[Hub]/) : Traits : Medication: Blood pressure : →

chr1:11,181,327-12,600,396

Best TWAS P=6.22e-13 · Best GWAS P=1.16e-12 conditioned to 0.000354

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts CLCN6 0.08 0.02 enet 17 0.05 1.6e-04 -7.1 -6.0 2.6e-09 0.75 0.01 0.99 FALSE
2 GTEx Skin Not Sun Exposed Suprapubic CLCN6 0.12 0.03 lasso 3 0.04 3.3e-03 -4.1 -5.8 5.8e-09 0.83 0.02 0.93 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma CLCN6 0.06 0.06 blup 104 0.06 5.0e-12 -4.5 -6.6 4.6e-11 0.75 0.26 0.74 FALSE
4 The Cancer Genome Atlas Colon Adenocarcinoma CLCN6 0.14 0.05 blup 104 0.09 1.2e-05 -7.0 -5.1 2.8e-07 0.81 0.01 0.98 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CLCN6 0.04 0.06 lasso 2 0.05 1.1e-06 -4.5 -5.3 1.4e-07 0.69 0.10 0.90 FALSE
6 The Cancer Genome Atlas Lung Adenocarcinoma CLCN6 0.06 0.04 blup 104 0.04 5.2e-06 -7.1 -6.4 1.5e-10 0.91 0.01 0.99 FALSE
7 The Cancer Genome Atlas Prostate Adenocarcinoma CLCN6 0.10 0.07 blup 104 0.07 3.9e-08 -6.6 -7.2 6.2e-13 0.59 0.11 0.88 TRUE
8 The Cancer Genome Atlas Stomach Adenocarcinoma CLCN6 0.07 0.04 blup 104 0.05 2.4e-04 -7.0 -6.0 2.6e-09 0.94 0.01 0.99 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma NPPA 0.06 0.03 enet 4 0.04 7.6e-04 -6.6 5.6 2.4e-08 -0.45 0.10 0.24 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma CLCN6 0.08 0.02 blup 104 0.05 2.5e-05 -3.1 -5.2 1.7e-07 0.64 0.16 0.83 FALSE