TWAS hub - NPPA

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Testis	0.3650	0.0730	1.2e-07	0.234	NA	0.229	NA	0.240	9.5e-11	NA	1.6e-10	NA	5.0e-11
2	METSIM	Adipose	0.1154	0.0280	1.2e-07	0.092	0.060	0.087	0.091	0.096	1.1e-13	2.6e-09	6.1e-13	1.9e-13	3.0e-14
3	ROSMAP	Brain Pre-frontal Cortex	0.0930	0.0295	1.1e-04	0.060	0.025	0.090	0.068	0.086	3.8e-08	2.7e-04	1.2e-11	3.8e-09	3.3e-11
4	TCGA	Breast Invasive Carcinoma	0.0511	0.0204	2.9e-08	0.049	0.044	0.040	NA	0.046	2.3e-10	2.5e-09	1.3e-08	NA	8.9e-10
5	TCGA	Colon Adenocarcinoma	0.0580	0.0350	8.0e-03	0.006	0.000	0.001	NA	0.007	1.4e-01	3.2e-01	2.7e-01	NA	1.3e-01
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.1024	0.0486	8.8e-06	0.073	0.058	0.056	NA	0.066	1.3e-08	4.4e-07	5.8e-07	NA	6.5e-08
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0800	0.0400	1.5e-03	0.024	0.027	0.015	NA	0.015	1.5e-02	1.0e-02	4.4e-02	NA	4.7e-02
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.0730	0.0360	6.7e-04	0.005	0.040	0.021	NA	0.015	1.5e-01	9.7e-04	1.3e-02	NA	3.4e-02
9	TCGA	Prostate Adenocarcinoma	0.1113	0.0402	5.5e-09	0.071	0.100	0.112	NA	0.102	6.6e-08	1.2e-10	1.0e-11	NA	8.6e-11
10	TCGA	Stomach Adenocarcinoma	0.0590	0.0300	6.2e-03	0.032	0.032	0.039	NA	0.037	2.0e-03	2.1e-03	7.6e-04	NA	1.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Systolic Blood Pressure	12.1	60.8	116.6	8.5	6.4	7.5	5.0	10.8	7.4	5.7	7.5	6.2	10.7
Cardiovascular Disease	10.6	35.0	70.2	6.8	5.3	4.4	4.3	7.8	6.0	3.2	5.5	5.4	8.4
Birth weight of first child	8.3	15.1	26.0	-4.2	-2.9	-2.5	-3.1	-4.1	-3.1	-4.1	-4.8	-5.1	-4.0
Hypertension (Self-reported)	8.0	22.1	46.4	5.4	4.0	4.8	3.2	6.2	4.5	2.3	4.2	3.9	6.8
High blood pressure	7.4	20.7	44.9	5.2	4.0	5.0	3.0	6.1	4.3	2.1	3.8	3.4	6.7
Medication: Amlodipine	7.2	10.1	19.5	3.2	2.5	3.0	2.3	3.9	2.9	3.2	4.4	3.0	2.8
Medication: Blood pressure	7.0	13.4	31.1	4.3	3.4	3.5	2.8	4.5	3.7	0.9	2.9	3.1	5.6
Medication: Blood pressure	6.0	10.6	19.0	3.7	2.2	3.9	2.3	3.9	2.7	2.8	3.1	2.7	4.4
Vascular/heart problems diagnosed by doctor	5.8	15.8	37.7	-4.4	-3.6	-4.3	-2.4	-5.4	-4.0	-1.4	-2.8	-2.9	-6.1
Type 2 Diabetes (T2D) (2012)	5.7	6.6	8.5	2.8	2.8	0.9	2.9	2.9	2.5	2.6	2.7	2.8	2.2
Mother’s age at death	5.6	7.0	11.7	-3.0	-2.4	-1.3	-2.5	-3.4	-2.6	-2.2	-3.0	-2.6	-2.8
Medication for cholesterol, blood pressure or diabetes	5.4	9.0	15.4	-3.3	-2.2	-3.7	-2.1	-3.4	-2.7	-2.9	-2.5	-2.7	-3.9
Back pain experienced in last month	5.1	7.4	9.5	-3.1	-3.0	-1.9	-2.9	-2.7	-2.7	-2.1	-2.8	-2.9	-3.0
Number of children fathered	4.4	5.0	7.0	-2.6	-2.3	-1.5	-2.1	-2.6	-2.5	-2.2	-2.1	-1.8	-2.1
Hip circumference	4.3	18.5	25.5	-4.4	-4.3	-1.7	-3.6	-5.0	-4.7	-3.8	-5.0	-5.0	-4.3
Systolic blood pressure, automated reading	4.2	12.1	29.7	3.9	1.9	4.2	1.4	5.0	2.5	2.7	2.9	2.2	5.5
Townsend deprivation index at recruitment	4.1	5.8	10.1	2.5	1.9	1.9	2.0	2.9	2.2	3.0	3.2	2.1	2.0
Falls in the last year	4.0	5.4	7.0	-2.3	-2.6	-2.0	-2.3	-2.6	-2.6	-1.3	-2.3	-2.5	-2.5
Medication: Atenolol	3.9	4.8	7.4	2.6	2.1	2.7	1.4	2.7	2.3	1.9	1.5	1.2	2.7
Medication: Gliclazide	3.9	4.4	9.2	2.8	2.1	2.2	2.4	2.1	1.9	1.3	1.0	1.1	3.0
High blood pressure (siblings)	3.8	5.5	19.3	2.9	1.6	2.4	1.7	2.4	1.5	-0.4	1.6	2.3	4.4
Schizophrenia vs Biploar Disorder	3.5	4.7	6.5	-2.6	-2.0	-0.9	-2.3	-2.2	-2.2	-2.1	-2.4	-2.5	-2.0
Rheumatoid Arthritis	3.5	4.9	7.3	-2.4	-2.1	-1.8	-2.0	-2.3	-2.1	-2.2	-2.1	-2.7	-2.2
Medication: Ibuprofen (e.g. Nurofen)	3.5	4.5	9.0	2.4	1.7	1.6	2.4	1.7	1.8	3.0	2.1	2.3	1.6
Leg fat percentage (left)	3.5	12.7	20.7	-3.5	-4.1	-1.4	-3.0	-4.5	-4.5	-2.4	-4.1	-3.7	-3.2
Neuroticism (2016)	3.4	5.0	9.6	2.3	3.1	2.0	2.5	2.3	2.9	1.6	1.7	1.7	1.4
Medication: Ibuprofen	3.4	4.0	8.5	2.2	1.7	1.3	2.3	1.6	1.7	2.9	1.9	2.2	1.6
Fasting Glucose	3.3	4.0	7.2	-2.1	-1.5	-1.5	-2.4	-1.6	-1.2	-2.7	-2.3	-2.6	-1.5
Allergy	3.1	7.0	13.1	-2.8	-2.7	-1.3	-2.5	-3.3	-2.7	-1.6	-2.8	-2.4	-3.6
High blood pressure (mother)	3.0	4.3	9.1	2.1	0.9	3.0	1.6	1.7	0.8	1.8	2.4	2.4	2.6
Arm fat percentage (right)	3.0	11.8	17.4	-3.3	-3.8	-1.5	-2.9	-4.0	-4.1	-2.9	-4.2	-4.0	-2.9
Asthma	3.0	5.9	8.6	2.6	2.3	1.2	2.5	2.9	2.1	2.8	2.7	1.7	2.7
Medication: Cholesterol lowering	3.0	4.6	7.7	2.4	1.8	1.8	1.6	2.4	2.1	2.8	1.5	2.1	2.6
Chronic bronchitis/emphysema (mother)	2.9	3.4	7.9	1.7	0.9	1.8	1.2	1.7	1.3	2.8	2.5	2.2	1.4
Body fat percentage	2.9	11.5	18.6	-3.2	-3.8	-1.6	-2.7	-4.1	-4.3	-2.5	-4.0	-3.7	-2.9
Leg fat percentage (right)	2.9	10.4	17.1	-3.1	-3.7	-0.6	-2.6	-4.1	-4.1	-2.1	-4.0	-3.4	-2.9
Seen a psychiatrist for nerves, anxiety, tension or depression	2.9	3.7	6.7	2.2	2.2	2.6	2.4	1.9	2.2	1.6	1.0	1.1	1.4
Diastolic blood pressure, automated reading	2.9	8.9	18.7	2.8	0.9	4.3	0.9	4.1	1.6	3.7	2.3	1.9	4.3
Asthma (self-reported)	2.8	5.6	9.2	2.4	2.2	1.1	2.4	2.8	2.1	3.0	2.8	1.8	2.3
HbA1C	2.7	3.0	9.5	-2.4	-1.4	-0.2	-2.2	-1.6	-1.3	-1.4	-0.9	-0.7	-3.1
Pulse wave Arterial Stiffness index	2.7	3.2	6.8	2.0	1.2	2.3	1.5	2.3	1.4	0.8	1.5	1.4	2.6
Pulse wave peak to peak time	2.7	3.2	6.2	-2.0	-1.3	-2.3	-1.4	-2.3	-1.5	-0.8	-1.5	-1.4	-2.5
Allergy or Eczema	2.6	6.7	12.8	2.7	2.4	0.9	2.2	3.3	2.4	1.5	3.0	2.7	3.6
Hayfever, allergic rhinitis or eczema	2.6	5.6	10.1	2.5	2.2	1.3	2.0	3.1	2.4	1.1	2.5	2.4	3.2
Hayfever/allergic rhinitis (self-reported)	2.6	3.5	9.3	2.1	1.6	-0.0	1.6	2.1	1.7	0.5	2.0	2.1	3.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.6	3.0	5.1	-2.0	-1.2	-1.7	-1.5	-1.3	-1.3	-1.7	-1.8	-2.3	-2.1
Number of treatments/medications taken	2.5	4.6	11.6	2.2	1.6	3.4	1.7	2.0	1.5	2.1	1.8	1.8	2.6
Trunk fat percentage	2.5	9.9	16.3	-3.0	-3.6	-1.6	-2.6	-3.7	-4.0	-2.5	-3.6	-3.5	-2.6
Medication: Lisinopril	2.4	3.1	6.5	2.3	1.5	1.1	1.1	2.4	2.0	0.7	1.5	1.3	2.5
Supplements: Zinc	2.3	2.5	3.6	-1.3	-1.5	-1.4	-1.0	-1.9	-1.6	-1.4	-1.9	-1.8	-1.8
Pulse wave reflection index	2.3	2.8	5.3	1.5	1.2	1.5	1.3	2.1	1.4	2.3	2.0	1.6	1.4
Medication for cholesterol	2.3	3.6	9.0	-2.4	-1.6	-1.7	-1.4	-2.1	-1.7	-0.4	-1.6	-1.9	-3.0
Medication: Lansoprazole	2.2	2.5	5.0	1.6	2.1	1.1	1.2	2.1	2.2	1.3	1.1	0.8	1.3
Arm fat percentage (left)	2.2	8.8	13.5	-2.9	-3.3	-1.1	-2.5	-3.4	-3.7	-2.2	-3.6	-3.5	-2.5
Medication: Metformin	2.1	2.9	8.3	2.3	1.3	1.7	1.9	1.7	1.3	0.7	0.7	1.3	2.9
Alcohol usually taken with meals	2.1	3.4	12.4	-1.4	-1.0	-2.8	-1.4	-1.4	-1.2	-3.5	-1.8	-1.6	-0.6
Arm fat mass (right)	2.1	8.7	12.7	-2.8	-3.2	-1.0	-2.5	-3.3	-3.6	-2.2	-3.6	-3.5	-2.7
Fractured/broken bones in last 5 years	2.1	2.7	6.3	-2.1	-1.8	-0.5	-1.5	-1.3	-1.8	-0.3	-1.2	-2.1	-2.5
Trunk fat mass	2.0	8.5	13.9	-2.8	-3.3	-1.3	-2.4	-3.4	-3.7	-2.1	-3.4	-3.3	-2.6
Osteoporosis (self-reported)	2.0	2.5	3.8	-1.9	-1.9	-1.0	-1.8	-1.2	-1.5	-1.3	-1.2	-1.7	-1.9
Risk taking	2.0	2.9	4.8	-2.2	-2.0	-0.5	-2.0	-2.0	-1.8	-0.8	-1.4	-1.5	-2.1
Body Mass Index (BMI) (2010)	1.9	2.6	3.7	-1.7	-1.4	-1.4	-1.5	-1.6	-1.5	-1.8	-1.9	-1.8	-1.4
Medication: Ramipril	1.9	2.5	5.9	1.7	1.4	2.0	1.0	1.9	1.6	0.9	0.7	1.1	2.4
Whole body fat mass	1.9	7.9	12.7	-2.6	-3.1	-1.0	-2.3	-3.3	-3.6	-2.0	-3.4	-3.3	-2.4
Chest pain or discomfort	1.9	2.7	5.2	1.7	1.9	0.9	1.3	2.3	2.2	1.3	1.9	0.8	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	6.6	1.8	0.6	1.2	1.3	1.1	0.7	2.6	1.6	1.6	1.5
Blood Red Count	1.8	17.3	25.5	-4.4	-4.1	-1.7	-2.8	-5.0	-4.8	-4.0	-4.5	-4.9	-4.2
Angina	1.8	2.4	4.5	1.7	2.1	1.8	1.0	1.7	2.1	1.5	-0.1	0.1	1.7
Body mass index (BMI)	1.8	7.7	12.1	-2.7	-3.0	-0.3	-2.4	-3.2	-3.3	-1.7	-3.4	-3.5	-2.6
Waist circumference	1.8	6.6	11.7	-2.5	-2.7	-0.1	-2.1	-2.8	-3.0	-1.7	-3.4	-3.1	-2.3
High cholesterol (Self-reported)	1.8	3.2	6.1	1.8	1.2	1.6	0.8	2.0	1.9	2.5	1.6	2.0	2.0
Leg fat mass (left)	1.8	7.2	11.5	-2.5	-3.0	-0.9	-2.2	-3.2	-3.4	-1.6	-3.2	-3.1	-2.5
Leg fat mass (right)	1.7	6.4	10.3	-2.4	-2.9	-0.3	-2.0	-3.1	-3.2	-1.5	-3.2	-3.0	-2.3
Number of self-reported non-cancer illnesses	1.7	2.9	7.0	1.6	1.0	2.6	1.0	2.1	1.3	1.2	1.5	1.4	2.3
Medication: Atorvastatin	1.7	2.2	5.5	1.7	0.9	1.8	1.1	1.0	1.0	2.3	1.0	1.6	1.5
Alcohol drinker status: Never	1.7	2.0	3.5	-1.6	-1.3	-1.1	-1.7	-1.5	-1.4	-1.1	-1.9	-1.2	-1.1
Bipolar Disorder (2018)	1.6	2.5	4.7	1.9	0.8	0.3	1.0	1.7	1.2	2.2	2.1	2.0	1.6
Ever used hormone-replacement therapy (HRT)	1.6	2.0	5.5	-1.4	-2.2	-0.7	-0.9	-1.9	-2.3	0.3	-0.2	-0.2	-1.4
Supplements: Glucosamine	1.6	2.1	3.1	1.7	1.0	1.2	1.6	1.5	1.2	0.6	1.8	1.7	1.6
Knee pain experienced in last month	1.6	2.6	4.0	1.7	1.5	1.0	1.2	2.0	1.8	1.8	2.0	1.3	1.3
Arm fat mass (left)	1.6	6.7	10.5	-2.5	-2.9	-0.4	-2.2	-2.9	-3.2	-1.8	-3.2	-3.2	-2.3
Severe depression (siblings)	1.5	1.6	5.1	1.3	2.1	0.2	1.1	1.4	2.3	-0.2	0.9	0.4	0.9
Weight	1.5	7.4	10.8	-2.8	-2.9	-0.5	-2.4	-3.0	-3.1	-1.9	-3.2	-3.3	-2.8
Number of full brothers	1.5	1.8	7.0	1.0	1.0	2.6	0.5	0.8	1.3	1.0	1.8	1.4	0.8
Bipolar Disorder (2011)	1.4	1.3	5.7	0.0	0.0	0.0	0.2	1.3	0.9	1.3	2.4	1.6	0.6
BMI	1.4	7.9	15.2	-2.6	-2.9	-0.9	-2.2	-3.0	-3.1	-2.0	-3.6	-3.9	-2.8
Waist Hip Ratio (WHR)	1.4	6.1	10.3	3.0	2.1	1.3	2.7	2.6	1.8	2.3	2.2	2.9	3.2
Loud music exposure frequency	1.4	1.6	3.0	1.5	1.5	0.4	0.9	1.6	1.7	0.8	1.4	0.8	1.2
Ever had bowel cancer screening	1.4	1.6	2.7	-1.6	-1.4	0.0	-1.6	-1.5	-1.3	-0.6	-1.1	-1.1	-1.5
Breast Cancer	1.3	3.1	9.5	-2.2	-1.8	-0.7	-2.1	-1.4	-1.6	-0.3	-0.8	-1.9	-3.1
Stomach or abdominal pain in last month	1.3	1.6	3.2	1.5	1.3	-0.1	1.3	1.0	1.2	1.8	1.4	1.5	0.9
Qualifications: None of the above	1.3	2.7	7.0	2.0	1.0	2.6	1.7	0.7	0.7	1.9	1.2	1.7	1.8
Alcohol intake versus 10 years previously	1.3	1.9	10.1	1.1	0.3	1.9	0.9	1.1	0.6	3.2	1.2	0.7	0.5
Angina (self-reported)	1.3	1.7	3.6	1.4	1.9	1.3	0.6	1.5	1.9	1.1	-0.3	-0.2	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.5	3.3	-1.4	-0.7	-0.4	-1.3	-1.1	-0.9	-1.3	-1.5	-1.8	-1.3
Lupus	1.2	1.9	4.6	1.0	1.1	-0.1	1.0	2.1	1.4	1.6	2.1	1.3	0.4
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	2.5	-1.4	-1.0	0.3	-1.6	-0.9	-0.7	-1.1	-1.2	-1.6	-1.4
Illnesses of siblings	1.2	1.6	7.5	-1.5	-0.5	-1.2	-0.6	-1.1	-0.5	0.7	-0.7	-1.4	-2.7
Mouth/teeth dental problems: Dentures	1.2	2.0	3.2	-1.4	-1.5	-1.8	-1.0	-1.4	-1.8	-1.5	-1.1	-1.3	-1.0
Miserableness	1.2	2.0	3.6	-1.8	-0.9	-0.1	-1.6	-1.4	-0.9	-1.6	-1.6	-1.9	-1.5
Illnesses of father: High blood pressure	1.2	1.5	5.2	1.2	0.2	1.0	0.7	1.3	0.5	0.7	1.5	1.6	2.3
Age at First Birth	1.1	1.6	6.3	0.9	1.1	0.4	0.8	1.5	1.3	2.5	0.9	1.1	1.0
Fed-up feelings	1.1	2.1	3.0	1.2	1.6	0.6	1.6	1.7	1.5	1.7	1.7	1.3	0.9
Hair/balding pattern: Pattern 2	1.1	1.3	2.5	1.2	0.9	-0.5	1.4	1.1	0.7	1.3	1.6	1.2	1.3
Taking other prescription medications	1.0	1.5	3.6	1.1	1.3	1.9	1.1	0.8	1.0	1.2	0.6	1.0	1.5
Exposure to tobacco smoke at home	1.0	1.2	2.2	-0.7	-1.4	1.2	-0.9	-0.9	-1.2	1.5	-0.9	-1.0	-0.8
Eye problems/disorders: None of the above	1.0	1.2	2.6	1.2	1.5	-0.5	1.3	1.6	1.5	0.5	0.3	0.1	0.9
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	2.5	1.1	1.6	0.9	1.2	1.1	1.3	1.4	0.6	0.5	0.7
Supplements: Vitamin C	1.0	1.1	2.8	-0.9	-0.9	0.3	-0.5	-1.2	-1.1	-1.6	-1.7	-1.2	-0.1
Qualifications: nursing, teaching	1.0	1.5	2.3	-1.4	-1.3	-1.3	-1.1	-1.5	-1.5	-1.2	-0.9	-0.9	-1.2
Eye problems/disorders: Cataract	1.0	1.1	2.1	-1.1	-1.4	-1.1	-1.4	-1.3	-1.4	-0.9	-0.4	-0.1	-0.6
Respiratory disease	0.9	2.0	3.1	1.5	1.3	0.4	1.7	1.5	1.0	1.3	1.7	1.4	1.8
Type 2 Diabetes (T2D) (2018)	0.9	1.6	4.5	1.8	0.8	0.9	1.1	1.3	0.9	0.9	1.2	1.1	2.1
Sensitivity / hurt feelings	0.9	1.5	2.9	-1.6	-1.6	-0.5	-1.7	-1.4	-1.3	-0.4	-0.4	-0.7	-1.7
Frequency of depressed mood in last 2 weeks	0.9	1.2	3.2	0.8	1.8	1.2	1.1	1.3	1.6	0.7	0.9	0.6	0.4
Diabetes (mother)	0.9	1.1	5.1	0.6	-0.2	2.3	0.8	0.3	-0.2	1.2	1.1	1.2	0.8
Average weekly fortified wine intake	0.9	1.0	1.6	1.2	1.0	0.3	0.8	1.1	1.1	-0.0	1.1	1.3	1.3
Qualifications: CSEs or equivalent	0.9	1.2	2.0	-1.4	-1.2	-0.8	-1.3	-1.3	-1.3	-0.4	-0.4	-0.6	-1.4
Serious illness, injury or assault to yourself	0.9	1.0	2.7	-1.4	-1.1	0.6	-1.1	-1.0	-1.1	0.1	-0.6	-0.6	-1.6
Prospective memory result	0.9	1.1	2.7	1.2	1.0	1.7	0.7	1.1	1.5	0.5	0.5	0.3	1.1
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	1.9	1.0	0.9	0.2	0.6	1.3	1.0	1.3	1.3	0.9	1.4
Average weekly red wine intake	0.9	1.3	3.1	-1.0	-0.7	-0.7	-1.0	-0.7	-0.5	-1.7	-1.7	-1.8	-0.4
Diabetes diagnosed by doctor	0.9	1.5	4.2	1.6	0.5	1.7	1.2	0.9	0.5	1.2	0.4	1.0	2.0
Guilty feelings	0.9	1.4	2.5	-1.2	-1.2	-1.2	-1.3	-1.6	-1.0	-0.1	-1.1	-0.8	-1.3
Wears glasses or contact lenses	0.9	1.0	5.2	-0.3	-0.7	0.3	-0.0	-1.2	-1.0	-2.3	-1.1	0.2	0.7
Medication: Bendroflumethiazide	0.9	1.3	3.6	1.1	0.7	1.7	0.4	1.4	0.8	0.1	1.2	0.6	1.9
Chronotype (morning person)	0.8	1.8	4.8	-1.3	-1.1	-1.1	-1.5	-1.2	-1.1	-2.2	-1.3	-1.3	-1.1
Chronic bronchitis/emphysema (father)	0.8	0.9	3.2	-0.7	-0.5	-1.2	-0.4	-0.8	-0.5	-0.7	-1.8	-1.4	-0.8
Had menopause	0.8	1.0	2.2	-0.6	-0.9	0.9	-0.2	-1.2	-1.1	-1.4	-1.5	-0.9	-0.6
Time employed in main current job	0.8	0.9	2.2	0.6	1.4	0.8	0.9	0.6	0.9	0.2	1.5	1.4	0.4
Noisy workplace	0.8	0.9	4.1	-0.6	-0.5	2.0	-0.8	-1.4	-0.6	-0.5	-0.9	-0.3	-0.7
Illnesses of mother	0.8	1.0	2.9	-0.7	-0.1	-1.7	-1.1	-0.4	0.1	-1.6	-0.9	-1.1	-0.8
Emphysema/chronic bronchitis	0.8	0.9	2.0	-1.2	-0.3	-0.6	-0.8	-0.9	-0.6	0.2	-0.9	-1.4	-1.4
Medication: Seretide 50 evohaler	0.8	0.9	3.0	-1.2	-0.4	0.1	-0.9	-0.9	-0.4	-0.3	-1.1	-1.7	-1.1
Commuting to job workplace: Walk	0.8	0.8	4.3	1.0	0.4	2.1	0.7	0.0	0.5	-0.3	-0.6	0.4	1.3
Number of operations (self-reported)	0.8	1.1	2.2	-1.0	-1.3	-0.1	-0.8	-1.2	-1.5	-1.2	-1.1	-1.1	-0.7
Bipolar Disorder or Schizophrenia	0.7	1.7	5.6	1.1	0.4	-0.5	0.3	1.6	0.7	1.8	2.4	1.6	0.9
Ever had hysterectomy (womb removed)	0.7	0.8	2.5	-1.1	-0.9	0.0	-0.4	-1.2	-1.1	0.6	-0.2	0.1	-1.6
Hand grip strength (right)	0.7	2.0	6.5	-2.0	-1.0	-1.7	-1.5	-1.3	-1.0	-0.9	-0.2	-0.6	-2.5
Forced vital capacity (FVC)	0.7	2.8	7.2	-2.0	-1.4	-2.7	-1.4	-1.4	-1.2	-1.1	-0.9	-1.1	-2.4
Medication: Simvastatin	0.7	1.1	2.4	1.0	0.7	1.5	0.3	1.2	1.0	0.9	0.6	0.8	1.5
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	5.6	-1.0	-0.5	-2.4	-0.8	-0.3	-0.4	-1.1	-0.7	-1.0	-1.0
Wheeze or whistling in the chest in last year	0.7	1.3	2.9	-1.3	-1.1	0.3	-1.1	-1.0	-1.1	0.3	-0.4	-1.6	-1.7
Medication: Omeprazole	0.7	0.9	3.7	-0.1	-0.8	1.9	-0.6	-1.0	-0.7	0.5	-1.1	-0.9	-0.0
Smoking status: Current	0.7	1.1	4.3	0.7	1.0	0.7	0.8	0.8	1.1	2.1	1.5	0.5	-0.6
Medication: Paracetamol	0.7	1.1	2.7	-1.2	-0.6	-0.9	-1.2	-0.8	-0.8	-0.2	-0.9	-1.6	-1.4
Myopia	0.7	1.1	3.2	1.4	1.0	0.3	0.9	1.2	1.2	-0.1	0.4	0.8	1.8
Basal cell carcinoma (self-reported)	0.7	0.9	4.2	0.5	0.5	2.0	0.7	0.9	0.8	0.6	0.6	0.6	1.0
Alcohol drinker status: Previous	0.7	0.9	2.8	1.1	0.7	0.5	0.6	1.2	1.0	-0.1	1.7	0.7	0.7
Alzheimer’s Disease (including proxy)	0.6	0.9	6.2	-0.3	0.5	-2.5	-0.3	0.6	0.4	-0.6	1.2	-0.3	-0.5
Prostate Cancer	0.6	0.8	1.6	0.8	0.8	-1.0	0.4	1.2	0.9	1.2	1.3	0.6	0.6
Blood Platelet Count	0.6	7.0	43.2	-0.3	-0.9	4.1	-1.1	0.5	0.3	6.6	0.2	2.6	-1.1
Lung FVC	0.6	3.2	9.2	-2.1	-1.4	-2.5	-1.3	-1.8	-1.5	-0.6	-1.0	-1.1	-3.0
Average weekly spirits intake	0.6	0.7	4.5	0.7	-0.0	2.1	0.7	-0.1	-0.1	0.9	0.2	0.7	0.6
Current tobacco smoking	0.6	0.9	3.4	0.6	0.8	0.5	0.7	0.7	0.9	1.9	1.5	0.5	-0.6
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.5	-0.1	-0.3	1.6	-0.4	-0.4	-0.0	-0.2	-1.4	-0.9	0.6
Number of incorrect matches in round	0.6	1.0	2.9	1.3	0.6	0.2	1.7	0.6	0.3	1.2	0.6	1.2	1.1
Hearing difficulty/problems with background noise	0.6	0.9	2.8	-1.0	-1.0	0.7	-0.7	-1.7	-1.3	-0.7	-0.2	0.1	-1.1
Had other major operations	0.6	0.8	1.7	-0.7	-0.5	-1.2	-0.3	-0.8	-0.7	-0.7	-1.0	-1.1	-1.3
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	6.7	-1.7	-1.1	-2.6	-1.2	-1.1	-0.9	-0.9	-0.6	-0.9	-1.8
Neck or shoulder pain in last month	0.6	0.9	2.1	-1.1	-0.9	-0.3	-1.5	-0.9	-0.7	-0.9	-1.0	-0.9	-0.9
Commuting to job workplace: Car/motor vehicle	0.6	0.6	2.0	-1.1	-0.7	-1.4	-0.5	-0.4	-0.7	0.0	-0.3	-1.0	-0.9
Loneliness, isolation	0.6	0.8	1.7	0.9	1.3	0.5	1.2	1.1	1.0	0.5	0.8	0.5	0.7
Long-standing illness, disability or infirmity	0.6	0.9	2.1	-1.1	-0.9	0.4	-1.5	-0.7	-0.6	-0.1	-1.1	-1.4	-1.0
Medication: Aspirin	0.6	0.7	3.3	0.7	0.3	1.8	-0.4	0.8	0.7	-0.2	-0.3	0.1	1.4
Average weekly champagne plus white wine intake	0.6	0.8	1.9	1.0	0.7	-0.4	1.1	0.5	0.7	-0.5	0.9	1.3	1.4
Commuting to job workplace: Public transport	0.6	0.8	2.7	-0.7	-0.7	-0.1	-0.9	-0.5	-0.6	-1.7	-1.1	-1.1	-0.2
Heart disease (siblings)	0.6	0.7	2.0	0.7	0.6	1.4	0.6	0.8	0.7	0.7	0.9	1.0	0.9
Pack years of smoking	0.6	0.9	2.0	-0.7	-1.1	-0.5	-0.8	-1.4	-1.3	-1.2	-0.8	-0.6	-0.4
Worry (Nagel 2018)	0.5	1.1	2.3	1.1	1.5	0.3	1.2	1.2	1.4	0.2	0.2	-0.2	1.5
Alzheimer’s Disease (in mother)	0.5	0.6	4.0	0.4	0.7	-2.0	0.3	0.6	0.7	-0.2	0.8	0.1	0.2
Crohns Disease (2017)	0.5	1.2	4.9	0.8	0.6	1.6	0.6	0.6	0.3	2.2	0.7	1.1	1.0
Crohns Disease (2012)	0.5	0.8	2.1	1.1	0.1	0.5	0.9	0.5	0.0	1.4	0.7	0.9	1.4
Mean Putamen Volume	0.5	0.6	1.8	-0.6	-0.5	0.4	-1.0	-0.6	-0.7	-1.4	-1.0	-0.9	-0.2
Hypothyroidism (self reported)	0.5	1.2	2.5	-1.2	-1.2	-0.3	-0.7	-1.6	-1.4	0.3	-1.1	-1.0	-1.2
Relative age of first facial hair	0.5	1.0	2.2	-1.3	-1.3	-0.7	-0.8	-1.2	-1.5	0.7	-0.3	-0.2	-1.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.0	-0.3	-0.6	1.4	-0.1	-0.8	-0.5	-1.0	-1.1	-0.9	-0.1
Medication: Co-codamol	0.5	0.6	1.3	-1.1	-0.5	0.3	-0.8	-0.9	-0.5	-0.4	-0.9	-0.4	-1.1
Sitting height	0.5	3.8	6.4	-2.3	-1.7	-2.0	-2.5	-1.8	-1.5	-1.7	-1.5	-1.6	-2.5
Hair/balding pattern: Pattern 3	0.5	0.7	2.3	-0.8	0.1	0.8	-0.2	-0.6	-0.0	-0.7	-1.5	-1.1	-1.1
Lung cancer (father)	0.5	0.6	1.3	-0.9	-0.8	-0.2	-1.1	-0.5	-0.8	0.4	-0.6	-0.8	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	6.2	-1.4	-1.0	-2.5	-1.1	-1.0	-0.8	-1.5	-0.4	-0.8	-1.5
Medication: Paracetamol	0.5	0.8	1.5	-1.0	-0.6	-1.0	-0.9	-0.8	-0.8	0.3	-0.5	-1.2	-1.1
Glaucoma (self-reported)	0.5	0.6	1.5	0.6	1.0	1.2	0.6	1.0	1.1	-0.4	0.3	0.3	0.6
Medication: Ventolin 100micrograms inhaler	0.5	0.6	3.6	0.1	0.5	0.1	0.2	0.8	0.3	0.6	1.9	0.9	-0.2
Forced vital capacity (FVC), Best measure	0.5	1.7	6.8	-1.4	-0.8	-2.6	-1.0	-0.9	-0.6	-1.6	-0.4	-0.6	-1.7
Alcohol intake frequency.	0.5	1.1	2.2	-1.1	-1.4	0.3	-1.1	-1.1	-1.5	-0.7	-0.4	-0.9	-1.2
Medication: Aspirin	0.5	0.6	3.6	0.5	0.1	1.9	-0.7	0.6	0.6	-0.2	-0.5	-0.0	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	2.4	1.0	1.2	0.3	0.4	1.6	1.5	0.3	1.3	0.9	1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.4	0.3	0.5	0.1	0.5	0.7	0.4	1.5	1.0	0.6	-0.3
Breast cancer (self-reported)	0.5	0.6	1.6	-0.7	-0.7	-1.0	-0.6	-0.8	-0.6	-1.3	-0.9	-0.1	0.1
Ever taken oral contraceptive pill	0.5	0.5	2.8	-0.4	0.7	-1.7	-0.5	0.5	0.8	-0.7	0.3	0.3	-0.4
Hearing aid user	0.5	0.6	1.5	-0.7	-0.2	-0.9	-0.8	-0.4	-0.3	0.2	-1.0	-1.1	-1.2
Average weekly beer plus cider intake	0.5	0.8	5.0	-0.1	0.1	1.2	-0.0	0.4	0.3	2.2	0.2	0.7	-0.8
Cholesterol lowering medication	0.5	0.7	2.1	1.1	0.6	1.5	0.3	0.8	0.9	0.3	0.4	0.5	1.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.4	-0.2	-0.7	1.5	-0.6	-1.0	-0.7	-0.0	-0.9	-0.5	-0.1
Alzheimer’s Disease (in father)	0.4	0.5	1.5	-0.0	0.9	-0.5	-0.1	1.2	0.9	0.0	1.2	0.0	-0.4
Irritable Bowel Disease (IBD)	0.4	0.9	2.7	0.7	0.4	1.1	0.5	0.5	0.1	1.6	0.7	1.3	1.3
Reaction Time	0.4	0.7	1.9	1.1	0.2	-0.6	1.3	0.1	-0.1	0.7	0.4	1.0	1.4
Coronary Artery Disease (CAD)	0.4	0.5	1.1	0.7	0.3	0.6	0.5	0.9	0.8	0.1	0.2	0.8	1.1
Primary Biliary Cirrhosis	0.4	0.5	1.1	-0.5	-1.0	-0.7	-0.8	-0.8	-0.8	0.2	-1.0	-0.2	-0.5
Smoking Status	0.4	0.9	3.1	-0.7	-0.3	1.3	-0.6	-0.4	-0.0	1.7	-0.1	-0.8	-1.8
Hand grip strength (left)	0.4	1.1	3.6	-1.3	-0.9	-0.5	-1.1	-1.2	-0.9	-0.7	-0.3	-0.6	-1.9
Medication for hormone replacement therapy	0.4	0.5	2.1	0.5	-0.6	-0.2	0.5	-0.6	-0.7	0.4	0.7	1.4	0.5
Diabetes (father)	0.4	0.4	1.6	-0.8	-0.3	-1.3	-0.5	-0.5	-0.5	0.3	0.2	-0.2	-1.0
Pack years adult smoking proportion	0.4	0.6	1.4	-0.7	-1.0	-0.6	-0.8	-1.2	-1.1	-0.9	-0.3	-0.4	-0.5
Maternal smoking around birth	0.4	0.6	3.4	0.5	0.8	1.8	0.5	0.6	0.8	0.2	0.2	0.0	0.5
Relative age voice broke	0.4	0.6	1.9	-1.1	-0.9	-0.2	-0.9	-0.8	-0.8	0.0	-0.5	0.1	-1.4
Diabetes (self-reported)	0.4	0.6	2.1	1.0	0.2	1.2	0.5	0.7	0.4	-0.0	0.3	0.4	1.5
Father’s age at death	0.4	0.6	1.9	0.2	0.7	-0.7	0.0	0.2	0.7	-1.4	-0.9	-1.3	0.1
Number of live births	0.4	0.6	1.9	0.4	1.4	0.5	0.7	1.1	1.1	-0.5	0.1	-0.3	0.4
Qualifications: A levels/AS levels or equivalent	0.4	0.9	5.2	-0.8	-0.5	-2.3	-0.7	-0.2	-0.4	-0.6	-0.6	-0.9	-0.9
Ever highly irritable/argumentative for 2 days	0.4	0.4	1.2	-0.7	-0.5	1.1	-0.6	-0.5	-0.6	-0.4	-0.1	-0.8	-0.7
Blood clot in the leg (DVT)	0.4	0.5	1.8	0.6	-0.1	0.4	1.1	-0.5	-0.5	-0.8	-0.9	0.0	1.3
Gout (self-reported)	0.4	0.5	1.7	-0.7	-0.1	0.3	-0.8	-0.1	0.1	0.9	-0.6	-0.9	-1.3
Hypothyroidism/myxoedema (self-reported)	0.4	0.9	1.8	-1.0	-0.9	0.6	-0.4	-1.4	-1.1	0.5	-0.9	-0.6	-1.3
Mean time to correctly identify matches	0.4	0.8	2.0	1.1	0.0	0.3	1.4	-0.2	-0.5	1.1	0.2	1.4	1.4
Heart disease (mother)	0.4	0.5	1.4	-0.6	-0.5	1.2	0.1	-0.7	-0.7	0.6	-1.0	-0.3	-0.7
Illnesses of siblings: Diabetes	0.4	0.5	1.8	0.2	0.1	-1.0	-0.0	0.1	-0.1	-1.4	0.3	1.0	0.9
Supplements: Fish oil (including cod liver oil)	0.4	0.6	3.8	0.6	0.5	1.9	0.7	-0.1	0.3	-0.2	-0.5	0.1	0.7
Ever depressed for a whole week	0.4	0.5	1.7	-0.3	0.4	1.2	0.0	-0.2	0.2	-1.3	-0.4	-0.9	-0.4
Arm predicted mass (left)	0.4	1.9	3.1	-1.4	-1.3	0.2	-1.2	-1.4	-1.4	-0.8	-1.7	-1.6	-1.8
Verbal and Numeric Reasoning (VNR)	0.3	0.7	4.8	-0.8	-0.4	-2.2	-0.3	-0.4	-0.6	-0.2	0.5	-0.1	-0.9
Leg fat-free mass (left)	0.3	1.3	3.3	-1.1	-1.0	-0.1	-1.1	-0.9	-1.1	-0.6	-1.4	-1.8	-1.5
Medication: Levothyroxine sodium	0.3	0.4	1.6	-0.3	-0.1	1.3	0.2	-0.7	-0.4	0.9	-0.6	-0.3	-0.8
Leg predicted mass (left)	0.3	1.4	3.5	-1.1	-1.0	-0.0	-1.1	-0.9	-1.1	-0.5	-1.4	-1.9	-1.6
Past tobacco smoking	0.3	0.6	3.1	-0.3	-0.0	-1.8	-0.1	-0.1	-0.2	-1.6	0.2	0.5	0.1
Nervous feelings	0.3	0.6	1.6	0.6	1.0	-0.3	0.7	0.7	0.8	-0.9	-0.3	-0.5	1.3
Financial difficulties in last 2 years	0.3	0.3	1.2	-0.6	-0.0	0.0	-0.8	0.5	0.5	-0.3	-0.5	-1.1	-0.5
Mouth/teeth dental problems	0.3	0.4	2.5	0.2	0.2	1.6	0.2	0.1	0.3	0.6	0.3	0.8	0.2
Heart attack	0.3	0.4	0.8	0.7	0.8	0.2	0.7	0.5	0.9	0.1	-0.7	0.2	0.9
Fluid intelligence score	0.3	0.7	6.1	-0.4	0.1	-2.5	-0.0	0.4	-0.0	-0.5	0.5	0.1	-0.1
Worrier / anxious feelings	0.3	0.5	1.0	0.5	0.8	0.8	0.6	0.7	0.9	1.0	-0.3	-0.5	0.7
Length of working week for main job	0.3	0.4	0.9	-0.7	-0.5	-0.9	-0.7	-0.2	-0.4	-0.3	-0.4	-1.0	-0.3
Breastfed as a baby	0.3	0.4	0.9	-0.2	-0.4	0.0	-0.2	-0.4	-0.5	0.9	0.9	0.9	-1.0
Hair/balding pattern: Pattern 4	0.3	0.8	2.3	-0.4	-1.1	1.1	-0.7	-0.9	-0.9	-1.5	-0.8	-0.6	-0.4
Comparative body size at age 10	0.3	0.8	2.0	-0.9	-0.6	0.2	-0.2	-1.2	-0.9	-0.3	-1.2	-0.8	-1.4
Age at first live birth	0.3	0.6	2.2	0.3	0.7	-1.3	0.3	0.9	0.8	1.5	0.1	0.3	0.2
Smoking status: Previous	0.3	0.4	1.5	-0.1	-0.5	1.2	-0.4	-0.1	-0.4	0.9	-0.6	-0.7	-0.1
Leg fat-free mass (right)	0.3	1.4	3.4	-1.2	-1.1	-0.4	-1.1	-0.9	-1.2	-0.8	-1.2	-1.8	-1.6
Handedness (chirality/laterality): Left-handed	0.3	0.3	2.2	0.3	0.2	0.7	-0.2	0.2	0.2	-1.5	-0.0	-0.2	0.3
Friendships satisfaction	0.3	0.3	1.0	-0.1	-0.1	-0.9	0.2	-0.2	-0.3	-0.9	0.7	1.0	0.1
Mineral and other dietary supplements	0.3	0.3	0.9	-0.8	-0.3	-0.8	-1.0	-0.1	0.0	-0.4	-0.3	-0.5	-0.8
Osteoarthritis (self-reported)	0.3	0.4	1.5	-0.6	-0.6	-0.2	-0.4	-0.6	-0.3	-1.2	-0.6	-0.3	-0.5
Leg predicted mass (right)	0.3	1.5	3.4	-1.2	-1.1	-0.3	-1.2	-0.9	-1.1	-0.8	-1.2	-1.8	-1.7
Financial situation satisfaction	0.3	0.3	0.8	-0.5	-0.6	0.5	-0.7	-0.4	-0.4	-0.6	-0.7	-0.9	-0.2
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.3	-0.9	-0.1	0.3	-1.1	0.0	0.2	-0.3	-0.3	-0.6	-1.0
Ever smoked	0.3	0.5	2.4	0.4	0.2	1.5	0.3	0.2	0.4	1.5	0.3	-0.1	-0.3
Basal metabolic rate	0.3	1.9	3.8	-1.3	-1.2	-0.1	-1.2	-1.2	-1.3	-0.9	-1.8	-1.9	-1.6
Arm fat-free mass (left)	0.3	1.5	2.7	-1.3	-1.1	0.4	-1.1	-1.2	-1.3	-0.7	-1.6	-1.6	-1.6
Unable to work because of sickness or disability	0.3	0.4	1.0	0.6	0.7	0.6	0.5	1.0	0.9	0.5	0.9	-0.0	0.4
Commuting to job workplace: Cycle	0.3	0.4	1.2	0.4	0.9	-0.6	0.5	0.0	0.7	-1.1	-0.1	0.0	0.7
Pain experienced in last month	0.3	0.5	0.9	0.5	0.5	0.6	0.7	0.8	0.7	0.3	1.0	0.9	0.5
Supplements: Calcium	0.3	0.3	1.0	0.5	0.1	1.0	0.4	0.1	0.2	0.3	0.9	0.8	0.2
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.8	0.8	0.8	0.3	0.8	0.5	0.8	0.4	-0.6	0.4	0.9
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.7	0.7	0.0	0.2	1.1	-0.3	-0.3	-0.6	-0.6	0.1	1.3
Depressed Affect (Nagel 2018)	0.2	0.5	1.6	-1.0	0.3	0.1	-0.4	-0.3	0.1	-1.0	-0.9	-1.3	-0.7
Depression (Nagel 2018)	0.2	0.4	1.2	-0.9	-0.0	0.1	-0.3	-0.9	-0.4	-0.5	-0.4	-0.2	-1.1
Schizophrenia (2018)	0.2	0.4	1.8	-0.1	-0.2	-1.0	-0.4	0.7	-0.1	0.5	1.4	0.5	-0.2
HDL Cholesterol	0.2	0.4	1.4	-0.3	-0.5	-0.9	-0.0	-0.5	-0.8	-0.3	-0.4	-1.2	-0.5
LDL Cholesterol	0.2	0.3	1.2	0.1	0.8	1.1	0.5	0.1	0.6	0.2	-0.6	0.2	0.1
Schizophrenia (2014)	0.2	0.3	1.0	0.2	0.5	-0.7	0.1	1.0	0.5	0.4	0.9	0.5	0.3
Triglycerides	0.2	0.3	0.5	-0.5	-0.5	0.3	-0.7	-0.7	-0.6	-0.7	-0.4	-0.3	0.0
Neuroticism	0.2	0.4	0.8	-0.7	-0.4	-0.1	-0.9	-0.5	-0.2	-0.8	-0.8	-0.9	-0.2
Tanning	0.2	3.0	8.0	2.3	1.2	0.8	1.3	2.4	1.8	1.4	1.2	0.9	2.8
Hearing difficulty/problems: Yes	0.2	0.3	1.4	-0.3	-0.6	0.1	-0.0	-1.2	-0.9	-0.3	0.2	0.6	-0.4
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.0	0.5	0.2	0.1	0.3	-0.0	0.3	0.3	0.2	1.0	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.1	-0.6	-0.2	0.6	-0.2	-0.8	-0.4	0.1	-0.1	0.2	-1.0
Age when periods started (menarche)	0.2	0.5	1.9	0.4	0.5	-0.5	0.1	0.7	0.5	1.0	1.4	0.8	-0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.6	0.0	-0.4	0.5	0.2	-0.3	-0.4	0.7	0.5	0.5	-0.2
Neuroticism score	0.2	0.5	0.9	-0.9	-0.4	-0.1	-0.5	-0.7	-0.4	-0.6	-0.8	-1.0	-0.9
Impedance of arm (right)	0.2	0.9	4.8	-0.5	-0.5	-1.4	-0.5	-0.6	-0.5	-2.2	-0.6	-0.6	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.0	0.6	0.7	0.3	1.0	0.4	0.5	1.0	0.2	-0.2	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.7	0.2	-0.8	0.8	-0.2	-0.3	-0.6	-0.2	-0.2	-0.2	0.5
Depression (self-reported)	0.2	0.2	0.5	0.6	0.5	-0.3	0.7	0.2	0.6	0.1	0.7	0.4	0.3
Tense / ‘highly strung’	0.2	0.3	0.9	0.0	0.6	-0.6	0.3	0.2	0.4	-0.9	-0.2	-0.9	0.1
Peak expiratory flow (PEF)	0.2	0.5	1.8	-1.1	-0.5	-0.3	-0.7	-0.7	-0.4	-0.6	-0.4	-0.4	-1.4
Headache pain in last month	0.2	0.3	1.0	-0.2	-0.3	-1.0	0.1	-0.8	-0.7	0.1	-0.8	-0.5	-0.1
Birth weight	0.2	0.5	1.8	-0.1	-0.3	0.9	0.4	-0.9	-0.5	-0.4	-1.3	-1.1	-0.2
Worry too long after embarrassment	0.2	0.4	1.0	-0.6	-1.0	-0.4	-0.6	-0.9	-0.8	0.4	-0.3	-0.1	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.0	0.1	0.4	0.1	0.1	0.1	0.3	-1.0	-0.1	0.6	0.5
Health satisfaction	0.2	0.3	0.5	-0.6	-0.4	0.5	-0.5	-0.4	-0.6	-0.7	-0.4	-0.7	-0.5
Qualifications: College or University degree	0.2	0.5	2.8	-0.6	-0.2	-0.9	-0.6	-0.3	0.0	-1.7	-0.5	-0.2	-0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.6	0.7	-0.1	-0.2	0.4	-0.2	-0.4	0.8	0.6	0.7	0.4
Medication: Allopurinol	0.2	0.3	0.5	-0.0	0.6	0.7	-0.1	0.5	0.7	0.2	-0.6	-0.7	-0.3
Number of full sisters	0.2	0.3	1.9	0.4	-0.0	1.4	-0.1	0.1	0.0	0.3	0.4	-0.1	0.5
Overall health rating	0.2	0.5	2.0	-0.3	-0.4	1.0	-0.8	-0.1	-0.3	0.2	-0.7	-1.4	-0.3
Had major operations	0.2	0.3	1.0	0.3	-0.2	-1.0	-0.0	0.4	-0.2	-0.7	0.0	-0.1	1.0
Age at last live birth	0.2	0.3	0.7	0.0	0.6	-0.8	0.2	0.5	0.6	0.8	0.3	0.4	-0.2
Family relationship satisfaction	0.2	0.2	0.5	-0.2	-0.3	0.2	-0.4	-0.6	-0.2	-0.6	0.6	0.7	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.6	-0.5	-0.8	-0.8	-0.8	-0.4	-0.7	0.3	-0.0	-0.2	-0.3
Whole body fat-free mass	0.2	1.0	2.3	-1.0	-0.8	0.2	-1.0	-0.8	-0.8	-0.5	-1.4	-1.5	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	1.5	-0.3	0.1	0.1	0.0	-0.4	0.2	-0.2	-1.2	-0.9	-0.9
Illnesses of father: None of the above (group 1)	0.2	0.2	1.0	0.0	0.3	-0.8	0.1	-0.1	0.3	-0.1	0.2	-0.2	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	1.4	-0.7	-0.3	-1.2	-0.5	-0.4	-0.2	-0.6	-0.1	-0.3	-0.8
Whole body water mass	0.2	1.0	2.2	-1.0	-0.7	0.3	-1.0	-0.8	-0.8	-0.5	-1.4	-1.5	-1.4
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.2	-0.3	-0.1	-1.1	0.1	-0.3	-0.6	-0.9	-0.2	0.1	0.0
Eye problems/disorders: Glaucoma	0.2	0.2	1.8	-0.3	-0.1	1.3	-0.1	-0.3	-0.1	-0.5	0.0	0.2	-0.4
Irritability	0.2	0.3	0.9	-0.3	-0.7	0.3	-0.1	-0.7	-0.7	0.0	-1.0	-0.8	-0.5
Age started oral contraceptive pill	0.2	0.3	1.4	-0.3	-0.3	-0.3	-0.0	-0.4	-0.5	-1.2	-0.6	-0.6	-0.1
Intelligence (Savage-Jansen 2018)	0.1	0.2	1.0	-0.4	-0.4	-1.0	-0.0	-0.1	-0.5	-0.0	0.6	0.4	-0.5
Ulcerative Colitis (UC)	0.1	0.2	0.7	0.0	-0.2	0.2	-0.1	-0.2	-0.4	0.4	0.2	0.9	0.7
Major Depression (MDD)	0.1	0.1	0.4	0.2	0.4	0.7	0.4	-0.0	0.2	-0.2	0.5	0.2	0.1
Ulcerative Colitis	0.1	0.2	0.7	0.2	0.1	-0.3	0.4	-0.0	-0.2	0.4	-0.1	0.6	0.9
Blood Eosinophil Count	0.1	1.0	8.8	-0.3	-0.1	-0.1	-0.1	0.7	0.2	3.0	0.1	0.3	0.3
Blood White Count	0.1	0.9	1.8	-1.0	-1.2	0.0	-1.0	-0.9	-0.8	0.3	-1.3	-1.3	-0.8
Heel T-Score	0.1	0.4	1.2	0.5	-0.0	1.0	0.5	-0.3	-0.3	-0.4	0.3	1.1	1.1
Height	0.1	1.2	2.8	-1.4	-0.7	0.7	-1.2	-0.8	-0.6	-0.7	-1.7	-1.1	-1.5
Lung FEV1/FVC ratio	0.1	0.3	0.8	0.6	0.4	-0.4	-0.4	0.9	0.7	-0.3	0.4	-0.4	0.9
Vitamin and mineral supplements	0.1	0.2	0.8	0.1	0.4	-0.3	0.1	0.3	0.6	0.9	0.1	-0.4	-0.6
Impedance of leg (right)	0.1	0.6	1.9	0.8	0.7	-0.0	0.8	0.3	0.7	0.6	0.7	1.4	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.4	-0.1	-0.2	0.5	-0.3	-0.4	-0.3	0.2	-0.6	-0.2	0.2
Multivitamins +/- minerals	0.1	0.1	0.5	0.3	-0.3	-0.1	-0.2	0.0	-0.2	0.2	0.7	0.7	0.4
Impedance of leg (left)	0.1	0.3	1.3	0.4	0.1	-0.9	0.4	-0.1	-0.0	0.1	0.6	1.1	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.6	0.2	0.8	-0.4	0.5	0.3	0.6	-0.2	-0.1	-0.2	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.1	-0.3	-0.3	0.5	-0.3	-0.7	-0.4	0.2	-1.1	-0.6	-0.2
Pain all over the body in last month	0.1	0.1	0.4	-0.1	0.1	0.3	0.5	-0.0	-0.3	0.5	0.6	0.2	-0.4
Trunk fat-free mass	0.1	0.6	1.4	-0.7	-0.3	0.7	-0.7	-0.4	-0.3	-0.3	-1.2	-1.1	-1.0
Pulse rate	0.1	0.2	0.8	-0.5	-0.5	-0.9	-0.3	-0.2	-0.3	0.1	0.1	0.5	-0.5
Happiness	0.1	0.1	0.3	-0.4	-0.1	-0.1	0.0	-0.4	-0.3	0.5	-0.1	-0.0	-0.5
Impedance of arm (left)	0.1	0.4	1.7	-0.2	-0.1	-1.3	-0.1	-0.1	-0.1	-1.3	0.1	0.1	0.4
Trunk predicted mass	0.1	0.6	1.4	-0.7	-0.3	0.7	-0.7	-0.4	-0.3	-0.3	-1.2	-1.1	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.9	-0.4	0.3	0.0	-0.1	-0.2	0.4	-0.3	-0.5	-0.6	-1.0
Arm fat-free mass (right)	0.1	0.4	1.0	-0.5	-0.4	0.8	-0.4	-0.4	-0.6	0.5	-0.8	-0.7	-1.0
Exposure to tobacco smoke outside home	0.1	0.1	0.9	-0.2	-0.1	0.0	-0.4	-0.0	0.1	-0.2	-0.3	-0.9	-0.5
Shortness of breath walking on level ground	0.1	0.2	0.6	0.2	0.6	0.5	-0.2	0.4	0.7	0.3	0.1	-0.2	-0.2
Medication for pain relief, constipation, heartburn	0.1	0.3	1.1	-0.4	0.0	-1.0	0.2	-0.1	-0.0	-1.0	0.2	0.5	-0.2
Migraine (self-reported)	0.1	0.1	0.4	-0.1	-0.1	0.4	0.4	-0.3	-0.3	0.7	0.4	0.4	-0.0
Arm predicted mass (right)	0.1	0.4	1.3	-0.6	-0.4	0.7	-0.5	-0.4	-0.6	0.5	-0.7	-0.7	-1.1
Suffer from ‘nerves’	0.1	0.2	0.5	0.6	0.2	0.5	0.6	0.2	0.2	-0.3	0.4	0.7	0.6
Leg pain on walking	0.1	0.2	0.5	0.4	0.4	0.3	-0.1	0.6	0.7	0.3	-0.2	-0.5	0.0
Illnesses of father: Heart disease	0.1	0.2	1.2	0.3	0.0	0.7	0.0	0.0	-0.1	-0.1	-0.3	0.0	1.1
Mood swings	0.1	0.1	0.3	-0.5	0.5	-0.1	0.2	-0.2	0.2	-0.3	-0.5	-0.2	-0.6
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.4	-0.1	-0.1	0.5	-0.0	-0.3	-0.2	-0.4	-0.6	-0.3	-0.1
Impedance of whole body	0.1	0.3	1.4	0.1	-0.0	-1.2	0.2	-0.1	-0.1	-0.7	0.5	0.7	0.6
Neuroticism (Nagel 2018)	0.0	0.1	0.5	-0.1	0.3	0.3	0.1	0.0	0.4	0.3	-0.3	-0.7	-0.1
Ovarian Cancer	0.0	0.0	0.1	0.1	0.1	0.1	-0.3	-0.2	0.2	-0.3	0.1	0.2	-0.2
Hair Pigment	0.0	1.3	4.2	0.6	1.5	0.3	0.7	1.0	1.2	2.0	1.6	0.7	-0.3
Ever unenthusiastic/disinterested for a whole week	0.0	0.1	0.2	0.1	0.1	0.0	0.3	-0.0	0.1	-0.3	-0.3	-0.0	0.5
Standing height	0.0	0.2	0.6	0.0	0.4	-0.3	0.0	0.5	0.4	-0.3	0.7	0.8	-0.2
Pulse rate, automated reading	0.0	0.1	0.3	-0.2	-0.5	-0.2	-0.3	-0.5	-0.5	-0.2	-0.3	-0.2	-0.1
Comparative height size at age 10	0.0	0.1	0.8	0.2	0.1	0.0	-0.1	-0.1	0.1	-0.9	-0.6	-0.0	0.0

Hub : Genes

NPPA

Models

Trait associations