Best TWAS P=4.12e-09 · Best GWAS P=5.87e-10 conditioned to 0.00508
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | UFL1 | 0.08 | 0.05 | lasso | 4 | 0.04 | 7.9e-04 | -5.4 | -5.5 | 4.8e-08 | 0.71 | 0.11 | 0.83 | FALSE |
| 2 | GTEx | Nerve Tibial | UFL1 | 0.09 | 0.11 | lasso | 8 | 0.08 | 2.8e-06 | -5.4 | -5.4 | 8.3e-08 | 0.68 | 0.21 | 0.79 | FALSE |
| 3 | GTEx | Pancreas | UFL1 | 0.08 | 0.11 | enet | 7 | 0.09 | 1.1e-04 | -5.3 | -5.4 | 5.1e-08 | 0.71 | 0.13 | 0.71 | FALSE |
| 4 | NTR | Blood | KIAA0776 | 0.02 | 0.02 | lasso | 1 | 0.02 | 1.1e-07 | -5.6 | -5.6 | 2.0e-08 | 0.90 | 0.10 | 0.90 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | FHL5 | 0.04 | 0.03 | bslmm | 444 | 0.02 | 2.9e-03 | -5.3 | 5.3 | 1.3e-07 | -0.50 | 0.22 | 0.68 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | FHL5 | 0.03 | 0.02 | blup | 55 | 0.01 | 7.1e-03 | -5.4 | 5.9 | 4.1e-09 | -0.73 | 0.03 | 0.64 | TRUE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | KIAA0776 | 0.05 | 0.07 | lasso | 2 | 0.06 | 1.8e-06 | -5.5 | -5.6 | 2.2e-08 | 0.74 | 0.01 | 0.99 | FALSE |