Best TWAS P=2.74e-14 · Best GWAS P=1.84e-14 conditioned to 0.0235
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HOXA10 | 0.02 | 0.01 | blup | 53 | 0.01 | 0.00903 | -7.6 | 7.6 | 2.7e-14 | -0.85 | 0.00 | 0.84 | TRUE |
2 | The Cancer Genome Atlas | Esophageal Carcinoma | EVX1 | 0.16 | 0.02 | blup | 50 | 0.12 | 0.00014 | -0.1 | -6.5 | 6.8e-11 | 0.74 | 0.01 | 0.41 | FALSE |