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chr1:11,181,327-12,600,396

Best TWAS P=6.22e-13 · Best GWAS P=1.16e-12 conditioned to 0.000354

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	The Cancer Genome Atlas	Prostate Adenocarcinoma	CLCN6	0.10	0.07	blup	104	0.07	3.9e-08	-6.6	-7.2	6.2e-13	0.59	0.11	0.88	TRUE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	CLCN6	0.06	0.06	blup	104	0.06	5.0e-12	-4.5	-6.6	4.6e-11	0.75	0.26	0.74	FALSE
6	The Cancer Genome Atlas	Lung Adenocarcinoma	CLCN6	0.06	0.04	blup	104	0.04	5.2e-06	-7.1	-6.4	1.5e-10	0.91	0.01	0.99	FALSE
1	GTEx	Cells Transformed fibroblasts	CLCN6	0.08	0.02	enet	17	0.05	1.6e-04	-7.1	-6.0	2.6e-09	0.75	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Stomach Adenocarcinoma	CLCN6	0.07	0.04	blup	104	0.05	2.4e-04	-7.0	-6.0	2.6e-09	0.94	0.01	0.99	FALSE
2	GTEx	Skin Not Sun Exposed Suprapubic	CLCN6	0.12	0.03	lasso	3	0.04	3.3e-03	-4.1	-5.8	5.8e-09	0.83	0.02	0.93	FALSE
9	The Cancer Genome Atlas	Stomach Adenocarcinoma	NPPA	0.06	0.03	enet	4	0.04	7.6e-04	-6.6	5.6	2.4e-08	-0.45	0.10	0.24	FALSE
5	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CLCN6	0.04	0.06	lasso	2	0.05	1.1e-06	-4.5	-5.3	1.4e-07	0.69	0.10	0.90	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	CLCN6	0.08	0.02	blup	104	0.05	2.5e-05	-3.1	-5.2	1.7e-07	0.64	0.16	0.83	FALSE
4	The Cancer Genome Atlas	Colon Adenocarcinoma	CLCN6	0.14	0.05	blup	104	0.09	1.2e-05	-7.0	-5.1	2.8e-07	0.81	0.01	0.98	FALSE