Hub : Genes

ECM1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.2680	0.1030	7.8e-03	0.089	NA	0.021	NA	0.041	2.8e-03	NA	9.6e-02	NA	3.2e-02
2	GTEx	Brain Cerebellum	0.3390	0.1000	2.2e-04	0.207	NA	0.039	NA	0.188	9.0e-07	NA	2.6e-02	NA	3.2e-06
3	GTEx	Brain Putamen basal ganglia	0.3760	0.1260	2.8e-03	-0.010	NA	-0.009	NA	-0.005	6.8e-01	NA	6.0e-01	NA	4.4e-01
4	GTEx	Cells Transformed fibroblasts	0.4040	0.0900	3.9e-10	0.150	NA	0.181	NA	0.200	2.4e-11	NA	1.6e-13	NA	6.1e-15
5	GTEx	Esophagus Mucosa	0.1380	0.0490	7.6e-06	0.101	NA	0.109	NA	0.120	3.1e-07	NA	9.9e-08	NA	2.2e-08
6	GTEx	Stomach	0.1530	0.0740	7.1e-03	0.034	NA	0.012	NA	0.024	9.2e-03	NA	8.1e-02	NA	2.6e-02
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0450	0.0244	9.2e-05	0.036	0.037	0.035	NA	0.037	5.6e-05	4.9e-05	8.1e-05	NA	4.9e-05
8	TCGA	Brain Lower Grade Glioma	0.0748	0.0374	7.4e-05	0.028	0.048	0.050	NA	0.051	3.6e-04	3.5e-06	2.4e-06	NA	1.6e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	3.0	4.7	9.4	-2.5	-2.3	-3.1	-1.8	-0.7	2.7	-0.2	-2.5
Bipolar Disorder or Schizophrenia	1.5	3.5	17.3	-1.3	-1.0	-2.6	-0.7	-0.5	4.2	0.4	-0.8
Depressed Affect (Nagel 2018)	0.1	0.3	0.8	-0.0	-0.0	-0.8	0.2	0.5	0.9	0.8	-0.3
Depression (Nagel 2018)	0.9	1.4	7.5	0.9	0.9	-1.0	0.8	-0.3	2.7	0.3	-0.0
Intelligence (Savage-Jansen 2018)	0.4	1.1	2.8	-1.7	-1.5	-0.1	-0.9	-0.1	-1.5	-0.7	0.4
Neuroticism (Nagel 2018)	0.4	0.9	3.6	0.4	0.5	-0.9	0.8	1.1	1.9	0.9	-0.1
Schizophrenia (2018)	0.8	1.6	10.2	0.4	0.6	-0.9	0.5	-0.1	3.2	0.7	0.9
Schizophrenia vs Biploar Disorder	1.6	2.1	5.1	1.6	1.5	2.3	1.5	0.7	-0.3	0.6	1.9
Worry (Nagel 2018)	0.3	0.6	2.3	0.3	0.4	-0.3	1.0	1.0	1.5	0.5	0.4
Alzheimer’s Disease (in mother)	0.9	1.0	4.1	1.3	1.4	0.5	0.4	0.1	-2.0	0.1	-0.5
Alzheimer’s Disease (in father)	0.7	0.7	1.7	-1.0	-0.9	-0.3	-1.3	0.1	-1.3	-0.7	-0.1
Alzheimer’s Disease (including proxy)	0.6	0.8	3.5	0.9	1.2	0.8	0.1	0.3	-1.9	-0.1	0.3
Crohns Disease (2017)	2.2	4.9	13.4	1.2	1.6	-1.8	2.6	3.7	0.3	3.4	-1.0
Irritable Bowel Disease (IBD)	3.9	9.3	22.1	0.6	1.0	-3.5	2.8	4.7	2.1	4.7	-2.3
Ulcerative Colitis (UC)	3.1	5.9	11.4	-0.5	-0.3	-3.3	1.3	3.1	2.7	3.4	-2.4
Major Depression (MDD)	0.3	0.3	0.7	-0.8	-0.7	-0.1	-0.8	-0.3	-0.5	-0.3	-0.6
Reaction Time	3.8	7.2	17.2	-3.0	-3.1	-4.2	-1.5	1.1	0.5	1.1	-4.1
Verbal and Numeric Reasoning (VNR)	0.4	0.9	1.9	-1.4	-1.2	-0.4	-1.0	-0.0	-1.3	-0.4	-0.6
Breast Cancer	0.4	1.1	3.2	-0.6	-0.6	0.1	-1.4	-1.2	1.8	-1.2	-0.1
Ovarian Cancer	0.5	0.7	1.4	0.5	0.8	0.8	-0.5	-1.2	-0.9	-1.0	-0.7
Prostate Cancer	0.9	1.3	3.0	-1.1	-1.1	-0.2	0.8	1.1	-1.7	0.9	-1.4
Age at First Birth	1.9	2.8	7.5	-1.5	-1.2	-1.0	-2.7	-1.4	-1.6	-2.1	-1.0
Bipolar Disorder (2011)	1.6	1.5	6.1	-0.3	0.1	-0.8	-1.1	-1.9	2.5	-0.9	0.0
Body Mass Index (BMI) (2010)	1.5	2.1	6.2	0.7	0.6	-0.6	1.8	2.5	-0.4	2.1	-1.2
Coronary Artery Disease (CAD)	2.0	2.4	4.7	1.5	1.8	0.0	2.0	2.2	-0.4	2.0	-0.7
Crohns Disease (2012)	1.8	2.9	7.8	0.9	1.1	-1.1	2.0	2.8	-0.5	2.7	-0.8
Mean Putamen Volume	2.6	3.0	5.4	2.1	2.1	0.1	2.3	1.9	0.8	2.3	0.2
Fasting Glucose	0.9	1.1	2.2	0.1	0.2	1.4	-0.6	-1.5	-0.0	-1.5	1.4
HbA1C	1.3	1.4	3.8	1.0	1.2	1.8	0.3	-0.7	0.4	-1.0	1.9
HDL Cholesterol	0.1	0.2	0.8	0.1	-0.2	0.6	-0.1	-0.9	-0.0	-0.6	-0.0
LDL Cholesterol	1.2	1.9	3.4	-0.6	-0.4	1.8	-1.3	-1.3	-1.9	-1.5	1.6
Lupus	1.0	1.6	7.3	-0.9	-0.7	-0.8	-1.1	-0.6	2.7	-1.4	0.3
Neuroticism (2016)	0.4	0.6	2.3	0.2	0.7	-0.9	0.3	0.4	0.7	0.3	1.5
Primary Biliary Cirrhosis	0.4	0.6	2.2	0.2	0.3	-1.2	0.3	0.4	1.5	0.6	0.2
Rheumatoid Arthritis	1.7	2.4	7.6	2.8	2.6	1.6	1.2	-0.2	0.7	-0.2	0.4
Schizophrenia (2014)	1.2	2.6	13.4	-1.3	-1.0	-1.7	-1.0	-0.9	3.7	-0.3	-0.2
Triglycerides	0.2	0.3	0.7	-0.6	-0.8	-0.0	-0.4	-0.6	0.4	-0.6	-0.8
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.8	0.3	0.3	-0.7	1.1	1.4	0.7	1.1	0.3
Ulcerative Colitis	3.8	5.5	12.5	-0.2	0.0	-2.9	1.6	2.8	3.3	3.5	-1.4
Blood Eosinophil Count	1.2	9.0	18.7	3.1	1.9	-4.0	2.6	4.3	-1.0	3.9	-0.4
Blood Platelet Count	2.4	27.3	48.7	-5.3	-6.2	-7.0	-2.8	1.6	6.3	2.5	-6.9
Blood Red Count	0.2	2.4	13.2	-0.6	-0.8	0.6	-0.2	1.2	-3.6	0.4	-1.7
Blood White Count	2.1	15.8	43.8	3.5	2.7	-2.6	4.7	6.6	-0.9	5.7	-0.7
Heel T-Score	0.4	3.4	11.8	-0.3	-0.1	0.2	-2.2	-3.4	1.8	-2.7	-0.1
BMI	1.6	9.3	23.4	4.8	4.7	2.1	3.6	1.8	0.1	2.6	1.2
Height	0.3	6.6	17.9	2.2	1.5	-0.9	3.8	4.2	1.6	3.2	-0.6
Waist Hip Ratio (WHR)	1.5	6.5	12.9	-3.3	-2.9	-3.6	-0.2	2.8	1.3	2.1	-2.6
Systolic Blood Pressure	0.3	1.5	3.1	-1.4	-1.2	-1.2	0.8	1.8	0.1	1.7	0.5
Smoking Status	0.4	0.9	2.0	1.4	1.3	0.9	0.2	-0.7	-0.5	-0.9	1.1
Allergy or Eczema	3.3	8.8	17.6	-3.6	-3.4	-0.5	-4.2	-2.3	-3.0	-3.7	-0.4
Cardiovascular Disease	0.4	1.3	2.6	1.4	1.6	1.5	0.7	-0.5	1.4	-0.2	1.2
Hypothyroidism (self reported)	1.2	2.9	9.7	1.6	1.7	-0.4	1.8	0.9	3.1	1.7	-0.5
Respiratory disease	2.7	6.0	16.9	-0.9	-0.5	2.0	-2.6	-3.1	-3.0	-4.1	1.3
Type 2 Diabetes (T2D) (2018)	1.1	2.1	5.3	2.0	2.3	1.7	1.0	-0.6	0.6	-0.9	1.5
Lung FEV1/FVC ratio	1.3	6.6	14.9	0.1	0.5	2.9	-2.9	-3.6	-2.6	-3.9	1.2
Lung FVC	2.1	10.6	37.7	0.6	0.9	3.0	-1.3	-6.1	3.6	-3.8	2.9
Neuroticism	0.8	2.0	5.3	1.4	1.6	-0.2	1.7	1.2	2.3	1.2	0.6
Chronotype (morning person)	10.9	25.1	52.2	-1.2	-1.7	-6.4	2.8	7.1	4.5	7.2	-5.0
Hair Pigment	0.3	7.1	13.9	0.4	-0.0	3.5	-2.1	-2.6	-3.7	-3.2	3.0
Tanning	0.7	9.0	24.5	-1.6	-2.2	-0.2	-4.2	-4.3	-1.8	-5.0	0.3
Hand grip strength (left)	3.9	10.2	25.8	1.2	1.1	4.8	-1.9	-5.1	-0.3	-4.7	2.2
Number of treatments/medications taken	2.5	4.4	13.8	0.0	0.4	1.7	-2.2	-3.3	-0.4	-3.7	1.7
Average weekly spirits intake	1.6	2.0	4.5	2.1	1.7	1.9	0.1	-1.4	-0.1	-0.9	1.6
Sensitivity / hurt feelings	2.3	3.9	10.7	0.6	0.7	-1.5	1.8	2.1	3.3	2.7	-1.6
Frequency of depressed mood in last 2 weeks	1.0	1.4	9.1	0.7	0.6	-0.6	0.5	-0.5	3.0	0.1	0.7
Hearing difficulty/problems: Yes	1.7	2.5	8.9	0.0	0.0	1.8	0.2	-1.2	-3.0	-2.0	1.6
Relative age of first facial hair	0.6	1.1	2.5	-0.9	-1.3	0.1	-1.1	-0.4	-1.4	-1.6	-0.8
Other serious medical condition/disability diagnosed by doctor	1.6	2.0	4.8	-2.1	-2.2	-1.5	-1.5	-0.2	0.1	-0.5	-1.4
Ever used hormone-replacement therapy (HRT)	1.1	1.4	3.0	-1.4	-1.4	-0.3	-1.6	-0.7	-0.4	-1.0	-1.7
Ever had hysterectomy (womb removed)	0.5	0.6	1.2	-0.7	-1.1	0.4	-0.7	-1.0	0.3	-0.9	0.3
Systolic blood pressure, automated reading	0.2	0.7	1.4	-0.1	-0.0	-0.3	1.1	1.1	-0.3	1.2	1.0
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	0.3	0.5	0.3	-0.5	-0.3	-0.3	-0.0	-0.0
Angina	0.8	1.1	3.4	0.3	0.8	-0.8	1.1	1.8	-0.1	1.4	-0.8
Medication for hormone replacement therapy	1.7	1.9	4.3	-2.1	-1.8	-0.3	-1.9	-1.5	0.1	-1.2	-0.2
Vitamin and mineral supplements	0.9	1.2	4.0	-1.0	-0.9	0.3	-1.2	-0.1	-2.0	-0.9	1.1
Supplements: Zinc	1.8	2.0	5.1	1.5	1.8	1.5	0.6	-1.2	2.3	-0.5	1.0
Medication: Co-codamol	1.6	1.8	3.1	-1.7	-1.7	0.9	-1.2	-0.4	-1.8	-1.5	-1.1
Medication: Metformin	3.9	5.5	11.6	3.4	3.4	3.1	2.1	-0.4	1.4	-0.4	2.2
Diabetes (father)	0.6	0.7	1.6	0.9	1.0	0.8	0.6	0.3	0.9	0.7	1.3
Diabetes (mother)	2.1	2.6	5.6	1.7	1.8	2.4	0.9	-1.7	1.1	-1.4	1.6
Severe depression (siblings)	1.0	1.2	2.6	-1.4	-1.4	-1.6	-0.3	0.8	1.1	0.3	-0.9
Pack years adult smoking proportion	0.7	1.1	5.1	0.9	0.7	0.3	0.7	0.7	-2.3	0.2	0.9
Impedance of leg (right)	0.8	3.9	21.3	-0.7	-0.0	2.5	0.4	0.7	-4.6	-1.4	0.9
Leg fat-free mass (left)	1.2	6.5	18.8	4.3	3.8	1.2	3.0	1.1	1.8	1.8	0.7
Trunk fat percentage	2.9	11.5	26.5	4.7	5.1	3.8	3.9	1.7	-2.8	1.2	1.0
Hand grip strength (right)	3.9	10.6	28.4	0.5	0.3	4.4	-2.7	-5.3	-1.1	-5.0	1.8
Townsend deprivation index at recruitment	0.5	0.8	1.5	1.0	1.1	0.8	0.4	0.2	-1.2	-0.5	1.1
Current tobacco smoking	0.9	1.5	3.3	1.7	1.8	1.7	0.8	-0.3	-0.5	-0.6	1.2
Average weekly fortified wine intake	0.3	0.4	0.9	0.7	0.5	0.6	0.4	-0.4	0.7	-0.9	0.4
Maternal smoking around birth	0.1	0.1	0.5	-0.1	-0.3	-0.1	0.0	0.4	-0.3	-0.2	0.7
Fed-up feelings	0.1	0.1	0.2	-0.4	-0.4	-0.4	-0.4	-0.1	0.3	-0.2	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	2.7	1.6	1.6	-0.3	1.3	1.0	1.2	1.1	0.2
Relative age voice broke	0.5	0.7	3.2	-0.6	-0.9	0.3	0.1	0.8	-1.8	0.0	-0.8
Taking other prescription medications	1.1	1.6	5.0	0.4	0.6	1.5	-0.6	-1.5	-0.1	-2.2	1.6
Age when periods started (menarche)	1.2	2.8	6.0	-0.5	-1.2	-2.0	1.0	2.4	1.5	2.1	-1.8
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.4	-0.7	-0.9	0.5	-0.9	-0.7	0.7	-0.8	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.2	-0.1	-0.1	0.7	-0.4	-1.0	0.7	-1.1	-0.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	-0.8	-0.9	-0.6	-1.1	-0.4	0.1	-0.0	-0.7
Qualifications: CSEs or equivalent	3.6	4.7	10.3	2.9	3.2	2.0	2.7	1.9	-0.5	1.8	1.1
Serious illness, injury or assault to yourself	0.9	1.1	4.0	0.5	0.2	2.0	-0.2	-0.6	-0.3	-1.2	1.5
High blood pressure	0.2	0.5	3.2	0.5	0.6	-0.3	-0.0	-0.4	1.8	-0.1	0.5
Hayfever, allergic rhinitis or eczema	2.5	5.4	11.4	-2.8	-2.5	-0.1	-3.4	-2.0	-1.8	-3.3	-0.2
Multivitamins +/- minerals	1.3	1.7	2.7	1.2	1.0	-0.5	1.6	1.2	1.5	1.3	-1.6
Stomach or abdominal pain in last month	3.1	3.9	7.1	2.4	2.7	1.4	2.2	-0.0	2.4	1.3	2.0
Supplements: Glucosamine	3.2	4.2	10.0	0.4	0.5	2.6	-1.3	-2.6	-2.4	-3.2	1.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.3	1.1	1.2	0.4	0.5	-0.4	0.9	0.3	-0.2
Medication: Atenolol	1.4	1.8	5.4	-1.0	-1.0	-1.3	0.4	1.9	0.4	2.3	-1.0
Medication: Levothyroxine sodium	1.8	3.1	8.7	1.4	1.5	-0.8	1.7	1.2	3.0	1.8	-1.9
Sitting height	0.7	5.3	17.7	-0.2	-0.7	-1.6	2.8	4.2	-0.8	3.1	-1.8
Chronic bronchitis/emphysema (father)	2.1	2.4	5.5	-1.9	-1.9	-2.2	-1.3	0.5	-0.1	-0.5	-2.3
High blood pressure (mother)	0.5	0.6	2.0	-0.0	-0.1	-0.5	0.7	0.8	1.4	1.4	0.3
Body mass index (BMI)	1.5	6.4	17.6	4.1	4.2	2.3	2.5	0.6	-0.5	1.5	1.4
Impedance of leg (left)	0.8	3.9	22.1	-1.8	-1.1	1.3	-0.3	0.7	-4.7	-1.4	-0.4
Leg predicted mass (left)	1.3	6.7	19.2	4.4	3.9	1.3	3.0	1.1	1.8	1.7	0.8
Trunk fat mass	2.7	11.6	27.6	5.0	5.3	3.4	4.1	1.9	-1.9	1.7	1.1
Waist circumference	1.5	5.5	12.2	3.1	3.5	1.6	3.0	1.9	-1.3	1.9	1.2
Number of incorrect matches in round	1.7	2.8	7.0	-0.1	-0.3	-2.4	0.9	1.5	2.1	2.6	-1.4
Past tobacco smoking	0.1	0.2	0.9	-0.2	-0.1	-0.2	-0.3	0.4	0.5	0.3	-0.9
Alcohol usually taken with meals	4.2	6.7	12.4	-3.3	-3.5	-1.4	-3.4	-2.8	0.6	-3.0	0.1
Nervous feelings	0.3	0.6	1.7	-0.5	-0.5	-0.7	0.8	1.3	1.1	0.5	0.5
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.6	5.2	-0.2	-0.4	-2.3	-0.3	0.7	2.2	0.5	-1.5
Hearing difficulty/problems with background noise	2.3	3.7	8.2	1.6	1.5	2.5	1.4	-0.9	-2.3	-1.2	2.9
Hair/balding pattern: Pattern 2	2.5	3.2	7.7	1.3	1.2	-0.4	2.3	2.7	1.1	2.8	-0.3
Had menopause	0.3	0.4	2.2	0.1	-0.5	0.0	0.1	-0.3	1.5	0.2	-0.6
Had other major operations	1.6	1.9	4.8	0.8	0.8	1.9	-0.3	-1.5	-0.9	-1.5	2.2
Forced vital capacity (FVC)	1.1	4.1	11.5	0.8	0.9	2.3	0.0	-3.4	2.7	-2.3	1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	1.8	1.1	1.1	0.7	0.1	-0.9	1.3	-0.8	0.8
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	4.2	-2.0	-1.8	-0.6	-2.0	-1.4	-1.0	-1.9	-0.9
Qualifications: None of the above	0.3	0.7	1.4	0.3	0.2	1.0	-0.6	-1.2	-1.2	-0.8	0.7
Financial difficulties in last 2 years	1.2	1.6	3.2	1.6	1.3	1.8	0.9	-0.6	-0.9	0.2	1.8
Mouth/teeth dental problems	0.2	0.2	1.5	-0.2	-0.2	0.3	-0.1	-0.2	-1.2	-0.4	0.1
Heart attack	1.0	1.3	2.5	-1.6	-1.3	-1.6	-0.3	1.0	0.4	0.8	-1.5
Allergy	1.9	4.3	13.0	1.6	1.3	-0.9	2.7	2.4	1.7	3.6	-0.8
Pain all over the body in last month	0.8	0.9	2.4	-0.2	-0.2	0.5	-1.1	-0.6	-1.2	-1.1	1.6
Diabetes (self-reported)	1.8	2.8	7.2	2.5	2.7	1.2	1.6	0.8	-0.2	0.1	2.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.0	-0.8	-0.7	-0.4	-0.6	-0.2	-1.0	-0.6	-0.2
Medication: Ramipril	0.4	0.6	1.8	-0.3	0.0	-0.4	-1.3	-1.0	-0.3	-1.2	0.1
Medication: Simvastatin	0.1	0.1	0.3	-0.3	-0.2	-0.0	-0.5	-0.1	-0.1	-0.5	0.4
Fluid intelligence score	0.4	0.9	1.9	-1.4	-1.2	-1.3	-0.7	0.3	-0.5	0.5	-1.1
Illnesses of siblings	0.7	0.9	1.5	-1.2	-1.2	-1.1	-1.0	0.6	-1.2	0.5	0.5
Neuroticism score	1.5	3.1	8.1	0.2	0.4	-1.4	2.0	2.8	2.1	2.5	-0.0
Weight	1.8	8.6	21.8	4.7	4.5	2.3	3.6	1.7	-0.6	2.0	1.1
Impedance of arm (right)	0.4	2.0	4.3	0.6	1.3	1.7	2.0	2.1	-1.8	0.0	0.2
Arm fat percentage (right)	3.2	12.6	31.3	5.2	5.6	3.4	4.1	2.1	-2.0	2.1	1.7
Trunk fat-free mass	0.7	4.0	8.8	3.0	2.3	-0.2	2.3	1.4	2.2	2.4	0.3
Hip circumference	3.3	14.1	32.7	5.5	5.7	4.3	3.8	1.1	-2.4	1.1	3.0
Time employed in main current job	0.3	0.3	0.7	0.0	-0.2	0.8	-0.5	-0.5	-0.7	-0.8	-0.4
Alcohol intake versus 10 years previously	0.4	0.6	1.1	0.5	0.8	-0.3	1.0	0.9	-0.5	0.8	-0.8
Father’s age at death	1.0	1.3	3.8	-1.9	-1.9	-0.8	-0.9	-0.8	-1.0	-0.6	-0.1
Worrier / anxious feelings	0.9	1.7	4.7	0.0	-0.0	-1.3	1.2	1.7	2.2	1.6	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.1	0.7	0.8	1.1	-0.0	-1.3	1.2	-1.2	1.4
Falls in the last year	0.2	0.2	0.9	0.1	-0.0	0.8	0.0	-0.3	-0.1	-0.6	0.9
Hair/balding pattern: Pattern 3	2.0	2.9	6.1	-1.9	-1.9	-0.2	-2.5	-2.4	-0.1	-2.1	-0.1
Number of live births	1.6	2.3	4.8	-0.8	-1.1	-2.2	0.6	1.6	1.8	1.5	-1.8
Forced expiratory volume in 1-second (FEV1)	1.6	5.3	14.9	1.2	1.3	3.3	-0.3	-3.9	1.7	-2.8	1.8
Pulse rate	1.9	3.2	10.7	-1.0	-0.8	0.3	-2.7	-2.4	-0.1	-3.3	-0.2
Happiness	0.8	0.9	2.9	-0.2	-0.5	-1.6	0.1	0.4	1.7	1.0	-0.7
Noisy workplace	1.8	2.3	5.9	1.2	1.3	0.1	1.9	1.8	1.3	2.4	-0.7
Qualifications: A levels/AS levels or equivalent	0.7	1.6	2.9	-1.0	-0.6	0.2	-1.5	-1.7	-1.6	-1.7	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.7	1.3	1.1	0.9	0.4	-0.5	-0.4	-0.2	0.3
Mouth/teeth dental problems: Dentures	0.8	1.3	6.2	-1.2	-1.0	-1.0	-0.5	0.5	0.3	0.5	-2.5
Asthma	2.0	4.0	9.7	0.9	1.4	2.5	-0.7	-2.1	-1.7	-3.1	2.3
Medication: Ibuprofen (e.g. Nurofen)	5.7	7.3	17.4	1.1	1.3	4.2	-0.9	-3.1	-1.9	-3.3	3.6
Medication: Cholesterol lowering	0.3	0.5	1.5	-0.2	0.1	-0.8	-0.1	0.9	-1.2	0.7	-0.2
Depression (self-reported)	1.0	1.2	3.5	-1.3	-0.7	-1.0	-1.3	-1.1	0.2	-1.9	-0.1
Medication: Lansoprazole	1.2	1.4	4.7	-1.0	-0.6	0.7	-1.4	-1.5	0.0	-2.2	-0.7
Prospective memory result	1.8	2.2	6.3	0.5	0.4	-1.2	1.5	2.2	0.5	2.5	-1.6
Lung cancer (father)	0.4	0.4	1.2	-0.7	-0.8	-0.1	-0.6	-0.2	-1.1	-0.3	-0.9
Illnesses of mother	1.6	2.0	5.0	-1.5	-1.7	-0.5	-2.2	-1.2	-0.4	-1.6	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.5	8.6	1.1	1.2	2.7	0.2	-2.9	1.7	-2.0	1.7
Pulse wave Arterial Stiffness index	1.4	1.6	3.5	1.0	1.2	1.9	0.2	-1.6	0.3	-1.8	1.1
Impedance of arm (left)	0.3	1.5	4.2	-0.2	0.4	1.9	1.3	1.3	-2.0	-1.0	-0.4
Arm fat mass (right)	3.0	12.3	30.3	5.4	5.5	3.1	4.2	1.9	-1.0	2.3	1.5
Trunk predicted mass	0.7	3.9	8.6	2.9	2.3	-0.2	2.3	1.4	2.2	2.3	0.2
Standing height	0.3	2.7	7.7	1.7	1.2	0.1	2.8	2.6	0.3	1.5	-0.8
Length of working week for main job	0.7	0.8	2.2	0.3	0.2	0.6	1.4	1.5	-0.5	1.1	0.4
Exposure to tobacco smoke at home	0.2	0.2	0.8	-0.3	-0.6	-0.9	-0.2	-0.4	0.2	-0.1	-0.3
Breastfed as a baby	1.8	2.2	6.8	-0.6	-0.4	0.8	-1.7	-2.5	-0.6	-2.6	0.1
Tense / ‘highly strung’	0.5	0.8	2.4	-0.5	-0.3	-1.5	0.3	1.2	1.3	0.3	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	4.7	-0.1	0.3	0.1	-0.8	-2.2	0.4	-1.9	1.0
Hair/balding pattern: Pattern 4	0.9	2.1	4.7	-1.3	-1.6	0.1	-2.2	-2.0	-0.5	-1.8	0.6
Birth weight of first child	0.7	1.4	7.4	0.9	0.6	-0.3	1.0	0.9	2.7	0.6	-0.0
Peak expiratory flow (PEF)	3.6	8.3	18.3	0.5	0.6	4.2	-1.6	-4.3	-1.6	-4.1	2.7
Pulse wave reflection index	1.8	2.2	4.8	1.6	1.3	2.2	0.5	-1.5	-0.0	-1.2	2.2
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.0	-0.5	-0.8	-0.2	-0.6	-0.8	1.4	-0.6	-1.1
Loud music exposure frequency	1.4	1.6	6.6	-0.0	0.0	1.0	-0.6	-2.0	-0.7	-2.6	-0.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.3	-0.3	0.0	-0.4	0.0	0.2	0.6	0.1	-0.0
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.4	0.9	0.8	-0.3	1.0	1.1	1.4	1.6	-0.2
Blood clot in the leg (DVT)	2.1	2.7	9.3	-0.3	-0.2	1.1	-1.5	-2.4	-1.3	-3.0	1.2
Medication: Paracetamol	3.1	5.2	13.8	0.9	0.9	3.7	-0.9	-3.0	-0.6	-2.7	3.0
Headache pain in last month	8.9	15.3	45.7	-1.0	-1.1	3.3	-4.6	-6.8	0.0	-6.0	2.6
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.3	0.5	0.1	1.5	0.1	-1.4	0.5	-0.8	1.0
Glaucoma (self-reported)	0.8	0.9	3.0	1.7	1.7	0.4	0.7	0.2	0.5	-0.4	0.3
Gout (self-reported)	1.0	1.4	4.2	0.1	0.6	0.5	1.7	2.0	-0.2	1.7	0.7
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	6.3	0.7	0.9	-1.0	1.1	0.7	2.5	1.1	-1.0
Medication: Amlodipine	0.6	0.8	1.8	-1.2	-1.2	-1.4	-1.1	0.2	-0.9	-0.0	0.2
Medication: Ventolin 100micrograms inhaler	1.5	1.9	3.9	-1.5	-1.1	-0.2	-1.7	-1.2	-1.7	-2.0	0.6
Birth weight	2.7	5.9	13.9	-1.8	-2.0	-3.0	1.0	3.7	-0.3	3.7	-1.6
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.0	0.5	0.6	1.4	0.5	-0.2	-0.1	-0.3	1.4
High blood pressure (siblings)	0.7	1.0	2.6	1.2	1.1	0.9	1.6	0.7	0.2	0.8	0.7
Forced vital capacity (FVC), Best measure	0.8	2.8	6.2	0.8	0.8	1.8	0.3	-2.5	2.4	-1.7	1.7
Body fat percentage	3.0	12.0	27.5	4.7	5.2	3.8	3.9	1.8	-3.0	1.3	1.4
Leg fat percentage (right)	3.4	12.4	25.5	4.6	5.0	4.5	3.3	1.0	-3.5	0.7	2.8
Arm fat-free mass (right)	0.6	2.9	8.8	3.0	2.4	0.6	2.0	0.6	1.2	1.6	0.2
Exposure to tobacco smoke outside home	0.8	1.1	2.4	0.7	0.9	1.5	-0.0	-0.7	-1.3	-0.7	1.5
Comparative body size at age 10	1.6	4.4	11.0	0.1	-0.0	-3.3	0.7	1.8	2.2	2.6	-3.1
Number of full brothers	0.6	0.7	2.9	0.7	1.2	0.3	0.8	0.7	0.0	0.0	1.7
Worry too long after embarrassment	0.9	1.5	5.7	-1.0	-0.9	-2.4	-0.2	0.8	1.3	0.0	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.4	3.3	-0.1	-0.0	-0.3	-1.1	-1.7	1.1	-1.8	1.5
Wheeze or whistling in the chest in last year	1.9	3.4	10.3	1.7	1.6	3.2	0.4	-1.4	-0.7	-1.9	2.3
Number of children fathered	2.8	3.1	6.4	0.0	-0.1	2.4	-0.9	-2.2	-1.0	-2.4	2.5
Reason for reducing amount of alcohol drunk: Health precaution	1.9	2.2	5.4	-2.3	-2.3	-1.8	-1.6	-0.2	0.5	-0.1	-1.1
Age at first live birth	0.2	0.3	0.9	0.1	0.4	-0.7	0.0	0.6	0.9	0.4	0.2
Pulse wave peak to peak time	1.5	1.7	3.6	-0.8	-1.1	-1.8	-0.0	1.8	-0.2	1.9	-1.3
Health satisfaction	1.3	1.7	3.3	1.4	1.4	1.2	-0.1	-1.5	1.8	-1.2	1.1
Shortness of breath walking on level ground	0.9	1.1	2.4	1.0	1.1	1.2	-0.6	-1.0	-1.2	-1.5	-0.3
Qualifications: College or University degree	1.4	4.3	8.8	-2.3	-1.9	0.3	-2.5	-2.7	0.3	-3.0	1.8
Eye problems/disorders: None of the above	0.2	0.2	0.8	-0.6	-0.9	-0.6	-0.2	0.5	-0.0	0.2	0.4
Mouth/teeth dental problems: Loose teeth	1.0	1.2	3.2	1.3	1.5	1.8	0.3	-0.7	-0.3	-0.5	1.3
Emphysema/chronic bronchitis	0.1	0.1	0.3	-0.1	-0.1	0.2	-0.2	0.3	-0.6	-0.3	0.1
Medication for pain relief, constipation, heartburn	5.1	8.7	17.1	-1.1	-1.2	-4.1	1.5	3.8	1.1	4.1	-3.8
Neck or shoulder pain in last month	1.4	2.0	4.5	1.2	1.2	2.1	0.0	-1.9	1.1	-1.7	1.2
Medication: Blood pressure	0.9	1.6	5.1	-0.1	0.3	-1.8	0.4	2.3	-0.6	1.6	-1.1
Angina (self-reported)	0.8	1.1	3.5	0.1	0.6	-1.0	1.0	1.9	0.1	1.3	-1.0
Migraine (self-reported)	4.4	5.5	16.9	-1.6	-1.7	0.6	-3.4	-4.1	0.7	-2.8	1.0
Medication: Ibuprofen	3.5	4.1	9.5	0.7	1.0	3.1	-0.7	-2.1	-1.7	-2.5	2.8
Medication: Allopurinol	1.3	1.8	3.2	1.1	1.5	1.3	1.8	1.3	-0.5	1.2	1.4
Medication: Omeprazole	4.9	5.8	13.5	2.2	2.2	3.7	0.7	-1.4	-2.8	-1.6	3.2
Medication: Seretide 50 evohaler	1.3	1.6	4.1	1.1	1.2	1.5	0.3	-0.1	-1.8	-0.5	2.0
Mean time to correctly identify matches	2.3	4.4	11.8	-2.3	-2.4	-3.4	-1.0	0.8	0.6	1.0	-3.2
Heart disease (mother)	0.2	0.3	1.3	0.2	0.1	0.2	1.1	0.6	0.4	0.7	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	1.7	-0.0	0.4	-0.5	-0.7	-0.7	-1.0	-0.6	-1.3
Whole body fat mass	2.9	12.2	29.6	5.2	5.4	3.4	4.2	2.0	-1.8	1.8	1.4
Leg fat mass (right)	3.5	13.5	31.2	5.4	5.6	4.0	4.0	1.5	-2.1	1.6	2.4
Arm predicted mass (right)	0.4	2.2	7.6	2.8	2.2	0.5	1.5	0.2	1.2	1.2	0.2
Pulse rate, automated reading	1.9	6.3	13.3	-2.9	-2.7	-0.6	-3.6	-2.4	-0.6	-3.6	-1.1
Alcohol intake frequency.	0.4	0.9	2.3	-0.2	-0.1	-1.2	0.3	0.7	1.1	1.2	-1.5
Comparative height size at age 10	0.7	3.8	9.5	2.9	3.1	2.3	2.3	0.7	-0.5	0.2	1.2
Number of full sisters	0.6	0.7	1.2	0.9	0.8	1.1	1.0	0.7	-0.9	0.1	-0.8
Suffer from ‘nerves’	0.6	1.0	3.2	0.0	0.3	-1.0	1.2	1.8	1.1	1.0	0.3
Overall health rating	0.6	1.2	2.2	1.2	1.5	1.3	-0.3	-1.1	1.0	-1.2	0.9
Chest pain or discomfort	1.1	1.5	4.6	1.3	1.5	2.1	0.8	-0.0	-0.6	-0.4	1.6
Had major operations	0.4	0.4	1.2	-0.2	-0.3	-0.8	-0.4	-0.7	0.9	-0.3	-1.1
Age at last live birth	0.3	0.5	2.0	0.5	0.6	-0.5	0.7	1.4	0.3	0.7	0.1
Family relationship satisfaction	2.5	3.0	6.0	-0.7	-1.1	-2.4	0.5	1.6	2.5	2.4	-1.5
Leg pain on walking	0.2	0.3	0.6	0.8	0.6	-0.2	0.7	0.6	-0.3	0.5	-0.5
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	5.2	-0.1	-0.2	-1.2	1.1	1.7	-1.3	1.3	-2.3
Commuting to job workplace: Car/motor vehicle	1.0	1.1	2.8	1.4	1.4	1.7	-0.1	-1.2	-0.1	-0.7	0.2
Illness, injury, bereavement, stress in last 2 years	3.4	4.2	9.8	-3.1	-2.7	-2.3	-2.3	-0.8	0.6	-1.4	-1.6
Medication: Aspirin	0.1	0.1	0.3	0.1	0.1	-0.4	0.3	0.6	0.3	0.3	0.1
Supplements: Vitamin C	1.3	1.5	4.1	1.6	1.7	1.0	1.0	-0.1	2.0	0.6	0.4
Knee pain experienced in last month	3.2	5.0	10.0	3.0	3.2	2.4	3.0	0.8	-0.6	0.8	2.0
Hypertension (Self-reported)	0.2	0.5	2.3	0.3	0.4	-0.2	-0.3	-0.7	1.5	-0.3	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	6.4	-0.1	0.1	1.4	-0.8	-1.4	-0.1	-2.5	0.4
Illnesses of father: Heart disease	0.7	0.9	1.8	1.3	1.3	1.3	0.8	-0.0	-0.7	-0.2	1.1
Illnesses of siblings: Diabetes	1.8	2.2	5.8	2.0	2.0	1.2	1.3	-0.2	2.4	0.2	0.9
Smoking status: Previous	0.3	0.4	0.9	0.9	0.8	0.6	0.9	0.1	-0.0	0.3	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	3.6	-0.5	-0.3	-1.0	-0.1	0.8	0.7	0.1	-1.9
Whole body fat-free mass	0.8	4.7	12.8	3.6	3.0	0.4	2.5	1.1	2.1	2.0	0.3
Leg fat-free mass (right)	0.8	4.5	12.5	3.5	3.0	0.5	2.4	1.0	2.1	1.7	-0.1
Arm fat percentage (left)	2.8	11.2	27.7	4.8	5.3	3.5	3.8	1.8	-1.9	1.7	1.4
Average weekly red wine intake	1.3	1.9	5.0	-1.0	-0.9	0.5	-1.6	-1.7	-0.2	-2.2	1.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.8	0.2	0.3	-0.8	-0.4	-0.3	1.7	-0.2	-0.1
Mood swings	0.8	1.4	5.1	-0.7	-0.9	-2.3	-0.5	0.6	1.7	0.9	-0.9
Loneliness, isolation	2.0	2.8	8.0	0.7	0.7	-1.1	2.0	2.3	1.6	2.8	-0.8
Long-standing illness, disability or infirmity	0.6	1.0	3.5	0.5	0.8	1.0	-0.2	-0.7	0.4	-1.4	1.9
Ever had bowel cancer screening	0.9	1.0	2.9	-0.8	-0.8	-1.6	-0.3	0.2	1.1	0.4	-1.7
Diabetes diagnosed by doctor	2.2	3.6	9.4	2.8	3.1	1.5	1.9	0.5	0.2	0.1	2.3
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	3.1	-0.7	-0.5	-1.2	0.1	1.3	-0.8	0.7	-1.8
Friendships satisfaction	5.8	7.1	19.2	-1.8	-2.2	-4.4	0.3	2.7	2.6	2.9	-2.7
Qualifications: nursing, teaching	0.2	0.4	1.7	0.3	0.5	-0.3	0.4	0.5	-0.5	0.3	1.3
Commuting to job workplace: Walk	0.8	0.9	1.8	0.5	0.2	-0.4	1.2	1.0	1.2	1.3	-0.9
Eye problems/disorders: Cataract	0.1	0.1	0.4	0.1	0.1	-0.3	0.5	-0.0	0.6	0.5	-0.4
Mouth/teeth dental problems: Mouth ulcers	1.1	1.7	6.3	0.9	0.7	0.1	0.4	-1.0	2.5	-0.5	2.2
Medication for cholesterol	1.4	2.2	5.7	0.9	0.5	-0.9	1.3	2.4	-1.1	2.0	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.9	5.8	18.1	-0.4	-0.7	0.8	-2.9	-4.3	0.5	-4.2	-0.2
Back pain experienced in last month	1.4	2.1	4.3	1.0	0.9	1.8	-0.2	-1.9	0.2	-1.8	2.1
Mineral and other dietary supplements	0.6	0.8	1.4	-1.1	-1.2	-1.2	-0.2	0.9	0.2	0.9	-0.7
Breast cancer (self-reported)	2.6	3.1	10.0	1.9	1.8	1.9	1.6	0.9	-1.1	0.4	3.2
Asthma (self-reported)	1.8	3.5	9.9	0.5	1.0	2.0	-0.9	-1.9	-2.1	-3.1	1.9
Osteoporosis (self-reported)	2.8	3.5	6.5	2.4	2.2	2.5	0.5	-1.7	1.2	-1.4	1.9
Osteoarthritis (self-reported)	3.8	5.0	14.6	-0.3	-0.2	1.7	-1.9	-2.4	-3.8	-3.1	1.8
Medication: Aspirin	0.0	0.1	0.2	-0.0	-0.0	0.0	0.2	0.4	0.4	0.1	0.2
Medication: Gliclazide	0.2	0.2	0.7	0.8	0.7	0.0	-0.2	-0.2	0.2	-0.2	0.7
Illnesses of father: None of the above (group 1)	0.3	0.3	1.1	-0.2	-0.2	0.3	-0.3	-1.1	0.7	-0.6	-0.5
Smoking status: Current	0.6	0.9	1.7	1.2	1.3	1.2	0.3	-0.7	-0.2	-0.8	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.5	5.2	17.9	0.5	0.7	2.5	-1.3	-4.2	2.0	-2.9	1.5
Whole body water mass	0.9	5.0	13.6	3.7	3.1	0.4	2.6	1.2	2.1	2.2	0.4
Leg predicted mass (right)	0.9	4.6	12.8	3.6	3.0	0.4	2.4	1.0	2.1	1.7	-0.1
Arm fat mass (left)	2.8	11.6	28.6	5.2	5.3	3.2	4.0	1.7	-1.0	2.1	1.3
Number of self-reported non-cancer illnesses	3.1	5.3	17.5	-0.7	-0.3	1.5	-2.6	-3.5	-1.1	-4.2	1.3
Average weekly champagne plus white wine intake	1.5	2.0	7.7	-2.4	-2.8	-1.2	-0.6	0.2	0.5	0.4	-0.4
Miserableness	0.4	0.6	2.1	0.7	1.0	0.6	0.7	0.3	0.7	0.2	1.5
Guilty feelings	3.8	5.8	13.2	0.7	0.7	-2.5	2.2	3.6	2.8	3.6	-0.1
Wears glasses or contact lenses	1.2	1.4	2.7	-1.4	-1.4	-1.6	-0.6	0.9	-1.3	0.6	-1.2
Ever taken oral contraceptive pill	1.7	1.9	5.1	2.0	1.9	2.2	1.1	-0.1	-0.6	-0.2	1.0
Hearing aid user	1.8	2.1	6.1	1.0	1.2	1.5	1.7	1.4	-0.8	0.8	2.5
Mother’s age at death	0.9	1.1	2.4	1.2	1.4	0.8	0.9	-0.2	1.2	0.4	1.6
Financial situation satisfaction	0.8	1.0	1.8	1.3	1.0	0.6	1.4	1.2	0.5	1.2	0.4
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.5	-0.2	-0.1	0.5	-0.7	-1.4	-0.3	-1.6	0.2
Commuting to job workplace: Public transport	1.7	2.1	7.3	-1.8	-1.7	-2.7	-0.5	0.9	-0.4	1.0	-1.0
Eye problems/disorders: Glaucoma	0.3	0.3	1.4	1.2	1.0	0.1	0.3	0.3	0.3	0.1	-0.1
Medication: Blood pressure	0.6	1.2	3.1	-0.4	-0.5	0.2	-1.0	-1.7	1.8	-1.4	0.5
Pain type(s) experienced in last month: Hip pain	5.0	6.3	15.4	1.5	1.3	3.9	-0.2	-3.2	-0.8	-3.3	3.1
Supplements: Fish oil (including cod liver oil)	0.9	1.1	3.1	1.7	1.8	0.6	1.1	-0.1	1.2	0.1	0.3
High cholesterol (Self-reported)	1.4	2.6	7.0	-0.3	0.1	1.5	-1.6	-2.5	-0.8	-2.6	1.3
Medication: Bendroflumethiazide	0.1	0.1	0.5	-0.3	-0.3	0.1	-0.2	-0.1	-0.1	-0.2	-0.7
Medication: Paracetamol	3.5	5.5	12.5	0.7	0.7	3.5	-0.9	-2.7	-1.8	-2.6	3.5
Medication: Lisinopril	0.5	0.6	2.9	-0.0	0.1	0.8	0.3	-0.0	1.1	-0.4	1.7
Medication: Atorvastatin	1.6	2.0	4.7	-1.3	-0.9	0.1	-2.0	-1.9	-1.1	-2.2	0.4
Illnesses of father: High blood pressure	3.1	3.8	11.9	-0.1	0.0	-1.6	1.9	3.5	0.9	3.1	-1.4
Alcohol drinker status: Never	0.6	0.7	2.3	-0.4	-0.5	0.2	-1.1	-1.1	1.5	-0.5	0.4
Ever smoked	0.1	0.2	0.3	0.5	0.6	-0.1	0.5	0.0	0.4	0.2	0.5
Basal metabolic rate	1.1	6.0	16.8	4.1	3.6	1.1	3.0	1.3	1.4	2.1	0.5
Leg fat percentage (left)	2.3	8.5	17.7	3.7	4.2	3.6	2.7	0.9	-3.4	0.5	1.8
Arm fat-free mass (left)	0.8	3.8	11.5	3.4	2.9	0.5	2.2	1.0	1.2	1.9	0.4
Number of operations (self-reported)	2.3	3.4	10.5	-0.3	-0.5	1.3	-1.9	-3.2	-0.3	-2.7	1.9
Average weekly beer plus cider intake	1.3	1.9	4.8	0.9	1.0	-0.1	1.6	1.7	0.2	2.2	-1.7
Irritability	0.0	0.1	0.3	-0.2	-0.1	-0.3	0.0	0.5	0.2	0.2	-0.3
Risk taking	0.6	0.9	2.4	-0.8	-0.7	-0.9	-0.9	-0.9	0.7	-0.7	-1.5
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.0	-1.2	-1.4	-1.4	-0.4	0.3	0.7	0.7	-0.2
Fractured/broken bones in last 5 years	1.2	1.6	4.9	0.5	0.7	2.2	-0.1	-1.4	-0.7	-1.7	1.4
Age started oral contraceptive pill	3.1	3.8	8.0	-2.2	-2.5	0.1	-2.4	-2.3	-0.5	-2.8	0.3
Diastolic blood pressure, automated reading	1.0	3.0	6.3	-1.4	-1.3	0.8	-2.1	-2.4	-0.4	-2.5	1.7
Ever depressed for a whole week	0.4	0.5	2.0	-0.1	0.2	0.4	-0.3	-1.1	-0.0	-1.4	0.4
Unable to work because of sickness or disability	0.2	0.3	0.8	-0.3	0.1	-0.8	0.1	0.4	0.9	-0.3	0.6
Commuting to job workplace: Cycle	0.3	0.4	1.5	0.7	0.5	-0.3	-0.2	0.7	-1.2	-0.5	0.4
Myopia	0.9	1.2	3.2	-1.0	-1.2	-0.9	-0.8	-1.5	1.8	-0.7	-0.3
Vascular/heart problems diagnosed by doctor	0.1	0.4	2.0	0.0	-0.2	0.8	0.4	0.3	-1.4	0.1	0.2
Cholesterol lowering medication	1.4	2.1	5.2	-0.3	-0.2	1.2	-1.3	-2.2	0.9	-2.3	1.7
Medication: Omeprazole (e.g. Zanprol)	3.4	4.2	10.5	2.1	2.0	3.2	0.7	-1.0	-2.3	-1.3	2.4
Pain experienced in last month	3.8	6.4	14.7	-2.2	-2.1	-3.2	0.9	3.8	-0.4	2.9	-2.8
Supplements: Calcium	1.5	1.7	4.0	0.5	0.8	1.6	-0.2	-1.5	-0.7	-1.8	2.0
Basal cell carcinoma (self-reported)	2.7	3.3	10.6	2.0	1.8	3.3	1.4	0.3	-1.1	0.1	2.3
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.5	-1.6	-1.2	-1.5	-0.2	1.0	0.4	0.7	-1.4
Deep venous thrombosis (DVT) (self-reported)	2.9	3.7	11.6	-0.3	-0.2	1.4	-1.7	-2.7	-1.7	-3.4	1.6
Heart disease (siblings)	0.3	0.4	1.7	0.5	0.7	1.3	0.6	-0.3	0.4	-0.3	-0.4
Alcohol drinker status: Previous	0.9	1.1	2.9	-1.0	-0.6	0.5	-1.2	-1.7	0.2	-1.6	0.0
Pack years of smoking	0.6	0.9	5.2	0.6	0.3	-0.0	0.4	0.6	-2.3	0.2	0.8
Impedance of whole body	0.5	2.6	13.4	-1.1	-0.4	1.6	0.5	1.1	-3.7	-1.2	-0.4
Leg fat mass (left)	2.7	10.4	24.5	4.8	4.9	3.4	3.5	1.5	-2.3	1.4	1.8
Arm predicted mass (left)	0.9	4.6	13.5	3.7	3.1	0.6	2.4	1.1	1.1	2.1	0.3