Best TWAS P=1.9e-08 · Best GWAS P=1.04e-06 conditioned to 0.869
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | FES | 0.28 | 0.17 | enet | 21 | 0.20 | 2.8e-15 | 4.9 | -5.3 | 1.2e-07 | -0.92 | 0 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FES | 0.06 | 0.05 | blup | 46 | 0.07 | 7.4e-14 | 4.9 | -5.6 | 1.9e-08 | -0.88 | 0 | 0.98 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FES | 0.12 | 0.09 | lasso | 5 | 0.08 | 4.1e-09 | 4.9 | -5.2 | 2.5e-07 | -0.95 | 0 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | FES | 0.04 | 0.01 | blup | 46 | 0.02 | 1.7e-02 | 4.5 | -5.3 | 1.4e-07 | -0.75 | 0 | 0.27 | FALSE |