TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Medication: Blood pressure
:
←
→
chr6:42,611,872-44,034,691
Best TWAS P=5.41e-10 · Best GWAS P=6.74e-10 conditioned to 1
42.6M
42.8M
43M
43.2M
43.4M
43.6M
43.8M
44M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
NTR
Blood
ZNF318
0.04
0.03
lasso
8
0.02
1.3e-08
6.2
6.2
5.4e-10
0.99
0.00
1.00
TRUE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
ZNF318
0.05
0.06
lasso
3
0.05
1.1e-06
5.5
-5.6
2.2e-08
-0.83
0.07
0.92
FALSE
4
The Cancer Genome Atlas
Soft Tissue Sarcoma
ZNF318
0.04
0.02
blup
48
0.04
2.2e-03
5.4
5.4
6.2e-08
0.87
0.02
0.53
FALSE
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
CRIP3
0.08
0.08
blup
34
0.07
1.0e-04
5.5
5.3
9.3e-08
0.86
0.00
0.99
FALSE