3	0.2	0.8
Hypertension (Self-reported)	5.4	15.1	32.9	5.6	4.4	5.3	3.6	3.6	4.6	-0.9	5.7	2.8	-4.6	-0.3	1.5	4.7	1.3	5.4	-1.1	5.6	5.0	0.8	0.8
High blood pressure	5.0	13.8	30.1	5.3	4.2	5.1	3.1	3.3	4.4	-0.8	5.5	2.8	-4.4	-0.1	1.3	4.4	1.2	5.3	-0.7	5.3	5.0	1.1	1.0
Vascular/heart problems diagnosed by doctor	4.6	12.6	28.5	-5.1	-4.3	-4.9	-3.0	-3.6	-4.1	0.8	-5.3	-2.7	4.2	-0.0	-1.3	-3.9	-1.3	-5.0	1.2	-4.9	-4.5	-0.8	-0.6
Medication: Bendroflumethiazide	4.5	6.8	15.6	3.4	3.0	3.7	1.9	2.9	3.3	0.6	3.5	2.8	-1.9	1.4	1.1	3.1	1.5	4.0	-0.9	3.4	3.1	1.2	0.0
Cardiovascular Disease	4.1	13.4	35.5	5.3	4.9	4.9	2.3	4.1	3.9	-0.3	6.0	2.5	-4.4	0.1	2.3	4.6	1.2	4.8	-2.9	4.8	3.3	-0.8	-0.3
Mouth/teeth dental problems: Dentures	3.9	6.6	15.6	2.5	2.5	3.3	1.8	2.7	3.7	2.2	2.9	3.6	0.8	2.9	1.9	1.6	1.8	4.0	0.2	3.1	2.9	2.4	-0.1
Tinnitus: Yes, now most or all of the time	3.9	4.5	10.3	3.1	-0.1	3.0	3.2	2.1	2.6	-0.4	2.5	1.6	-1.7	0.6	2.6	3.1	1.1	2.5	0.2	3.1	2.3	0.1	0.3
Hearing difficulty/problems with background noise	3.7	6.0	23.6	3.1	1.8	2.0	2.9	1.6	1.4	-4.0	2.7	-0.7	-4.9	-3.1	-1.1	3.3	0.0	1.9	-0.2	2.7	2.6	-0.4	1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.7	4.3	7.9	2.8	1.6	2.6	1.9	2.6	2.6	1.1	2.8	2.4	-0.6	1.4	1.7	2.7	1.6	2.7	-0.1	2.8	2.4	0.6	0.6
Health satisfaction	3.6	4.6	8.4	2.5	2.4	2.8	2.7	2.4	2.9	0.4	2.8	2.4	-0.7	0.9	0.6	2.1	1.8	2.9	-0.4	2.9	2.9	1.6	0.9
Heel bone mineral density (BMD) T-score, automated (right)	3.5	8.1	19.7	-4.4	-3.7	-3.7	-3.2	-3.1	-2.8	1.0	-3.6	-0.9	2.9	1.7	-2.0	-4.4	-1.9	-2.5	0.4	-4.1	-2.9	-0.4	-1.3
Serious illness, injury or assault to yourself	3.3	3.9	9.4	2.0	3.1	2.3	2.3	2.6	2.4	2.5	2.1	2.3	0.3	1.7	1.3	1.3	2.6	1.7	-2.0	1.9	1.1	-0.4	-1.1
Impedance of arm (left)	3.3	15.3	30.8	3.1	4.7	4.6	1.4	4.2	5.0	5.2	3.9	5.5	1.8	5.2	4.6	2.5	4.9	4.1	-3.7	3.0	0.6	0.3	-3.6
Birth weight of first child	3.3	6.0	15.2	-3.6	-2.6	-3.9	-2.0	-2.8	-3.1	-1.0	-3.8	-2.4	1.3	-1.0	-1.3	-3.0	-1.8	-2.7	1.6	-3.0	-1.8	0.8	2.0
Impedance of leg (right)	3.2	15.7	28.7	4.5	4.2	5.2	1.0	4.2	5.3	4.2	4.4	5.4	0.6	4.4	5.2	3.8	3.7	4.9	-1.9	4.4	2.4	1.0	-2.8
Impedance of whole body	3.2	16.3	32.9	3.6	4.5	5.0	0.8	4.3	5.3	5.2	4.2	5.7	1.8	5.3	5.1	2.8	4.5	4.6	-3.0	3.6	1.3	0.7	-3.7
Impedance of leg (left)	3.1	15.2	27.6	4.2	4.3	5.1	0.6	4.1	5.2	4.3	4.3	5.2	1.0	4.5	4.9	3.4	3.9	4.7	-2.2	4.1	2.1	0.8	-3.2
Mean Putamen Volume	3.0	3.4	7.2	1.9	2.4	2.0	2.1	2.7	2.4	1.4	1.9	2.5	-1.1	1.9	1.6	1.9	2.0	2.1	-0.8	2.2	1.1	0.1	-0.3
Medication: Atenolol	3.0	3.8	9.0	3.0	1.9	2.2	2.6	1.5	1.6	-2.8	2.7	-0.1	-2.3	-2.1	-0.5	2.3	0.1	1.9	-0.2	2.7	2.2	-0.1	0.6
Depression (Nagel 2018)	2.9	4.3	13.9	2.6	3.7	3.0	2.5	2.5	2.2	1.2	2.8	1.5	-1.5	0.6	0.8	2.1	2.2	1.8	-1.5	2.0	1.5	-0.9	-1.6
Heel T-Score	2.9	23.4	66.9	-7.2	-3.5	-4.4	-5.3	-3.2	-1.8	6.2	-6.3	2.4	8.1	7.5	0.4	-8.2	0.8	-2.2	1.1	-5.7	-4.6	1.4	-3.1
Impedance of arm (right)	2.9	13.7	30.7	2.5	4.7	4.1	0.7	4.0	4.7	5.5	3.2	5.5	1.7	5.3	4.5	1.8	4.9	3.6	-3.4	2.5	0.3	-0.0	-3.4
Medication for hormone replacement therapy	2.8	3.1	12.0	2.3	1.5	2.0	-0.2	1.4	1.3	-0.4	2.5	0.2	-1.9	-0.4	1.1	2.1	0.6	0.7	-3.1	1.2	-0.4	-3.5	-2.5
Waist Hip Ratio (WHR)	2.7	12.0	44.4	-2.7	1.1	-0.7	-1.8	0.0	-0.1	6.4	-1.4	1.6	4.7	5.2	4.4	-4.1	2.7	-1.4	-3.0	-3.1	-4.6	-2.1	-6.7
Illnesses of mother	2.7	3.4	7.7	-2.8	-2.5	-2.2	-2.1	-2.3	-1.9	0.8	-2.6	-0.8	2.0	0.8	-1.6	-2.4	-0.8	-1.7	1.4	-2.4	-1.7	0.4	0.8
Fasting Glucose	2.6	3.1	10.4	1.2	1.1	2.2	-0.7	2.4	2.3	2.6	1.7	2.1	0.4	1.9	3.2	0.5	2.0	2.1	-0.6	2.0	1.4	0.4	-0.7
Depression (self-reported)	2.6	3.1	7.0	2.1	2.5	2.2	1.4	1.7	1.9	1.3	2.6	1.4	-0.4	1.1	1.9	1.1	1.7	1.2	-2.6	1.6	-0.3	-1.8	-2.2
Medication: Blood pressure	2.6	4.7	10.5	3.2	1.5	3.1	2.0	2.5	2.8	0.3	3.2	2.1	-2.4	0.7	0.4	2.5	1.4	2.8	-0.9	3.0	2.3	0.1	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	2.5	5.6	14.7	-3.5	-3.3	-3.0	-2.5	-2.7	-2.3	0.4	-2.8	-0.8	1.9	1.0	-1.8	-3.8	-1.4	-2.0	-0.4	-3.5	-2.8	-0.9	-1.5
High blood pressure (mother)	2.5	3.5	8.1	2.9	2.0	2.6	2.6	2.5	2.1	-0.3	2.5	1.6	-0.7	0.4	0.6	2.6	1.1	1.9	-1.6	2.6	0.6	-0.9	-1.6
Number of treatments/medications taken	2.4	4.3	11.2	2.8	2.0	3.0	1.9	2.2	2.5	-0.4	3.1	1.6	-1.8	0.3	1.5	2.1	2.0	2.4	-3.4	2.5	0.7	-0.9	-0.7
HDL Cholesterol	2.3	3.8	9.0	-2.9	-2.0	-3.0	-1.8	-2.1	-2.3	0.5	-2.8	-1.1	2.4	0.2	-0.9	-2.2	-1.5	-2.3	1.9	-2.6	-1.2	1.2	0.7
Happiness	2.3	2.8	8.1	2.5	2.0	2.4	0.7	1.6	1.9	1.2	2.8	1.1	-1.2	0.2	0.5	2.4	1.9	1.3	-1.6	1.8	0.5	-1.2	-1.9
Hair/balding pattern: Pattern 4	2.2	5.3	23.1	-3.2	-1.5	-2.2	-1.5	-1.7	-0.8	0.9	-3.7	0.6	3.3	2.3	-0.9	-3.0	-0.3	-0.3	4.8	-1.3	-0.0	3.0	2.8
Breast cancer (self-reported)	2.2	2.6	7.0	1.1	1.0	1.2	1.7	1.2	1.6	0.4	0.6	2.0	0.7	0.9	0.6	1.8	1.1	2.3	1.5	2.2	2.2	2.6	2.6
Osteoarthritis (self-reported)	2.2	2.8	7.7	2.2	0.8	2.0	2.4	0.9	1.6	-1.1	1.6	0.4	-1.7	-0.7	0.1	2.8	0.9	2.3	0.6	2.7	2.2	1.3	1.9
Neuroticism (Nagel 2018)	2.1	4.9	14.4	3.3	2.4	3.1	1.9	2.8	2.4	1.1	3.8	1.3	-0.1	0.4	2.4	2.4	1.5	2.3	-2.5	2.5	0.9	-0.9	-2.0
Worry (Nagel 2018)	2.1	4.4	11.4	2.9	2.6	2.8	0.6	2.5	2.0	1.8	3.4	0.8	-0.3	0.8	2.6	2.3	1.6	1.8	-3.0	2.2	0.1	-1.2	-2.3
Frequency of depressed mood in last 2 weeks	2.1	3.0	7.4	2.2	2.1	2.3	2.5	1.7	1.6	1.3	2.5	1.3	-2.7	-0.1	1.1	2.0	1.0	1.6	-0.4	1.7	1.9	-0.2	-0.4
Birth weight	2.1	4.5	18.6	-3.1	-1.6	-2.4	-1.7	-1.8	-2.1	1.0	-2.1	-1.2	2.9	0.8	0.9	-4.3	0.1	-2.1	-1.4	-3.2	-2.7	-0.2	-1.1
Alzheimer’s Disease (in father)	2.0	2.2	6.4	1.1	0.7	1.4	0.9	1.8	1.9	0.3	0.7	2.1	-0.3	1.0	-0.6	1.2	1.3	2.5	1.5	1.9	1.8	2.5	1.0
Diabetes (mother)	2.0	2.6	8.0	2.0	0.6	1.8	1.8	0.5	1.9	-0.3	1.6	1.4	-1.3	-0.1	0.2	2.3	0.6	2.3	1.0	2.8	2.5	1.3	1.5
Qualifications: CSEs or equivalent	2.0	2.6	7.0	2.2	-0.1	2.3	-0.3	2.0	1.9	1.0	2.3	1.4	-1.1	0.4	2.6	2.2	1.8	1.6	-1.1	1.9	1.5	-0.0	-0.2
Overall health rating	2.0	4.3	11.6	2.9	2.5	2.7	1.2	2.5	2.3	0.3	3.4	1.2	-1.4	-0.1	2.9	2.2	2.1	2.0	-2.6	2.5	1.5	-0.4	-0.6
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	6.3	-1.7	-1.6	-1.5	-1.3	-2.5	-1.5	-1.8	-2.1	-1.7	0.6	-1.2	-1.4	-1.5	-1.3	-1.1	0.5	-1.2	-0.9	0.5	0.9
Medication: Amlodipine	1.9	2.6	5.5	2.3	1.2	2.3	2.0	1.4	2.0	-0.5	2.3	1.4	-1.9	0.2	0.8	2.1	1.2	1.9	-0.5	2.2	1.8	0.1	0.2
Worry too long after embarrassment	1.9	3.3	15.4	2.3	1.5	2.4	3.9	2.0	1.9	1.4	2.9	1.6	0.3	0.8	1.1	1.7	0.9	1.9	-0.8	1.9	1.4	0.1	-0.9
Pain type(s) experienced in last month: Hip pain	1.9	2.4	6.4	2.5	0.1	2.1	1.6	1.3	1.7	-1.2	2.1	0.4	-1.5	-1.1	1.3	2.1	1.6	1.6	-0.9	2.3	2.0	-0.2	0.3
Cholesterol lowering medication	1.9	2.8	9.9	1.1	1.2	1.6	0.8	0.5	2.0	0.5	0.9	2.0	0.7	1.7	2.0	0.9	1.8	3.1	0.9	2.1	2.2	3.1	0.5
Chronic bronchitis/emphysema (mother)	1.8	2.1	4.9	-2.2	-1.1	-2.1	-1.8	-1.3	-1.7	0.5	-1.9	-1.2	0.7	-0.1	-1.6	-1.7	-1.0	-2.2	0.2	-2.2	-1.3	0.1	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.2	4.9	1.9	1.8	2.1	0.9	2.1	2.0	-0.1	1.8	1.5	0.4	0.6	1.0	2.0	1.5	2.0	-0.8	2.2	0.7	-0.0	-0.4
Number of self-reported non-cancer illnesses	1.8	3.2	7.5	2.1	1.8	2.4	1.4	2.0	2.5	-0.1	2.5	2.2	-1.5	0.8	1.3	1.8	1.3	2.7	-1.5	2.6	1.3	0.4	0.1
Type 2 Diabetes (T2D) (2012)	1.7	2.0	7.3	1.6	2.7	1.8	1.0	1.1	0.9	-0.4	1.4	0.4	-0.7	-0.2	2.1	0.9	1.9	0.7	-2.6	0.8	-0.8	-1.4	-1.2
BMI	1.7	10.0	21.5	-4.5	-2.8	-4.6	-3.3	-3.9	-4.3	-0.7	-4.0	-3.1	1.2	-1.2	-2.5	-3.8	-3.1	-3.7	2.8	-4.1	-2.3	-0.5	1.8
Ever used hormone-replacement therapy (HRT)	1.7	2.2	5.6	1.8	2.4	1.7	1.7	1.2	1.0	-1.1	1.9	0.1	-2.4	-0.8	-0.5	1.3	0.3	1.0	-2.1	1.3	0.5	-2.3	-0.6
Medication: Simvastatin	1.7	2.4	9.4	1.4	3.1	1.9	-0.7	1.6	2.0	1.3	1.7	1.8	0.5	1.7	1.2	0.1	1.5	2.3	-0.2	1.7	1.5	1.1	-0.4
Financial situation satisfaction	1.7	2.2	6.6	2.2	0.1	2.4	0.3	1.4	2.1	0.6	2.0	1.4	-1.1	-0.1	-0.3	2.6	1.3	1.7	0.5	2.0	1.8	0.2	0.3
Medication: Lisinopril	1.7	2.2	5.4	2.0	0.8	2.0	2.3	1.5	1.8	-0.3	2.1	1.2	-1.1	0.2	0.0	1.8	0.8	1.8	-0.1	2.1	2.2	0.3	0.5
Illnesses of father: High blood pressure	1.7	2.1	4.7	-1.1	-1.1	-1.5	-1.4	-0.9	-1.8	-1.0	-0.5	-1.3	-0.8	-1.5	-1.7	-1.6	-2.2	-1.8	-0.7	-1.9	-1.9	-1.9	-1.5
Irritability	1.7	2.8	7.0	2.6	2.5	2.1	0.9	2.5	1.8	-0.3	2.6	0.7	-1.8	0.1	1.6	2.4	0.5	1.4	-1.4	2.1	1.1	-0.3	-0.4
Deep venous thrombosis (DVT) (self-reported)	1.7	2.2	5.6	-1.7	-1.0	-1.9	-2.2	-1.4	-1.9	-0.4	-1.8	-1.9	0.5	-0.8	-0.5	-1.3	-0.6	-2.4	-0.2	-2.0	-2.2	-1.2	-0.8
Bipolar Disorder (2011)	1.6	1.5	7.4	0.5	1.9	1.0	-0.1	1.3	1.5	2.7	0.7	2.2	-0.3	1.6	0.5	-0.2	1.2	0.5	-1.5	0.5	0.0	-1.1	-1.0
LDL Cholesterol	1.6	2.6	12.0	-1.5	-1.5	-1.4	0.1	-1.3	-0.7	-0.2	-1.6	-0.5	1.3	0.2	-0.8	-0.6	-1.3	0.0	3.5	-0.4	1.3	3.4	3.1
Neuroticism	1.6	3.8	13.3	3.3	1.7	2.8	2.2	1.8	2.0	0.5	3.6	0.6	-1.1	-0.5	1.7	2.2	1.1	2.0	-2.1	2.6	1.1	-0.8	-0.9
Hearing difficulty/problems: Yes	1.6	2.4	11.0	1.4	1.1	0.3	2.0	-0.2	-0.3	-3.3	0.8	-1.3	-1.7	-2.4	-2.4	1.5	-0.5	0.5	1.2	1.2	1.5	-0.1	2.4
Blood clot in the leg (DVT)	1.6	2.1	5.6	-1.5	-0.8	-1.8	-2.1	-1.2	-1.9	-0.5	-1.5	-2.0	0.3	-1.1	-0.5	-1.3	-0.6	-2.4	-0.4	-1.8	-2.1	-1.4	-0.8
Triglycerides	1.5	2.4	7.0	1.8	1.0	2.0	1.5	1.0	1.8	0.3	1.7	1.2	-0.5	0.6	0.3	2.1	0.7	2.6	1.1	2.2	2.5	1.9	0.6
Allergy or Eczema	1.5	4.0	13.0	1.0	1.5	2.0	0.7	2.2	2.7	2.9	1.1	3.6	1.5	3.5	1.5	1.0	2.1	2.6	0.1	1.8	1.7	1.6	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	1.9	6.1	1.6	2.3	2.0	2.5	1.1	1.2	0.0	1.9	0.5	-1.4	-0.5	-0.2	1.9	1.1	1.5	-0.2	1.4	1.6	0.0	0.1
Mouth/teeth dental problems	1.5	2.3	7.6	-1.7	-2.8	-2.1	-0.6	-1.8	-2.2	-0.9	-1.8	-2.0	-0.1	-1.2	-0.5	-1.2	-1.3	-1.9	0.5	-2.0	-1.5	-0.9	0.3
Medication: Lansoprazole	1.5	1.7	4.9	1.2	0.4	1.1	2.2	1.0	1.5	-1.0	0.8	1.5	-0.8	0.3	-0.5	1.3	2.0	1.8	-0.2	1.6	1.4	1.6	1.0
Medication for pain relief, constipation, heartburn	1.5	2.6	9.1	-2.2	-2.0	-2.1	-3.0	-1.8	-1.5	1.0	-2.2	-0.6	1.4	0.6	0.1	-2.1	-1.8	-1.4	1.5	-1.7	-0.7	0.7	0.0
Smoking status: Current	1.5	2.3	6.9	-2.0	-0.3	-1.1	-1.0	-1.0	-0.5	2.1	-1.6	0.7	2.6	2.5	-0.9	-2.2	1.6	-1.2	0.2	-2.0	-1.6	0.1	-1.2
Depressed Affect (Nagel 2018)	1.4	3.0	8.9	2.4	2.5	2.3	2.1	2.0	1.7	0.1	3.0	0.7	-0.6	-0.1	1.9	1.3	1.4	1.4	-2.1	1.5	0.4	-1.6	-2.0
Hypothyroidism (self reported)	1.4	3.2	8.8	2.3	2.3	2.1	0.6	1.4	2.0	0.7	2.7	1.4	-1.8	0.3	3.0	2.3	1.2	2.2	-0.6	2.4	1.5	0.4	0.6
Current tobacco smoking	1.4	2.3	8.2	-1.8	-0.1	-0.8	-0.8	-0.7	-0.1	2.3	-1.5	1.1	2.6	2.9	-0.8	-1.9	2.0	-1.0	0.3	-1.8	-1.4	0.1	-1.4
Medication: Gliclazide	1.4	1.6	4.4	2.0	1.1	1.6	1.6	0.8	1.4	-0.0	2.1	0.4	-1.1	-0.4	-0.4	2.1	0.0	1.7	0.2	1.9	1.6	0.1	0.1
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	5.7	1.2	2.4	1.5	1.0	1.8	1.5	0.9	1.4	1.5	1.2	1.1	1.0	0.7	1.9	1.6	-0.9	1.4	0.6	0.3	0.1
Hair/balding pattern: Pattern 2	1.3	1.7	6.6	-1.9	-1.4	-1.6	-1.9	-0.4	-1.2	1.0	-1.9	-0.4	2.6	1.1	0.3	0.2	-0.4	-1.3	0.5	-1.6	-1.6	0.4	-0.4
Trunk fat-free mass	1.3	7.3	22.0	-1.1	-2.8	-3.0	-0.5	-3.0	-3.3	-4.7	-1.4	-4.2	-1.8	-4.7	-2.4	-0.7	-3.6	-2.3	1.7	-1.3	0.7	-0.6	3.2
Trunk predicted mass	1.3	7.3	22.5	-1.1	-2.8	-3.0	-0.5	-3.0	-3.3	-4.7	-1.4	-4.2	-1.8	-4.7	-2.3	-0.7	-3.6	-2.3	1.7	-1.2	0.8	-0.6	3.3
Length of working week for main job	1.3	1.5	4.4	-1.3	-2.0	-1.4	0.9	-1.4	-0.9	-1.0	-1.2	-0.1	1.3	0.1	-1.6	-0.7	-0.8	-0.1	2.1	-0.8	0.2	2.1	0.9
Arm fat-free mass (right)	1.3	6.8	20.3	-1.0	-2.8	-2.7	-0.6	-3.2	-2.9	-4.5	-1.2	-3.6	-1.4	-4.2	-2.3	-0.7	-3.8	-1.5	2.7	-0.9	1.5	0.7	3.6
Arm predicted mass (right)	1.3	6.6	18.9	-1.1	-2.7	-2.8	-0.8	-3.1	-3.0	-4.3	-1.2	-3.7	-1.4	-4.2	-2.3	-0.8	-3.9	-1.7	2.4	-1.1	1.2	0.3	3.2
Suffer from ‘nerves’	1.3	2.0	4.4	1.6	1.3	2.1	1.7	1.1	1.9	1.9	1.9	1.5	0.3	1.6	1.3	0.6	1.5	1.6	-0.8	1.5	0.8	0.6	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	3.8	1.3	0.6	1.2	0.4	0.7	1.9	0.5	1.2	1.9	0.0	1.0	0.6	1.5	1.7	1.6	-0.5	1.9	0.5	0.6	-0.2
Hearing aid user	1.3	1.4	4.7	0.8	1.9	0.2	1.4	0.2	-0.7	-2.2	0.9	-1.7	-1.5	-1.9	-0.5	0.6	-0.0	-0.6	-1.6	0.1	-0.9	-1.6	0.3
Arm fat-free mass (left)	1.3	6.7	17.5	-1.4	-2.5	-3.0	-0.7	-3.2	-3.2	-4.2	-1.5	-3.8	-1.5	-4.2	-2.6	-1.1	-3.6	-2.1	2.2	-1.4	0.8	-0.2	3.1
Number of operations (self-reported)	1.3	2.0	14.4	0.2	0.8	-0.1	-1.1	-0.2	-1.1	-0.5	0.5	-1.1	-1.0	-1.0	-0.2	-0.0	-0.2	-1.5	-2.0	-1.1	-2.0	-3.8	-2.6
Heart disease (siblings)	1.3	1.6	3.7	1.1	1.1	1.7	1.2	1.5	1.8	0.2	1.3	1.8	-0.5	0.9	1.2	0.7	1.3	1.9	-0.7	1.4	1.5	0.7	-0.2
Arm predicted mass (left)	1.3	6.5	17.6	-1.3	-2.4	-2.9	-0.7	-3.0	-3.0	-4.2	-1.5	-3.6	-1.8	-4.2	-2.6	-1.0	-3.6	-1.9	2.2	-1.3	0.9	-0.3	3.2
Severe depression (siblings)	1.2	1.3	4.8	1.0	-0.2	1.1	0.8	1.8	1.3	2.2	1.2	1.4	-0.5	1.5	2.1	0.5	0.5	0.5	-0.6	0.7	0.4	-0.9	-0.8
Sitting height	1.2	8.8	35.0	3.9	0.9	1.4	2.3	0.1	-0.0	-4.6	3.7	-2.5	-5.2	-5.9	-0.6	4.3	-1.6	0.7	-1.6	2.8	3.1	-1.9	2.3
Falls in the last year	1.2	1.6	5.8	-0.7	1.3	-0.7	-0.9	-0.7	-0.7	-0.1	-0.4	-0.7	0.3	0.4	-1.7	-1.1	0.6	-0.9	-2.1	-1.1	-2.3	-2.2	-2.4
Lung cancer (father)	1.2	1.4	4.9	-1.1	-0.6	-1.3	-1.1	-0.9	-1.3	-0.5	-0.7	-1.0	1.0	-0.1	0.4	-0.9	-0.9	-1.7	-0.8	-1.7	-2.0	-2.2	-1.4
Exposure to tobacco smoke outside home	1.2	1.6	4.7	1.4	0.7	0.8	0.6	0.2	0.6	-1.7	1.5	-0.2	-1.7	-1.7	-0.3	0.6	-1.1	1.4	1.3	1.6	2.0	0.6	2.2
Commuting to job workplace: Cycle	1.2	1.4	4.3	-0.9	-1.0	-1.4	0.1	-1.0	-1.6	-2.1	-0.8	-1.6	-1.7	-2.1	-1.0	-0.9	-0.9	-1.1	-0.1	-1.2	-0.4	0.5	1.1
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	6.5	0.1	0.1	-0.7	1.4	-0.9	-1.1	-2.5	-0.3	-1.7	-1.3	-2.3	-1.4	0.8	-0.7	-0.7	1.0	-0.0	-0.1	-0.0	2.1
Crohns Disease (2017)	1.1	2.5	6.2	1.4	1.1	1.8	0.2	1.6	2.0	1.4	1.4	2.1	0.6	1.1	2.3	1.7	1.7	2.5	-0.6	1.8	1.8	1.7	0.2
Major Depression (MDD)	1.1	1.4	5.6	0.1	1.3	1.0	-0.3	0.7	1.1	2.0	0.0	1.2	1.6	2.4	2.3	-0.1	1.8	0.5	0.1	0.4	-0.4	0.0	-0.8
HbA1C	1.1	1.2	3.0	1.5	0.3	1.6	1.2	1.3	1.3	0.7	0.9	1.2	0.9	0.7	1.3	1.1	0.5	1.5	0.4	1.7	1.1	0.2	-0.2
Lung FEV1/FVC ratio	1.1	5.8	19.6	-4.0	-2.0	-2.9	-3.5	-3.3	-1.5	1.1	-4.4	0.3	2.0	1.7	0.2	-3.4	0.9	-0.5	1.9	-2.1	-2.0	2.4	1.8
Average weekly spirits intake	1.1	1.4	3.3	-1.7	0.0	-1.7	-1.2	-1.4	-1.1	0.4	-1.8	-0.3	1.8	0.1	-1.1	-1.6	-0.8	-1.1	1.6	-1.2	-0.4	1.0	0.8
Supplements: Zinc	1.1	1.1	5.7	0.1	-0.2	-0.1	-0.9	0.3	-0.3	0.6	-0.1	-0.7	-1.1	-0.4	1.9	-0.2	0.8	-1.4	-1.4	-0.5	-1.9	-2.4	-1.3
Supplements: Glucosamine	1.1	1.4	6.1	0.2	0.3	-0.3	1.2	-0.1	-0.9	-1.3	0.2	-1.5	-1.7	-1.6	-0.6	-0.4	-0.6	-1.4	-1.9	-0.7	-1.2	-2.5	-1.3
Number of incorrect matches in round	1.1	1.8	8.1	-1.3	-1.3	-1.3	-2.8	-1.7	-1.6	-0.1	-1.6	-1.5	0.7	-0.2	-1.1	-0.9	-0.4	-1.6	0.1	-1.4	-1.9	-1.1	-0.3
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	6.2	1.5	1.6	1.6	1.2	1.1	1.4	0.4	1.9	0.8	-1.4	-0.2	1.5	1.4	1.0	1.5	-2.5	1.2	0.6	-0.5	-0.8
Tense / ‘highly strung’	1.1	1.8	6.1	1.3	2.5	1.0	-0.6	1.4	0.6	2.1	2.3	0.4	0.3	0.8	1.1	1.0	-0.6	0.6	-2.1	0.5	-0.5	-1.2	-2.0
Gout (self-reported)	1.1	1.5	5.3	-0.4	-1.9	-0.6	0.1	-2.3	-1.1	-2.3	-0.8	-1.6	-1.0	-1.9	-1.4	0.7	-0.2	-0.8	1.0	-0.3	-0.1	0.2	1.4
Whole body fat-free mass	1.1	6.2	17.6	-1.3	-2.6	-2.9	-0.6	-2.9	-3.1	-4.2	-1.5	-3.8	-1.3	-4.2	-2.2	-1.0	-3.3	-2.2	1.6	-1.4	0.6	-0.5	3.1
Mood swings	1.1	1.9	6.4	2.0	1.3	1.4	2.5	0.6	0.9	-0.6	2.3	0.3	-1.8	-1.2	1.7	1.7	0.2	0.8	-1.6	1.3	0.7	-0.9	-0.8
Whole body water mass	1.1	6.2	18.0	-1.4	-2.5	-3.0	-0.6	-2.9	-3.1	-4.2	-1.5	-3.8	-1.3	-4.1	-2.3	-1.0	-3.3	-2.2	1.6	-1.4	0.5	-0.5	3.0
Mother’s age at death	1.1	1.4	5.1	-1.6	-0.0	-1.4	0.8	-0.6	-1.5	-1.3	-2.1	-0.8	0.7	-0.4	-2.3	-1.2	-1.2	-1.1	0.0	-1.3	-1.1	-0.6	0.6
Basal cell carcinoma (self-reported)	1.1	1.4	3.8	2.0	0.9	1.5	0.7	1.1	0.9	-0.6	1.8	0.2	-1.7	-0.4	0.9	1.5	0.8	1.0	-0.9	1.4	0.5	-1.3	-1.1
Prostate Cancer	1.0	1.4	3.3	-1.5	-1.4	-1.6	-1.1	-0.9	-1.3	0.7	-1.5	-0.9	1.3	0.7	-1.3	-1.8	-0.5	-1.3	0.7	-1.5	-1.2	0.3	0.2
Ever had hysterectomy (womb removed)	1.0	1.2	4.5	0.8	-0.1	0.2	0.1	0.0	-0.7	-1.8	1.2	-1.6	-2.0	-2.1	-0.3	0.7	-1.3	-0.4	-1.2	-0.0	0.0	-1.5	-0.2
Diabetes (father)	1.0	1.3	3.9	1.7	0.7	1.5	2.0	0.8	1.2	-0.7	1.5	0.6	-0.9	-0.3	0.5	1.4	0.7	1.4	-0.2	1.8	1.4	0.6	0.4
Body mass index (BMI)	1.0	4.2	8.5	-2.8	-2.1	-2.9	-2.1	-2.5	-2.7	-0.9	-2.3	-1.9	0.3	-1.2	-2.2	-2.5	-2.5	-1.7	2.4	-2.3	-0.6	0.3	1.8
Pain all over the body in last month	1.0	1.1	3.9	1.2	2.0	1.2	0.7	0.8	1.1	1.0	1.6	1.2	-0.3	0.7	0.8	1.6	-0.1	0.9	-0.1	1.1	1.1	-0.1	0.5
Medication: Ramipril	1.0	1.3	3.9	0.8	-1.5	0.9	1.1	0.6	1.0	-0.9	1.2	0.9	-0.4	-0.3	1.5	0.5	-0.4	2.0	0.7	1.2	1.9	1.9	0.5
Illnesses of siblings	1.0	1.4	6.0	-1.1	-0.6	-1.6	-1.2	-1.1	-1.4	0.7	-1.2	-1.1	1.6	0.1	-0.0	-0.5	0.0	-2.4	1.0	-1.5	-1.6	-1.4	0.2
Pulse wave Arterial Stiffness index	1.0	1.1	2.7	0.9	0.4	1.2	0.9	1.0	1.5	1.6	0.4	1.6	0.3	1.1	0.4	1.0	1.6	1.2	-0.7	1.4	1.1	0.8	-0.1
Exposure to tobacco smoke at home	1.0	1.1	5.6	0.1	-0.4	-0.4	0.0	-1.2	-0.4	-2.4	0.1	-1.1	-0.3	-1.2	-0.5	-0.2	-2.0	0.3	1.6	0.5	1.0	-0.0	2.0
Pulse wave reflection index	1.0	1.3	2.8	1.1	0.7	1.4	1.7	1.0	1.5	1.4	1.1	1.6	0.7	1.4	0.6	0.6	1.1	1.6	-0.9	1.2	0.6	0.3	-0.3
Loud music exposure frequency	1.0	1.1	5.2	0.3	0.6	0.7	-0.5	0.3	0.9	2.3	0.8	1.3	1.9	2.2	0.9	-0.1	0.8	0.7	0.7	0.1	0.2	0.1	-1.1
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	4.8	-1.9	-1.4	-1.7	-1.1	-1.4	-1.4	0.4	-2.2	-0.9	1.9	0.0	-0.4	-1.0	-0.6	-1.5	1.5	-1.6	-0.8	0.7	0.5
High blood pressure (siblings)	1.0	1.4	4.7	1.4	0.4	1.6	1.2	1.4	1.3	-0.8	1.1	1.1	-2.2	-0.1	-0.6	0.9	0.6	1.8	-1.4	1.5	1.1	0.8	-0.2
Heart disease (mother)	1.0	1.2	6.8	0.8	0.6	0.6	1.1	1.0	0.7	0.3	0.7	0.8	-1.1	0.1	0.6	1.6	-1.0	1.3	1.1	1.0	2.6	1.8	0.8
Leg pain on walking	1.0	1.2	5.2	1.2	0.5	0.5	1.3	-0.6	-0.0	-1.7	1.2	-1.3	-1.7	-2.3	-1.1	1.4	0.1	0.1	-0.5	0.8	0.8	0.2	1.2
Smoking status: Previous	1.0	1.5	3.5	1.9	0.4	1.4	-0.1	0.4	1.0	-1.6	1.8	0.1	-1.8	-0.5	1.3	1.8	-0.3	1.8	-1.1	1.8	0.9	-0.4	-0.1
Mineral and other dietary supplements	1.0	1.4	5.8	-1.1	-0.1	-0.5	-2.1	-0.7	0.4	1.6	-0.7	1.5	1.8	1.3	0.3	-0.5	0.1	1.0	1.2	-0.1	1.2	2.4	0.8
Eye problems/disorders: Glaucoma	1.0	1.2	5.5	-1.5	-0.6	-1.4	-1.0	-1.3	-0.7	0.2	-1.5	0.1	0.9	-0.4	-0.7	-0.8	-0.9	0.2	1.7	-0.5	0.5	2.4	1.7
Bipolar Disorder (2018)	0.9	1.4	4.5	0.4	0.6	1.2	-0.2	1.4	1.6	2.1	0.8	1.7	0.3	1.6	1.4	-0.1	0.5	1.1	-2.0	0.7	-0.1	-0.6	-1.3
Alzheimer’s Disease (in mother)	0.9	1.1	3.3	1.4	0.3	0.7	1.4	0.8	0.3	-1.4	0.8	-1.1	-1.6	-1.1	0.8	1.0	1.8	-0.2	-1.4	0.7	-0.6	-0.9	-0.7
Breast Cancer	0.9	2.1	8.2	-1.1	0.4	-0.6	-2.1	0.1	-0.7	1.4	-0.9	-0.5	1.0	1.2	-0.3	-1.4	0.1	-1.1	-2.2	-1.6	-2.6	-2.1	-2.9
Blood White Count	0.9	6.6	18.2	2.5	3.9	3.0	0.8	3.0	3.2	3.0	2.9	3.1	-0.6	2.7	4.3	2.1	2.6	2.2	-1.6	2.5	1.3	0.1	-1.5
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	4.0	-1.2	-1.6	-1.0	-1.6	-1.0	-0.5	1.2	-1.4	0.3	0.8	0.3	-0.4	-1.1	0.2	-0.2	2.0	-0.6	-0.0	1.1	0.6
Fed-up feelings	0.9	1.7	5.1	1.8	1.4	1.3	1.5	1.3	0.7	-0.3	2.2	0.1	-0.9	-0.5	1.8	1.6	0.3	0.2	-1.8	0.8	-0.0	-2.2	-1.1
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	3.1	1.2	0.7	1.8	0.4	1.1	1.4	-0.3	1.5	0.9	-1.4	0.4	0.3	0.6	1.0	1.4	-1.3	1.0	0.8	-0.8	-0.2
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	6.5	1.2	-0.3	0.8	-0.4	-0.2	0.2	-0.7	1.2	-0.3	-2.1	-1.4	0.6	2.6	-0.6	0.9	-0.8	1.2	1.3	-0.1	0.3
Forced vital capacity (FVC)	0.9	3.4	11.7	2.1	1.4	1.3	3.0	1.7	0.5	-1.6	1.8	-0.4	-2.3	-1.5	0.8	1.5	1.5	-0.2	-3.4	1.0	-0.9	-3.2	-2.0
Pulse wave peak to peak time	0.9	1.1	2.5	-1.0	-0.4	-1.2	-0.9	-1.0	-1.5	-1.6	-0.5	-1.5	-0.0	-0.8	-0.3	-1.0	-1.6	-1.2	0.7	-1.4	-1.0	-0.7	0.2
Migraine (self-reported)	0.9	1.1	3.2	1.6	0.8	1.2	0.7	0.4	0.7	-1.3	1.5	-0.7	-0.8	-1.8	-0.4	1.3	-0.0	1.2	-0.2	1.5	1.0	-0.1	1.4
Illnesses of siblings: Diabetes	0.9	1.1	5.4	0.9	1.5	1.2	2.3	0.7	1.1	-0.0	1.3	0.6	-1.3	0.1	1.1	0.2	-0.2	1.8	-0.9	1.0	0.6	0.3	-0.6
Leg fat-free mass (right)	0.9	4.6	11.0	-1.8	-2.3	-2.8	-0.6	-2.6	-2.8	-3.3	-1.6	-3.0	-0.7	-3.3	-2.2	-1.4	-2.4	-2.0	1.2	-1.6	0.1	-0.3	2.5
Leg predicted mass (right)	0.9	4.6	10.6	-1.8	-2.2	-2.8	-0.6	-2.6	-2.8	-3.3	-1.6	-3.0	-0.7	-3.2	-2.2	-1.4	-2.3	-2.1	1.2	-1.7	-0.0	-0.4	2.5
Basal metabolic rate	0.9	4.9	12.9	-1.3	-2.2	-2.7	-0.7	-2.6	-2.8	-3.6	-1.3	-3.2	-1.1	-3.6	-1.9	-1.0	-3.0	-1.8	1.6	-1.3	0.7	-0.3	2.9
Supplements: Calcium	0.9	1.0	6.9	0.8	-0.7	0.4	-0.1	0.5	-0.2	-0.4	1.0	-0.8	-2.6	-1.8	-0.3	0.9	-1.3	0.2	0.6	0.4	1.1	0.2	0.9
Schizophrenia vs Biploar Disorder	0.8	1.0	3.3	0.9	0.2	1.0	1.1	0.2	0.9	-0.8	0.7	1.0	-0.0	0.1	0.3	0.8	0.4	1.8	1.2	1.3	1.7	1.0	1.6
Crohns Disease (2012)	0.8	1.2	3.1	1.0	0.8	1.3	-0.8	0.9	1.4	1.2	1.1	1.2	-0.5	0.8	1.8	1.1	1.6	1.4	-1.2	1.2	0.6	0.5	-0.7
Leg fat-free mass (left)	0.8	4.1	9.7	-1.5	-2.2	-2.7	-0.6	-2.4	-2.6	-3.1	-1.3	-2.8	-0.7	-3.1	-1.8	-1.2	-2.5	-1.8	1.4	-1.4	0.4	-0.2	2.7
Leg predicted mass (left)	0.8	4.2	9.7	-1.6	-2.2	-2.7	-0.6	-2.5	-2.6	-3.1	-1.4	-2.8	-0.7	-3.1	-1.9	-1.2	-2.4	-1.9	1.5	-1.5	0.3	-0.2	2.7
Had other major operations	0.8	1.0	5.9	0.8	0.7	1.0	0.4	0.6	0.3	0.1	1.4	0.7	-1.5	-0.1	0.4	0.8	-0.5	0.6	-2.4	0.2	-0.2	-1.6	-1.9
Neuroticism score	0.8	1.6	5.8	1.8	1.4	1.4	1.9	0.9	0.8	0.3	2.4	-0.1	-0.9	-0.6	1.4	1.1	0.3	0.5	-2.2	1.0	-0.3	-1.4	-1.0
Hip circumference	0.8	3.4	12.6	2.5	0.9	1.5	0.4	1.3	1.1	-1.8	2.6	0.3	-2.4	-1.8	-0.2	2.4	-0.7	2.2	0.7	2.4	3.6	0.3	2.7
Noisy workplace	0.8	0.9	2.7	1.2	0.1	0.9	1.6	0.6	0.4	-1.6	1.1	-0.3	-1.3	-1.5	-0.5	0.5	-0.5	0.9	0.1	1.0	1.4	0.2	0.9
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.4	-1.8	-0.8	-1.3	-1.1	0.1	-1.0	1.3	-1.5	0.0	1.5	1.5	-0.2	-1.7	-0.1	-1.2	1.0	-1.7	-0.9	0.0	-0.5
Glaucoma (self-reported)	0.8	0.9	5.2	-1.2	-0.2	-0.7	-1.2	-0.7	-0.1	0.6	-1.1	0.6	1.2	0.4	-0.1	-1.4	-0.5	0.8	1.1	-0.1	0.3	2.3	1.3
Neck or shoulder pain in last month	0.8	1.1	2.6	-1.5	-0.2	-1.5	1.3	-0.8	-1.0	-1.1	-1.6	0.1	1.5	0.3	-1.0	-1.4	-0.8	-0.8	0.6	-1.1	-0.5	1.2	0.9
Medication: Allopurinol	0.8	1.1	4.6	1.3	-0.0	1.0	0.3	-0.1	0.7	-0.8	0.9	0.3	-0.9	-0.6	-0.1	2.1	0.9	0.9	1.1	1.5	1.6	1.0	1.8
Medication: Omeprazole	0.8	0.9	4.3	0.3	0.5	-0.2	1.2	-0.7	-0.6	-2.1	0.0	-1.3	-1.2	-1.7	-1.1	0.9	-0.1	-0.4	0.6	0.2	-0.3	-0.5	1.7
Family relationship satisfaction	0.8	0.9	2.9	0.8	0.4	1.1	-1.0	1.2	1.2	0.5	0.9	1.2	-1.3	0.2	0.7	0.6	1.7	0.4	-1.4	0.5	-0.5	-1.2	-1.0
Ever had bowel cancer screening	0.8	0.9	3.6	1.0	1.9	1.2	1.0	0.7	1.1	-0.1	0.6	0.7	-0.6	0.0	-0.4	1.2	1.6	1.0	-0.7	1.4	0.0	-0.0	0.3
Average weekly champagne plus white wine intake	0.8	1.1	2.9	-1.4	-0.3	-1.4	-1.2	-0.9	-1.2	0.6	-1.2	-0.8	1.0	0.5	0.2	-1.7	-1.3	-1.2	0.1	-1.7	-0.9	-0.4	-0.4
Supplements: Fish oil (including cod liver oil)	0.8	1.0	4.6	1.3	0.6	0.8	2.1	0.5	-0.2	-1.5	1.1	-1.2	-1.6	-1.5	-0.8	0.5	-0.6	-0.5	-0.6	0.4	-0.2	-1.1	0.4
Risk taking	0.8	1.2	4.0	-1.7	-2.0	-1.2	-1.7	-0.7	-0.9	0.1	-1.8	-0.5	-0.4	0.3	-0.2	-1.9	-0.6	-0.8	-0.1	-1.3	-0.9	-0.0	-0.3
Ever depressed for a whole week	0.8	1.0	4.0	0.2	0.5	0.3	1.4	-0.6	0.6	0.2	0.3	0.8	0.8	0.7	-0.3	0.8	0.0	1.0	1.9	0.9	1.4	2.0	1.8
Bipolar Disorder or Schizophrenia	0.7	1.7	8.4	0.9	0.6	1.4	-0.7	1.0	1.3	1.8	1.4	1.4	-1.3	0.5	1.6	0.1	0.6	1.1	-2.9	0.8	-0.2	-1.5	-1.6
Ulcerative Colitis (UC)	0.7	1.3	5.7	1.2	0.1	0.6	1.4	0.5	0.2	-2.0	1.0	-0.7	-1.7	-1.8	0.0	1.2	0.9	-0.2	-2.4	0.8	-0.3	-1.2	0.2
Ulcerative Colitis	0.7	1.0	5.1	0.3	-0.3	-0.4	0.6	-0.2	-0.7	-2.3	0.2	-1.0	-1.4	-1.8	-0.5	0.1	0.1	-0.7	-2.1	0.0	-1.1	-1.0	0.6
Blood Red Count	0.7	6.4	13.6	2.9	2.3	3.4	0.5	2.6	3.3	1.6	2.7	3.7	0.0	2.7	3.3	2.5	3.1	3.5	-1.4	2.8	1.9	0.6	-1.4
Lung FVC	0.7	3.8	13.4	2.0	2.4	1.4	2.6	1.8	0.4	-1.4	1.4	-0.9	-2.5	-1.9	-0.4	1.8	2.2	-0.3	-3.1	0.8	-1.2	-3.7	-2.3
Vitamin and mineral supplements	0.7	0.9	3.1	-1.3	0.0	-1.3	-0.1	-1.8	-0.8	-0.4	-1.5	-0.6	1.5	0.2	-0.5	-0.2	0.1	-0.1	1.4	-0.6	-0.2	1.5	0.9
Medication: Levothyroxine sodium	0.7	1.3	4.9	1.4	1.1	1.1	-0.4	0.2	0.9	-0.1	1.8	0.1	-2.2	-0.8	2.1	1.5	0.6	0.9	-1.0	1.2	0.5	-0.8	0.0
Chronic bronchitis/emphysema (father)	0.7	0.9	2.8	-0.8	-0.7	-0.5	-0.7	-0.4	-0.7	0.2	-0.3	-0.4	-0.7	-0.5	0.5	-1.5	-0.8	-0.9	-1.5	-1.3	-1.3	-1.7	-1.1
Time employed in main current job	0.7	0.8	3.1	-0.1	0.8	0.1	-1.0	0.7	0.5	1.4	-0.7	0.6	0.2	1.3	0.6	0.0	1.8	0.1	-1.2	0.3	-1.4	-0.4	-1.0
Hair/balding pattern: Pattern 3	0.7	1.0	5.8	-0.2	-1.1	-0.4	-1.0	-1.5	-0.6	-1.0	0.1	-1.0	0.5	-0.9	-2.4	-0.8	-2.3	0.1	0.7	-0.3	0.3	0.1	-0.4
Mouth/teeth dental problems: Bleeding gums	0.7	1.0	2.1	-0.4	0.6	-0.9	-1.1	-0.7	-1.4	-1.0	-0.3	-1.3	-0.1	-1.4	-1.1	-1.0	-1.0	-1.4	-0.6	-0.9	-0.8	-1.4	-0.4
Medication: Paracetamol	0.7	1.1	3.4	1.3	1.2	1.3	1.8	0.3	1.0	-0.8	1.6	0.6	-0.1	0.2	-0.2	1.6	1.4	1.2	-1.1	1.1	0.5	-0.3	-0.2
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	4.6	1.1	1.4	1.1	-0.6	0.6	1.2	0.7	1.5	0.9	-1.8	0.1	2.1	1.3	0.8	1.3	-0.5	1.4	0.8	0.5	0.6
Forced vital capacity (FVC), Best measure	0.7	2.4	9.0	1.9	1.5	1.3	2.0	1.8	1.1	-0.0	1.7	0.6	-1.4	-0.2	0.8	1.3	2.1	0.1	-3.0	1.0	-0.6	-2.4	-2.1
Eye problems/disorders: None of the above	0.7	0.8	2.2	1.3	0.7	1.5	0.6	1.4	1.2	-0.2	1.3	1.0	-0.9	0.3	-0.6	1.3	0.5	1.0	-0.4	1.2	0.4	-0.3	0.1
Chest pain or discomfort	0.7	1.0	3.7	-0.1	-0.5	-0.8	0.1	-1.4	-1.2	-1.8	-0.2	-1.6	0.8	-1.9	-1.2	-0.6	-1.1	-0.3	0.9	-0.2	0.4	0.4	0.8
Age at last live birth	0.7	1.1	5.6	-1.1	0.3	-0.8	-1.3	-0.0	-0.4	0.8	-1.2	0.1	2.4	1.0	0.3	-1.5	-0.2	-0.9	-1.0	-1.0	-1.4	-1.1	-0.8
Long-standing illness, disability or infirmity	0.7	1.1	3.0	1.4	0.7	1.2	0.7	0.6	1.1	-0.3	1.3	0.4	0.1	0.5	0.1	1.7	1.0	1.7	0.3	1.7	1.6	1.1	0.7
Eye problems/disorders: Cataract	0.7	0.8	6.5	0.8	0.6	0.7	-0.0	0.3	0.4	-0.0	0.9	0.1	0.5	0.1	2.5	0.1	1.2	0.3	-1.7	0.4	0.2	-1.1	-1.0
Unable to work because of sickness or disability	0.7	0.9	4.1	1.3	1.2	1.4	0.1	0.9	0.9	0.1	2.0	-0.3	-1.3	-0.5	1.0	-0.1	0.5	1.0	-1.2	0.8	0.7	-0.2	-0.9
Pain experienced in last month	0.7	1.2	10.9	-0.2	0.8	0.3	-1.4	0.4	0.4	3.3	-0.1	1.0	1.3	1.8	1.2	-0.6	0.6	0.1	0.5	-0.3	-0.1	-0.0	-1.6
Alzheimer’s Disease (including proxy)	0.6	0.8	1.8	1.3	-0.2	1.0	1.2	1.1	1.1	-0.7	0.7	0.4	-1.3	0.0	0.6	1.1	1.4	1.0	-0.8	1.1	0.4	0.6	-0.0
Irritable Bowel Disease (IBD)	0.6	1.4	3.8	1.5	0.6	1.3	1.2	1.2	1.2	-0.6	1.4	0.6	-0.8	-0.6	1.4	1.7	1.5	1.2	-1.9	1.4	0.7	0.0	0.1
Age at First Birth	0.6	0.9	3.0	-1.5	-1.0	-0.9	-0.3	-0.8	-0.2	1.3	-1.5	0.6	0.5	1.5	-0.5	-1.7	-0.4	-0.6	0.4	-1.1	-1.0	0.1	-0.5
Neuroticism (2016)	0.6	0.8	2.8	-0.4	-1.4	-0.5	1.7	-1.2	-0.9	-0.9	0.2	-1.6	0.4	-1.2	-0.3	-1.0	-1.0	-0.5	-0.3	-0.7	-0.1	0.4	-0.4
Schizophrenia (2014)	0.6	1.2	5.4	1.1	0.7	1.4	0.3	0.6	1.0	0.2	1.6	1.1	-2.3	-0.6	0.9	0.5	-0.2	1.6	-2.0	1.2	0.6	-0.8	-0.1
Average weekly fortified wine intake	0.6	0.7	3.3	-0.7	-1.3	-0.8	0.8	-1.3	-0.5	-0.2	-0.8	-0.5	-0.3	-0.4	-1.8	-0.4	-0.6	-0.9	1.2	-0.5	-0.1	0.6	0.5
Maternal smoking around birth	0.6	0.9	3.6	-1.3	-0.5	-0.8	-1.6	0.1	0.2	1.5	-1.1	1.3	1.2	1.9	0.4	-1.1	0.1	-0.4	0.2	-0.9	-0.3	0.2	-0.6
Hayfever, allergic rhinitis or eczema	0.6	1.4	4.7	0.0	0.3	0.6	0.4	0.9	1.4	1.2	-0.1	2.2	1.5	2.1	0.5	0.6	0.9	1.4	1.0	0.9	1.5	1.8	0.6
Multivitamins +/- minerals	0.6	0.8	2.9	1.3	0.3	1.1	0.4	1.2	0.2	-0.1	1.5	-0.4	-1.7	-0.8	0.4	0.8	-0.3	0.1	-1.0	0.5	-0.0	-1.7	-1.1
Nervous feelings	0.6	1.2	4.1	1.7	2.0	1.4	1.3	0.9	0.9	0.0	1.7	0.0	0.4	-0.0	0.7	1.3	0.9	1.0	-1.1	1.5	-0.2	-0.0	-0.6
Allergy	0.6	1.3	6.0	1.5	0.8	1.0	1.0	0.4	0.5	-0.9	1.5	-0.6	-2.5	-1.3	-0.0	0.7	0.2	0.1	-1.8	0.6	-0.6	-2.1	-0.9
Fluid intelligence score	0.6	1.3	3.7	-1.9	-0.2	-1.3	-0.4	-0.6	-0.4	1.6	-1.9	0.9	1.5	1.6	-0.1	-1.3	-0.4	-0.8	1.6	-1.2	0.3	1.4	0.6
Worrier / anxious feelings	0.6	1.1	3.8	1.4	1.1	1.4	0.8	1.4	0.8	1.2	1.9	-0.0	-0.5	-0.0	1.0	0.9	0.5	0.4	-1.8	0.8	0.1	-1.3	-1.1
Asthma	0.6	1.1	3.0	-1.0	-1.6	-1.0	-1.0	-0.9	-1.4	-0.5	-0.7	-1.3	1.7	-0.5	0.0	-0.7	-1.2	-0.8	1.6	-1.1	0.1	1.5	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	5.6	0.7	1.4	0.4	0.7	-0.1	0.1	-0.5	1.4	-0.4	-0.5	-0.5	0.4	0.4	0.3	0.1	-2.4	0.1	-1.2	-1.4	-1.2
Peak expiratory flow (PEF)	0.6	1.3	6.8	1.1	1.1	0.4	2.6	0.6	0.4	-2.1	0.7	0.1	-1.5	-1.5	0.3	1.0	1.4	0.5	-1.2	1.2	0.1	-0.7	0.0
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.3	0.7	1.2	1.0	-0.8	0.6	1.2	1.5	0.9	1.2	-0.0	0.8	0.9	0.3	0.5	0.8	0.1	0.7	0.6	0.7	-0.7
Number of full brothers	0.6	0.8	4.5	0.8	1.4	0.9	2.1	1.0	0.9	0.6	0.9	0.9	-0.5	0.4	0.0	-0.4	1.2	0.7	-0.8	0.7	0.1	0.2	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.8	-0.2	0.8	0.0	-1.2	0.2	0.2	1.6	0.8	-0.2	0.4	0.8	0.7	-1.5	-0.1	-0.1	-1.0	-0.6	-1.3	-1.3	-1.7
Age at first live birth	0.6	1.0	4.0	-1.5	-0.7	-1.3	-0.8	-0.1	-0.8	0.6	-1.7	-0.1	2.0	0.8	0.4	-1.7	-0.7	-0.9	0.6	-1.3	-0.7	0.4	0.2
Had major operations	0.6	0.7	4.3	0.6	-0.2	0.1	0.6	0.0	-0.6	-1.7	0.2	-1.2	0.1	-1.3	-0.0	0.4	0.5	-0.8	-0.9	-0.0	-0.9	-2.1	-0.1
Commuting to job workplace: Car/motor vehicle	0.6	0.7	3.3	-0.4	0.4	-0.1	0.1	0.4	0.4	1.3	-0.2	0.9	1.7	1.8	0.1	-0.3	1.4	-0.3	0.9	-0.5	0.3	0.6	-0.4
Knee pain experienced in last month	0.6	0.9	3.4	1.3	-0.1	0.7	0.5	0.4	0.4	-1.7	1.3	-0.7	-1.8	-1.3	0.0	1.2	0.2	0.2	-1.1	0.9	-0.0	-1.0	0.6
Loneliness, isolation	0.6	0.8	4.5	0.9	1.1	1.0	2.1	0.0	0.4	-0.2	1.6	0.2	-0.5	-0.2	-0.6	0.2	0.6	0.7	-1.4	0.3	-0.1	-0.9	-0.9
Back pain experienced in last month	0.6	0.8	3.6	-0.1	-0.8	-0.4	1.4	-0.0	-0.6	-1.9	0.1	-1.2	-1.0	-1.7	-0.4	-0.5	-0.4	-0.7	-1.2	-0.4	-0.4	-1.0	-0.1
Asthma (self-reported)	0.6	1.2	3.6	-1.1	-1.5	-1.0	-1.0	-0.9	-1.3	-0.5	-0.8	-1.0	1.7	-0.4	-0.1	-0.8	-1.3	-0.6	1.9	-1.0	0.2	1.7	0.6
Osteoporosis (self-reported)	0.6	0.8	1.9	0.8	-0.1	1.1	0.2	1.3	1.3	0.2	0.7	1.3	-1.1	0.0	0.2	0.8	0.0	1.4	0.6	1.3	1.0	0.8	0.9
Miserableness	0.6	1.1	3.7	1.2	0.4	0.7	1.9	0.5	-0.0	-1.6	1.5	-0.8	-1.2	-1.9	0.4	0.5	0.0	-0.1	-1.6	0.3	-0.5	-1.3	-0.4
Medication: Atorvastatin	0.6	0.7	3.1	-1.0	-1.1	-0.9	0.1	-1.8	-0.6	-0.7	-1.1	-0.4	0.1	-0.4	-0.6	-0.9	-0.3	-0.3	1.3	-0.6	0.1	0.9	1.0
Diastolic blood pressure, automated reading	0.6	1.8	5.2	1.8	0.2	1.1	0.2	-0.1	0.6	-1.1	1.6	-0.2	-1.9	-1.9	0.3	2.2	-0.7	1.0	0.2	1.9	2.3	1.0	1.9
Alcohol drinker status: Previous	0.6	0.7	1.8	-1.2	-0.2	-1.1	-1.1	-1.1	-1.0	0.2	-1.1	-0.8	0.2	-0.4	-0.0	-1.3	0.2	-1.3	0.7	-1.2	-0.4	0.5	0.5
Intelligence (Savage-Jansen 2018)	0.5	1.4	3.9	-1.5	-1.9	-1.2	-0.4	-0.7	-0.3	1.1	-1.7	1.2	0.5	1.2	0.4	-1.2	-0.9	0.0	2.0	-0.5	1.1	1.9	1.0
Ovarian Cancer	0.5	0.6	2.9	-0.1	-0.5	-0.5	-0.7	-0.7	-0.6	-0.3	-0.5	-0.7	-0.8	-0.8	0.0	-0.6	-0.3	-0.9	-1.2	-0.2	-1.4	-1.0	-1.7
Primary Biliary Cirrhosis	0.5	0.8	2.2	0.7	0.2	0.5	1.4	-0.5	0.3	-1.2	0.8	0.0	0.2	-1.0	-0.3	0.2	0.3	1.0	1.1	1.1	1.0	1.4	1.5
Angina	0.5	0.6	3.4	1.1	1.8	0.7	0.7	0.9	0.5	-0.5	0.9	0.2	-0.6	-0.1	-0.6	0.2	-0.1	0.7	0.8	0.9	1.0	0.5	0.7
Pack years adult smoking proportion	0.5	0.8	6.5	-0.9	-0.9	-0.1	-2.5	-0.8	-0.1	1.2	-0.4	0.6	1.1	1.1	0.2	-0.7	0.0	0.0	1.0	-0.7	0.6	1.1	0.4
Stomach or abdominal pain in last month	0.5	0.7	2.3	-0.8	-1.5	-0.9	-1.1	-0.8	-0.8	-1.2	-1.2	-0.7	0.3	-0.3	-0.6	-0.3	-0.3	-0.9	-0.2	-0.7	-0.7	0.3	0.8
Alcohol usually taken with meals	0.5	0.8	4.0	-0.2	1.6	0.3	1.5	1.2	0.1	0.5	-0.1	0.0	-0.7	0.3	1.0	-0.2	0.3	-0.5	-2.0	-0.5	-1.1	-1.3	-0.4
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	3.6	0.1	-0.8	0.2	0.2	-0.1	0.6	0.5	-0.0	0.7	1.2	0.7	0.4	1.3	-0.1	0.9	0.9	0.7	1.2	1.9	0.7
Weight	0.5	2.4	5.5	-1.5	-1.4	-2.2	-1.6	-2.0	-2.0	-1.5	-0.9	-1.8	-0.2	-1.8	-1.4	-1.3	-2.3	-1.0	1.7	-1.2	0.5	0.0	2.1
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	6.6	0.5	0.4	-0.2	2.2	0.3	-0.5	-2.0	0.1	-0.9	-1.7	-1.6	0.2	0.0	1.0	-0.8	-2.6	-0.1	-1.7	-2.4	-1.2
Number of children fathered	0.5	0.6	4.4	0.1	0.6	0.4	1.3	0.9	0.4	0.3	-0.3	0.0	0.5	0.7	1.2	0.3	2.1	-0.1	-0.7	0.5	-0.5	0.0	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	2.0	0.6	0.5	0.7	-0.2	0.7	1.0	0.6	0.1	0.8	1.4	1.4	0.6	0.4	0.7	1.0	0.7	0.9	-0.1	0.0	-0.1
Shortness of breath walking on level ground	0.5	0.6	1.9	0.8	1.4	1.1	0.7	1.1	0.6	-0.7	1.2	-0.6	0.7	-0.5	-0.7	-0.4	0.2	0.4	-1.1	0.4	-0.2	-0.8	-0.5
Qualifications: College or University degree	0.5	1.5	4.2	-1.9	-1.8	-1.6	0.2	-0.6	-1.0	0.7	-2.0	-0.1	0.4	1.1	-0.7	-1.8	-1.4	-1.3	1.4	-1.5	-0.7	0.5	0.1
Emphysema/chronic bronchitis	0.5	0.6	3.0	0.8	0.4	0.8	0.3	-0.6	0.7	-0.6	0.8	0.4	-0.5	-0.4	-0.4	-0.1	-0.2	1.4	0.5	1.2	1.7	1.0	0.4
Angina (self-reported)	0.5	0.6	3.8	1.2	1.9	0.8	0.6	0.9	0.5	-0.3	1.0	0.2	-0.7	-0.1	-0.3	0.3	-0.0	0.8	0.7	1.0	1.0	0.3	0.6
Medication: Ibuprofen	0.5	0.6	2.2	0.6	-0.4	1.0	1.3	0.7	1.0	-0.3	0.5	1.3	0.1	0.2	0.1	0.6	1.5	1.1	-0.9	0.7	0.4	0.5	-0.2
Mean time to correctly identify matches	0.5	0.9	3.2	0.7	1.4	0.8	0.9	0.4	0.8	1.6	0.5	0.3	-0.2	0.7	0.2	1.8	1.1	0.4	1.0	0.7	1.1	1.2	0.8
Comparative height size at age 10	0.5	2.8	5.1	2.0	1.8	2.0	2.1	1.6	1.8	-0.1	2.1	1.2	-0.9	0.1	1.9	1.5	1.9	2.0	-2.3	1.9	1.9	-0.7	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.5	-0.0	-0.6	-0.8	0.0	0.1	-1.0	-0.5	-0.1	-1.2	0.2	-1.0	0.5	0.5	-0.1	-1.6	-0.8	-0.8	-1.0	-1.3	-0.9
Supplements: Vitamin C	0.5	0.6	2.4	-0.1	-0.4	0.4	-1.2	0.9	0.8	1.0	0.1	1.2	-0.0	1.3	1.2	-1.6	0.1	-0.0	0.5	-0.1	0.5	0.2	0.3
Average weekly red wine intake	0.5	0.7	2.4	-1.5	0.2	-0.9	0.1	0.2	-0.4	1.2	-1.2	0.5	1.2	1.1	-0.2	-1.6	-0.0	-0.5	0.4	-1.2	-0.7	0.9	0.0
Friendships satisfaction	0.5	0.6	2.6	0.8	1.6	0.8	0.7	1.0	0.8	1.0	1.0	0.8	0.2	0.5	0.2	0.7	0.9	0.7	-0.6	0.8	0.1	-0.5	-0.3
Qualifications: nursing, teaching	0.5	0.8	2.6	-1.0	-0.7	-0.7	-0.4	0.2	-0.3	0.5	-1.6	0.2	0.3	1.4	-0.0	-1.6	1.0	-1.0	-1.1	-0.8	-1.5	-0.4	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	4.9	0.4	-0.1	-0.0	0.8	0.5	-0.2	-1.1	0.1	-0.7	-2.2	-1.6	-0.7	0.8	0.3	-0.5	-1.3	0.1	-1.1	-1.9	-1.2
Guilty feelings	0.5	0.8	4.3	-0.5	-0.2	-0.6	2.1	-0.6	-0.8	0.1	-0.0	-0.8	0.9	-0.2	-0.0	-1.0	-1.2	-0.6	-1.0	-0.6	-1.4	-1.3	-0.6
Alcohol drinker status: Never	0.5	0.6	3.8	0.2	0.7	0.5	-1.9	0.6	0.7	1.5	0.4	1.2	-0.6	0.4	1.1	0.4	0.1	0.6	0.3	0.3	0.7	0.5	-0.3
Age started oral contraceptive pill	0.5	0.6	2.6	-0.6	-0.5	-0.2	-0.1	-0.5	0.4	0.4	-0.9	1.0	0.5	1.5	-0.4	-0.7	-0.2	0.7	1.5	-0.0	0.6	1.6	0.7
Myopia	0.5	0.8	3.1	0.8	-0.4	0.9	-0.4	0.5	0.9	1.0	1.2	0.6	0.2	0.9	0.8	-0.6	0.3	0.7	-1.8	0.5	-0.5	-0.8	-1.6
Pack years of smoking	0.5	0.7	5.6	-0.5	-0.5	0.2	-2.4	-0.7	0.1	0.8	-0.2	0.5	0.9	0.9	-0.1	-0.4	-0.1	0.4	1.1	-0.2	1.0	1.2	0.6
Schizophrenia (2018)	0.4	0.9	4.3	0.8	0.3	0.8	-0.2	0.2	0.4	0.6	1.1	0.3	-2.0	-0.7	0.9	0.2	0.4	0.5	-2.1	0.5	-0.3	-1.4	-1.1
Verbal and Numeric Reasoning (VNR)	0.4	0.9	6.7	-0.4	-0.1	-0.0	-0.8	0.8	0.5	2.6	-0.5	1.6	0.1	1.6	1.7	-0.1	0.4	0.1	-0.1	-0.1	0.8	0.5	-0.6
Coronary Artery Disease (CAD)	0.4	0.5	3.7	0.7	0.6	0.4	0.1	0.4	0.3	-1.9	0.8	-0.6	-0.6	-1.2	-0.6	0.5	-0.0	0.2	-0.0	0.3	0.6	0.4	1.0
Blood Platelet Count	0.4	4.8	11.4	2.5	1.8	2.3	1.2	1.6	2.5	2.6	2.9	2.6	-1.4	0.6	2.9	2.3	0.5	2.5	1.4	2.8	3.4	2.1	0.4
Type 2 Diabetes (T2D) (2018)	0.4	0.8	3.6	-0.0	-1.9	-0.5	-0.5	-1.2	-0.4	-0.4	-0.2	-0.7	-0.1	-0.8	-0.6	0.9	-0.6	-0.0	1.6	0.3	1.2	0.8	1.8
Medication: Metformin	0.4	0.6	1.6	1.0	-0.6	0.6	0.9	-0.5	0.5	0.0	0.7	-0.2	-0.7	-0.3	0.1	1.3	0.7	0.8	1.1	1.2	1.2	0.5	1.1
Trunk fat percentage	0.4	1.7	7.6	-0.2	1.5	0.6	-1.3	0.6	1.2	2.8	0.8	2.1	1.4	2.3	1.4	-0.5	0.9	1.7	-0.1	0.3	0.5	0.5	-0.6
Townsend deprivation index at recruitment	0.4	0.6	2.5	-0.3	-0.8	-0.3	1.0	-1.1	-0.5	-0.9	-0.2	-0.6	0.2	-0.5	-0.6	-0.6	-0.1	0.2	1.3	-0.2	0.4	1.2	1.6
Relative age voice broke	0.4	0.7	2.7	1.0	1.1	0.9	-0.4	1.3	1.0	0.3	1.2	0.7	-1.6	0.1	-0.7	0.3	-0.4	0.7	-0.2	0.8	0.5	-0.5	-0.6
Taking other prescription medications	0.4	0.5	1.6	0.9	0.7	0.8	1.0	0.3	0.7	-1.1	1.0	0.1	-0.6	-0.4	0.2	0.7	0.3	1.1	-0.3	1.3	0.3	0.2	1.1
Past tobacco smoking	0.4	0.6	2.7	-1.0	-0.1	-0.8	0.2	0.5	-0.5	1.6	-1.1	0.0	1.1	0.1	-0.5	-0.8	-0.1	-1.3	1.3	-0.9	-0.1	0.6	0.7
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	3.5	0.5	1.9	0.5	0.5	-0.9	0.3	0.3	0.9	0.1	-0.3	-0.2	-0.2	0.5	0.8	0.4	0.6	0.4	0.6	0.9	0.6
Diabetes (self-reported)	0.4	0.6	2.2	0.4	-0.6	-0.2	-0.7	-0.7	-0.0	-0.6	0.1	-1.0	-0.2	-1.0	-0.8	1.3	0.2	0.1	1.2	0.7	1.1	0.5	1.5
Number of live births	0.4	0.6	1.5	0.4	1.1	0.8	0.6	0.9	0.8	1.2	0.6	1.2	0.5	1.1	-0.2	0.5	0.7	0.5	-0.9	0.3	-0.2	-0.4	-1.0
Pulse rate	0.4	0.7	3.4	-0.2	0.2	0.2	-0.9	0.3	0.2	0.8	-0.2	-0.2	-0.7	0.2	1.6	-0.1	1.1	-1.0	-1.1	-0.7	-0.9	-1.2	-1.8
Qualifications: A levels/AS levels or equivalent	0.4	0.9	6.8	-0.8	1.2	-0.0	0.9	1.0	0.5	1.4	-0.7	1.2	1.1	2.6	0.1	-1.2	0.8	0.2	0.0	-0.3	-0.1	0.4	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	6.0	0.5	0.9	0.2	1.5	1.0	0.4	-0.3	0.2	0.6	-0.8	0.1	0.7	0.2	2.1	-0.2	-2.5	0.2	-1.4	-1.7	-1.6
Arm fat mass (right)	0.4	1.5	4.1	-2.0	-0.8	-1.9	-1.8	-1.5	-1.5	0.4	-1.2	-0.7	0.6	-0.1	-0.8	-1.9	-1.3	-0.6	1.4	-1.5	-0.2	0.2	1.1
Headache pain in last month	0.4	0.8	2.2	-0.9	-0.3	-0.9	0.2	-0.8	-0.9	-0.8	-0.7	-1.0	-0.3	-0.5	-0.5	-1.1	0.3	-1.5	-1.4	-1.1	-1.5	-0.9	-0.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	2.4	-0.6	-0.3	-0.5	-1.6	-1.0	-0.3	0.1	-1.1	0.2	-0.2	0.1	-1.0	0.5	-0.3	-0.5	1.4	-0.2	0.1	0.6	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.6	0.5	0.8	0.2	1.0	0.9	-0.1	-1.2	0.7	-0.7	-0.2	-0.8	-0.2	0.7	-0.2	-0.3	-0.4	0.1	-0.1	-1.2	0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.2	1.0	0.7	0.8	1.1	1.5	0.4	0.1	1.0	-0.8	-0.1	-0.1	-0.2	0.4	0.5	-0.1	-0.7	0.2	-0.4	-0.9	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.0	0.3	-0.0	0.4	-0.4	0.6	1.1	0.3	-0.1	1.1	-1.2	0.2	0.7	0.9	0.6	0.7	1.0	1.0	0.8	1.4	0.5
Commuting to job workplace: Public transport	0.4	0.4	2.0	-0.5	-0.8	-0.8	0.2	-0.5	-0.8	-0.5	-0.5	-0.9	0.1	-1.0	-0.5	-0.3	-1.4	-0.6	0.4	-0.6	-0.1	0.2	0.6
Average weekly beer plus cider intake	0.4	0.6	1.7	1.0	-0.4	0.3	-0.9	0.3	-0.1	-1.0	1.2	-1.3	-0.7	-1.3	1.3	0.3	0.4	-0.4	-0.4	0.4	-0.1	-0.4	-0.5
Reaction Time	0.3	0.6	3.1	-0.2	0.3	-0.3	0.1	-0.7	-0.1	1.3	-0.2	-0.2	0.3	0.2	0.2	1.0	0.1	-0.4	1.8	-0.1	0.9	1.6	1.1
Body Mass Index (BMI) (2010)	0.3	0.4	2.4	0.8	0.9	0.5	0.5	0.6	0.4	-0.6	0.8	-0.1	-0.1	-0.2	-0.9	1.5	0.0	0.4	-0.3	0.8	-0.0	-1.0	-0.1
Lupus	0.3	0.5	1.8	0.5	0.5	0.7	0.8	0.2	0.9	1.2	0.3	0.9	0.1	1.1	0.4	-0.5	1.3	0.8	-0.5	0.6	-0.2	-0.3	-0.5
Blood Eosinophil Count	0.3	2.5	13.1	-0.2	1.5	0.7	-0.7	1.3	1.6	3.6	0.6	2.5	1.4	3.4	2.3	0.4	1.0	1.2	0.6	0.6	0.2	0.9	-0.4
Height	0.3	6.3	15.4	3.6	2.8	2.5	2.1	1.8	2.6	-1.8	3.2	1.1	-1.7	-0.7	2.8	3.9	1.8	2.8	-3.2	3.7	2.6	-0.8	0.9
Smoking Status	0.3	0.7	2.2	-1.0	-0.7	-0.7	-1.2	-1.2	-0.3	0.2	-0.9	0.2	1.4	1.5	-0.8	-1.2	0.5	-0.3	0.5	-0.8	-0.5	0.5	-0.4
Tanning	0.3	3.5	10.0	-1.9	-1.5	-2.6	-2.6	-2.1	-2.3	0.4	-1.8	-1.7	1.2	-1.4	-1.3	-1.6	-3.2	-1.6	2.5	-1.7	-0.2	1.3	1.8
Hand grip strength (left)	0.3	0.8	3.3	1.3	-0.4	0.7	1.0	1.0	0.4	-0.4	1.1	-0.1	-0.5	-0.8	1.3	1.3	-0.2	0.1	0.7	1.0	1.8	-0.0	0.5
Medication: Co-codamol	0.3	0.3	3.4	0.0	0.4	0.2	1.8	0.1	0.3	0.6	-0.2	0.2	-0.4	0.5	0.4	0.8	0.8	0.2	0.0	0.2	0.1	0.6	0.3
Hand grip strength (right)	0.3	0.9	2.9	0.1	-0.8	-0.8	0.6	-0.2	-1.1	-1.3	-0.1	-1.5	-1.7	-1.7	0.5	0.6	-1.0	-1.4	0.5	-0.3	0.3	-0.7	0.6
Age when periods started (menarche)	0.3	0.8	3.5	-0.2	-0.2	-0.4	0.5	-0.2	-0.0	0.3	-0.1	0.4	1.8	0.5	0.5	0.8	-0.8	-0.2	1.8	0.1	1.1	1.9	1.2
Arm fat percentage (right)	0.3	1.4	4.2	-2.0	0.0	-1.3	-2.0	-0.5	-0.7	2.0	-1.0	0.6	1.3	1.5	0.2	-2.0	-0.1	-0.3	0.4	-1.5	-0.9	-0.1	-0.2
Alcohol intake versus 10 years previously	0.3	0.5	3.1	-0.0	-0.5	0.0	-0.4	-0.3	0.4	-0.7	-0.3	0.4	0.5	-0.2	-0.4	-0.1	-0.1	1.1	1.0	0.6	0.8	1.3	1.8
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.2	0.4	0.1	0.7	1.1	0.7	0.5	-0.5	0.3	0.4	0.0	-0.3	0.1	0.3	1.2	0.3	-1.5	0.2	-0.4	-0.7	-0.6
Breastfed as a baby	0.3	0.4	2.8	0.5	1.7	0.3	0.6	0.4	0.4	-0.3	0.4	0.5	0.1	0.4	-0.2	0.6	0.9	0.0	-1.1	0.3	-0.4	-1.0	-0.3
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.8	-0.5	-0.2	-0.1	-0.4	-0.9	-0.1	-0.2	-0.5	-0.1	1.1	-0.2	-0.8	-0.5	0.2	0.3	0.8	-0.1	0.7	1.7	0.4
Body fat percentage	0.3	1.1	5.2	-0.6	0.9	-0.1	-1.7	0.1	0.5	2.3	0.2	1.6	1.2	1.9	1.1	-0.9	0.2	1.2	0.5	-0.1	0.4	0.6	-0.2
Wheeze or whistling in the chest in last year	0.3	0.5	1.7	-1.0	0.1	-0.7	-1.3	-0.4	-0.7	0.0	-0.7	-0.4	0.8	0.5	-0.7	-1.1	-0.6	-0.6	0.0	-0.8	-1.0	-0.1	-0.3
Medication: Seretide 50 evohaler	0.3	0.4	2.6	-0.2	-0.3	-0.1	-1.6	-1.3	-0.6	0.6	-0.2	-0.3	0.8	0.1	0.3	-0.7	-0.5	-0.2	0.3	-0.3	0.4	0.6	-0.1
Leg fat mass (right)	0.3	1.1	4.3	-1.2	-0.7	-1.4	-2.1	-1.4	-1.1	-0.1	-0.8	-0.6	0.2	-0.4	-0.3	-1.0	-1.4	-0.1	1.7	-0.7	0.5	0.6	1.4
Medication: Aspirin	0.3	0.3	1.6	0.4	-0.3	0.3	0.4	0.9	0.2	0.7	0.2	0.1	-0.4	0.1	0.4	-0.2	0.2	0.3	1.3	0.4	1.3	0.6	0.8
Illnesses of father: Heart disease	0.3	0.4	1.5	-0.4	0.6	-0.2	-0.8	-0.4	0.3	-0.7	-0.7	0.2	0.8	1.2	-0.7	-0.3	0.6	0.6	-0.1	-0.1	-0.7	0.8	-0.2
Arm fat percentage (left)	0.3	1.0	3.5	-1.7	-0.1	-1.1	-1.8	-0.6	-0.6	1.9	-0.7	0.6	1.3	1.3	0.2	-1.6	-0.2	-0.0	0.5	-1.2	-0.6	0.3	-0.0
Commuting to job workplace: Walk	0.3	0.3	1.2	0.1	1.1	0.2	1.0	0.8	-0.1	-0.8	0.1	-0.5	0.1	-0.5	-0.8	-0.4	-0.2	0.2	-0.4	-0.0	-0.3	-0.6	-0.2
Medication: Aspirin	0.3	0.4	1.8	0.5	-0.1	0.5	0.7	1.0	0.4	0.6	0.4	0.4	-0.2	0.4	0.2	-0.2	0.3	0.6	1.1	0.5	1.3	0.6	0.8
Arm fat mass (left)	0.3	1.2	3.0	-1.7	-0.6	-1.7	-1.4	-1.4	-1.3	0.3	-0.9	-0.5	0.5	-0.2	-0.9	-1.6	-1.2	-0.5	1.2	-1.3	-0.0	0.3	1.1
Ever taken oral contraceptive pill	0.3	0.3	2.9	-0.0	-1.7	-0.2	-0.3	0.3	0.0	-0.3	-0.1	-0.2	0.7	0.1	0.9	0.4	-0.1	-0.3	0.2	0.3	0.5	0.3	0.7
High cholesterol (Self-reported)	0.3	0.6	4.4	-0.5	0.8	-0.3	-0.4	-0.6	0.3	-0.4	-0.4	0.7	0.2	0.6	-0.3	-0.7	0.2	0.9	1.1	0.4	0.7	2.1	1.1
Medication: Paracetamol	0.3	0.4	1.8	0.7	0.7	0.8	1.3	0.1	0.5	-0.4	1.1	0.4	0.1	0.2	-0.9	0.6	0.7	0.6	-1.0	0.4	0.1	-0.3	-0.5
Ever smoked	0.3	0.6	2.1	0.3	0.3	0.8	-0.0	-0.2	0.8	-0.4	0.4	0.6	0.4	1.5	0.6	-0.2	1.2	1.0	-1.4	0.3	-0.7	-0.7	-1.3
Fractured/broken bones in last 5 years	0.3	0.4	1.7	1.0	0.3	0.5	1.0	0.2	0.5	-0.6	1.0	0.3	-1.3	-0.3	0.1	0.6	0.4	0.2	-0.4	0.5	0.5	-0.9	0.3
Leg fat mass (left)	0.3	1.1	4.5	-1.3	-0.6	-1.5	-2.1	-1.4	-1.1	0.0	-0.8	-0.6	0.3	-0.4	-0.4	-1.1	-1.3	-0.2	1.6	-0.9	0.4	0.5	1.2
Rheumatoid Arthritis	0.2	0.3	1.9	-0.0	0.3	0.2	-1.1	0.1	-0.0	0.8	0.4	-0.1	0.4	0.1	0.4	-0.1	-0.6	-0.1	-1.0	-0.3	-0.6	-0.8	-1.4
Respiratory disease	0.2	0.4	1.5	0.1	-0.3	-0.1	0.3	-0.6	-0.7	-0.6	0.4	-1.2	-0.1	-1.0	-0.9	-0.2	-0.8	-0.4	1.1	-0.2	0.5	0.8	0.2
Chronotype (morning person)	0.2	0.5	2.1	-0.5	0.3	-0.3	-0.7	-0.4	-0.7	-0.8	-0.9	-0.6	0.5	-0.2	-0.6	-0.2	1.2	-0.6	-1.0	-0.9	-1.4	-0.6	-0.9
Sensitivity / hurt feelings	0.2	0.3	1.8	0.1	-0.6	-0.1	0.8	-0.5	-0.5	-0.8	0.1	-0.7	-0.4	-1.3	-0.6	0.3	-0.7	-0.2	-0.0	0.2	-0.4	-0.2	0.6
Waist circumference	0.2	0.9	2.9	-1.4	-0.2	-1.2	-1.5	-0.8	-1.1	1.4	-0.6	-0.4	0.7	0.4	0.7	-1.7	-0.5	-0.4	0.1	-1.4	-0.6	-0.7	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	1.4	0.2	-0.1	0.3	1.2	0.3	-0.0	1.1	1.1	-0.3	0.3	-0.2	1.1	-0.1	-0.6	-0.3	-0.4	-0.4	0.3	-0.1	-1.0
Had menopause	0.2	0.2	1.2	0.4	1.1	0.5	0.0	0.1	-0.2	0.7	0.6	-0.4	-0.2	0.1	-0.9	0.5	-0.2	0.4	-0.2	-0.0	0.2	-0.4	-0.8
Qualifications: None of the above	0.2	0.4	1.6	0.5	0.5	0.7	-1.3	-0.3	0.5	-0.2	1.0	-0.2	0.3	-0.2	0.8	-0.5	-0.2	1.1	-1.0	0.3	0.3	0.3	-0.4
Financial difficulties in last 2 years	0.2	0.3	1.6	0.2	-0.9	0.2	0.7	-0.0	0.1	-1.3	0.2	-0.5	0.1	-0.8	-0.4	0.0	-0.2	0.3	0.7	0.3	0.7	0.6	0.5
Heart attack	0.2	0.2	0.9	0.3	0.7	0.3	0.6	0.1	0.2	-0.5	0.0	0.0	-1.0	-0.2	0.9	-0.0	0.8	0.2	0.4	0.5	0.4	0.2	0.2
Father’s age at death	0.2	0.3	2.8	-0.4	0.2	-0.3	-0.1	-0.6	-0.1	-0.4	-0.9	0.2	0.1	-0.1	-1.7	0.5	0.3	-0.1	0.6	-0.0	-0.1	0.4	0.3
Medication: Cholesterol lowering	0.2	0.3	1.6	0.4	1.3	0.2	-0.6	0.2	0.2	-0.3	0.6	0.1	-0.8	-0.4	-0.8	-0.5	-0.2	0.6	0.1	0.6	0.5	0.4	0.8
Prospective memory result	0.2	0.3	1.2	0.4	-0.5	0.4	-0.8	0.5	0.5	-0.1	0.2	0.4	0.2	0.6	1.1	0.2	0.3	0.5	0.7	0.5	0.4	0.2	0.7
Standing height	0.2	1.8	5.7	2.0	1.0	1.0	0.8	0.6	0.9	-1.3	2.1	0.0	-0.6	-1.1	1.6	1.9	-0.2	1.4	-1.0	1.9	2.4	-0.0	1.1
Leg fat percentage (right)	0.2	0.6	3.6	-0.6	0.1	-0.6	-1.9	-0.6	-0.3	0.8	-0.2	0.3	0.0	0.5	0.4	-0.5	-0.8	0.5	1.6	-0.1	0.6	0.7	0.8
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.3	0.1	1.1	0.1	-0.4	-0.4	0.3	0.4	0.3	0.6	-0.1	-0.1	-0.7	0.1	0.0	0.2	0.7	0.2	0.6	0.5	0.0
Pulse rate, automated reading	0.2	0.5	2.1	-0.8	-0.1	-0.4	-1.0	-0.5	0.1	0.4	-1.3	0.3	-0.0	0.5	0.9	-0.0	1.2	-0.4	0.4	-0.3	0.5	1.5	0.9
Number of full sisters	0.2	0.3	1.4	-0.3	-0.5	-0.1	-0.6	-0.4	-0.2	-0.8	-0.3	-0.3	-0.3	-0.4	-0.8	0.1	-0.1	-0.5	-1.2	-0.4	-0.8	-0.9	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.5	0.7	-0.6	0.5	-0.5	0.3	0.6	0.5	1.1	0.5	-0.1	-0.2	1.2	0.5	0.3	0.2	-0.9	0.3	0.5	-0.5	-1.1
Diabetes diagnosed by doctor	0.2	0.4	1.6	0.3	-0.5	-0.2	-0.6	-0.5	-0.1	-0.3	-0.2	-0.8	-0.3	-0.7	-0.3	0.8	0.5	-0.1	1.2	0.4	0.8	0.5	1.3
Illnesses of father: None of the above (group 1)	0.2	0.3	1.8	0.3	0.2	0.2	0.8	0.6	0.3	0.7	0.1	0.2	0.5	0.4	0.8	0.7	1.3	-0.3	0.1	0.3	0.3	-0.3	0.3
Wears glasses or contact lenses	0.2	0.3	1.2	0.4	0.4	0.2	-0.4	0.9	0.1	-0.1	0.7	0.1	-0.6	-0.4	-0.7	-0.4	-1.1	0.6	-0.9	0.2	0.1	-0.0	0.2
Leg fat percentage (left)	0.2	0.6	4.5	-0.8	0.1	-0.8	-2.1	-0.7	-0.4	1.0	-0.4	0.2	0.2	0.5	0.2	-0.8	-0.7	0.3	1.3	-0.5	0.4	0.6	0.5
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.9	0.6	0.8	0.8	0.6	1.0	0.2	0.0	0.6	-0.1	-0.3	0.0	-0.3	0.2	-0.1	0.2	-0.4	0.4	0.3	-0.2	0.4
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.9	0.4	0.8	0.4	0.6	0.1	0.3	-0.3	0.1	0.1	-0.8	-0.0	1.0	-0.1	0.7	0.4	0.6	0.6	0.6	0.4	0.3
Hair Pigment	0.1	3.9	12.2	-2.7	-2.3	-2.6	-1.2	-2.7	-1.4	-0.0	-3.2	-0.4	1.2	0.6	-0.3	-1.5	-0.5	-0.5	3.5	-1.2	0.0	2.6	3.5
Trunk fat mass	0.1	0.5	2.6	-0.7	0.4	-0.5	-1.6	-0.4	-0.1	1.4	0.1	0.6	1.0	0.9	0.6	-0.8	-0.3	0.7	0.5	-0.3	0.4	0.2	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.9	-0.3	-0.1	-0.2	-0.2	-0.0	-0.1	-0.4	-0.0	0.1	0.8	0.3	-0.4	-1.0	-0.0	0.3	-0.3	-0.1	-0.2	0.1	0.0
Whole body fat mass	0.1	0.6	2.8	-1.1	0.0	-1.0	-1.7	-0.7	-0.5	0.9	-0.4	0.2	1.0	0.6	0.2	-1.1	-0.6	0.4	1.0	-0.6	0.4	0.4	0.7
Alcohol intake frequency.	0.1	0.3	2.1	-0.3	0.4	-0.0	-1.5	-0.4	-0.0	0.8	-0.2	0.1	-0.1	-0.1	-0.8	-0.5	0.5	0.3	0.1	-0.1	0.3	0.7	0.4

Hub : Genes

ATG7

Models

Trait associations