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chr7:6,502,367-7,988,091

Best TWAS P=9.42e-10 · Best GWAS P=1.03e-07 conditioned to 0.627

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C1GALT1	0.26	0.15	enet	20	0.23	1.1e-27	4.7	6.1	9.4e-10	0.82	0.01	0.99	TRUE
11	GTEx	Nerve Tibial	C1GALT1	0.44	0.28	lasso	12	0.40	2.0e-30	5.1	5.9	3.0e-09	0.80	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1GALT1	0.16	0.12	lasso	7	0.14	3.7e-08	4.6	5.9	3.2e-09	0.64	0.01	0.99	FALSE
10	GTEx	Lung	C1GALT1	0.18	0.13	lasso	3	0.15	1.1e-11	5.3	5.8	4.9e-09	0.89	0.00	1.00	FALSE
16	METSIM	Adipose	C1GALT1	0.22	0.16	lasso	9	0.23	5.1e-34	4.4	5.8	7.7e-09	0.81	0.08	0.91	FALSE
13	GTEx	Skin Sun Exposed Lower leg	C1GALT1	0.22	0.04	lasso	9	0.10	4.8e-09	4.6	5.8	8.9e-09	0.70	0.03	0.96	FALSE
8	GTEx	Esophagus Mucosa	C1GALT1	0.33	0.19	lasso	6	0.18	2.8e-12	5.2	5.7	1.2e-08	0.66	0.00	0.99	FALSE
15	GTEx	Thyroid	C1GALT1	0.30	0.27	lasso	3	0.31	3.9e-24	5.1	5.6	1.9e-08	0.82	0.01	0.99	FALSE
9	GTEx	Esophagus Muscularis	C1GALT1	0.36	0.16	lasso	8	0.27	1.9e-16	5.3	5.6	2.0e-08	0.85	0.01	0.99	FALSE
7	GTEx	Colon Transverse	C1GALT1	0.32	0.23	lasso	4	0.30	8.0e-15	4.3	5.6	2.4e-08	0.73	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	C1GALT1	0.20	0.14	enet	18	0.15	1.5e-12	5.1	5.5	3.1e-08	0.85	0.01	0.99	FALSE
12	GTEx	Pancreas	C1GALT1	0.44	0.11	enet	24	0.22	8.8e-10	5.1	5.5	4.7e-08	0.81	0.01	0.99	FALSE
6	GTEx	Cells Transformed fibroblasts	C1GALT1	0.12	0.03	lasso	3	0.05	1.0e-04	5.1	5.4	6.4e-08	0.73	0.02	0.93	FALSE
14	GTEx	Stomach	C1GALT1	0.24	0.07	enet	17	0.12	1.9e-06	4.1	5.4	7.1e-08	0.74	0.05	0.94	FALSE
3	GTEx	Artery Tibial	C1GALT1	0.19	0.06	lasso	5	0.09	3.3e-07	5.1	5.4	7.3e-08	0.77	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	C1GALT1	0.02	0.01	lasso	4	0.01	1.7e-02	4.7	5.3	8.9e-08	0.93	0.01	0.96	FALSE
17	YFS	Blood	C1GALT1	0.35	0.20	enet	45	0.32	4.3e-109	5.3	5.2	2.0e-07	0.81	0.00	1.00	FALSE
4	GTEx	Brain Caudate basal ganglia	C1GALT1	0.27	0.18	enet	8	0.20	2.4e-06	4.4	5.2	2.2e-07	0.61	0.07	0.84	FALSE
5	GTEx	Brain Cerebellum	C1GALT1	0.36	0.09	enet	28	0.14	5.0e-05	5.0	5.2	2.2e-07	0.60	0.01	0.98	FALSE
20	The Cancer Genome Atlas	Lung Adenocarcinoma	C1GALT1	0.08	0.03	blup	112	0.06	2.5e-07	-1.6	5.1	2.7e-07	0.66	0.21	0.75	FALSE