Best TWAS P=5.41e-10 · Best GWAS P=6.74e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | ZNF318 | 0.04 | 0.03 | lasso | 8 | 0.02 | 1.3e-08 | 6.2 | 6.2 | 5.4e-10 | 0.99 | 0.00 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CRIP3 | 0.08 | 0.08 | blup | 34 | 0.07 | 1.0e-04 | 5.5 | 5.3 | 9.3e-08 | 0.86 | 0.00 | 0.99 | FALSE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF318 | 0.05 | 0.06 | lasso | 3 | 0.05 | 1.1e-06 | 5.5 | -5.6 | 2.2e-08 | -0.83 | 0.07 | 0.92 | FALSE |
4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZNF318 | 0.04 | 0.02 | blup | 48 | 0.04 | 2.2e-03 | 5.4 | 5.4 | 6.2e-08 | 0.87 | 0.02 | 0.53 | FALSE |