[Hub]/) : Traits : Headache pain in last month :

chr1:149,672,809-151,227,371

Best TWAS P=1.41e-11 · Best GWAS P=6.89e-11 conditioned to 0.506

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ADAMTSL4 0.17 0.14 lasso 4 0.10 3.7e-06 6.5 -6.5 8.2e-11 -0.94 0.00 1.00 FALSE
2 GTEx Artery Aorta RP11-54A4.2 0.12 0.13 lasso 2 0.11 7.7e-07 6.5 -6.5 9.8e-11 -0.95 0.00 1.00 FALSE
3 GTEx Artery Tibial ADAMTSL4 0.10 0.06 lasso 4 0.08 6.4e-07 6.5 -6.5 9.5e-11 -0.93 0.00 1.00 FALSE
4 GTEx Artery Tibial RP11-54A4.2 0.10 0.07 lasso 4 0.09 1.3e-07 6.5 -6.3 3.8e-10 -0.90 0.00 1.00 FALSE
5 GTEx Cells Transformed fibroblasts ADAMTSL4 0.08 0.01 lasso 4 0.01 2.6e-02 6.5 -6.4 1.8e-10 -0.91 0.01 0.98 FALSE
6 GTEx Cells Transformed fibroblasts RP11-54A4.2 0.08 0.01 lasso 8 0.02 1.8e-02 5.5 -5.8 6.2e-09 -0.79 0.03 0.95 FALSE
7 GTEx Esophagus Mucosa ECM1 0.14 0.10 lasso 10 0.12 2.2e-08 6.5 -6.8 1.4e-11 -0.93 0.00 1.00 TRUE
8 GTEx Esophagus Mucosa ADAMTSL4 0.40 0.40 lasso 5 0.41 5.8e-29 6.5 -6.7 2.6e-11 -0.97 0.00 1.00 FALSE
9 GTEx Esophagus Mucosa RP11-54A4.2 0.35 0.33 enet 15 0.34 1.6e-23 6.5 -6.7 2.7e-11 -0.96 0.00 1.00 FALSE
10 GTEx Muscle Skeletal TARS2 0.11 0.09 lasso 1 0.07 8.5e-08 5.5 5.5 4.3e-08 0.69 0.44 0.56 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic MRPS21 0.09 0.06 lasso 3 0.06 2.6e-04 6.5 -6.5 7.0e-11 -0.91 0.01 0.97 FALSE
12 GTEx Thyroid MRPS21 0.21 0.22 lasso 7 0.24 2.2e-18 5.5 -5.4 7.7e-08 -0.69 0.52 0.48 FALSE
13 METSIM Adipose MRPS21 0.06 0.07 lasso 7 0.06 5.1e-10 5.4 -5.3 1.0e-07 -0.68 0.53 0.47 FALSE
14 The Cancer Genome Atlas Bladder Urothelial Carcinoma C1orf54 0.06 0.02 blup 17 0.03 2.5e-03 -4.7 5.2 1.6e-07 0.54 0.00 0.82 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ADAMTSL4 0.11 0.07 lasso 4 0.07 1.2e-08 6.5 -6.4 1.6e-10 -0.93 0.00 1.00 FALSE
16 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ECM1 0.04 0.04 blup 26 0.04 4.9e-05 6.5 -6.0 1.7e-09 -0.83 0.00 1.00 FALSE
17 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ADAMTSL4 0.12 0.09 lasso 5 0.09 6.0e-06 6.5 -6.1 1.1e-09 -0.90 0.00 1.00 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma ADAMTSL4 0.07 0.05 blup 33 0.05 5.6e-06 6.5 -5.8 5.6e-09 -0.79 0.00 1.00 FALSE