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chr1:242,590,540-244,359,621

Best TWAS P=2.76e-09 · Best GWAS P=1.8e-08 conditioned to 0.102

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CEP170	0.05	0.02	bslmm	378	0.03	1.9e-04	4.7	-5.4	6.9e-08	-0.50	0.23	0.37	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SDCCAG8	0.13	0.10	enet	32	0.11	5.6e-13	4.9	-5.1	2.7e-07	-0.62	0.11	0.88	FALSE
3	GTEx	Adipose Subcutaneous	SDCCAG8	0.18	0.10	enet	25	0.11	1.4e-09	5.2	5.2	2.2e-07	0.86	0.02	0.98	FALSE
4	GTEx	Breast Mammary Tissue	SDCCAG8	0.15	0.04	enet	13	0.09	2.8e-05	4.8	5.8	8.2e-09	0.85	0.03	0.96	FALSE
5	GTEx	Breast Mammary Tissue (Female)	CEP170	0.26	0.04	lasso	4	0.09	1.5e-03	5.1	5.3	1.2e-07	0.80	0.03	0.70	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	SDCCAG8	0.36	0.24	lasso	8	0.34	5.7e-12	4.4	5.6	2.7e-08	0.89	0.02	0.98	FALSE
7	GTEx	Cells Transformed fibroblasts	SDCCAG8	0.23	0.25	enet	13	0.28	3.5e-21	5.2	5.5	4.5e-08	0.90	0.04	0.96	FALSE
8	GTEx	Cells Transformed fibroblasts	RP11-261C10.5	0.15	0.13	lasso	2	0.14	2.2e-10	5.2	5.2	2.3e-07	0.93	0.02	0.97	FALSE
9	GTEx	Colon Transverse	SDCCAG8	0.17	0.02	lasso	3	0.02	2.8e-02	5.2	5.2	2.3e-07	0.90	0.03	0.89	FALSE
10	GTEx	Esophagus Muscularis	CEP170	0.09	0.11	lasso	4	0.10	1.2e-06	5.3	5.2	1.7e-07	0.85	0.04	0.96	FALSE
11	GTEx	Nerve Tibial	SDCCAG8	0.25	0.27	enet	14	0.27	2.3e-19	5.1	5.6	2.0e-08	0.87	0.06	0.94	FALSE
12	GTEx	Nerve Tibial	CEP170	0.09	0.08	lasso	1	0.05	1.1e-04	5.1	5.1	2.8e-07	0.85	0.04	0.95	FALSE
13	GTEx	Prostate	CEP170	0.28	0.05	lasso	4	0.12	6.9e-04	5.4	6.0	2.8e-09	0.77	0.03	0.73	TRUE
14	GTEx	Whole Blood	SDCCAG8	0.18	0.15	lasso	7	0.14	6.2e-13	5.4	5.5	3.8e-08	0.97	0.01	0.99	FALSE
15	METSIM	Adipose	SDCCAG8	0.12	0.13	enet	17	0.14	5.6e-21	5.6	5.9	4.0e-09	0.95	0.01	0.99	FALSE
16	NTR	Blood	SDCCAG8	0.03	0.01	blup	356	0.01	1.4e-04	4.8	5.8	5.7e-09	0.69	0.05	0.94	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SDCCAG8	0.19	0.18	lasso	5	0.16	1.9e-07	5.4	5.2	2.3e-07	0.92	0.01	0.99	FALSE