Best TWAS P=6.93e-08 · Best GWAS P=6.93e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RARRES1 | 0.14 | 0.13 | lasso | 6 | 0.17 | 8.9e-20 | -5.3 | 5.2 | 2.6e-07 | -0.89 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | RARRES1 | 0.16 | 0.30 | lasso | 1 | 0.27 | 1.1e-07 | -5.4 | 5.4 | 6.9e-08 | -1.00 | 0.00 | 0.99 | TRUE |
| 3 | GTEx | Brain Hippocampus | RP11-379F4.7 | 0.25 | 0.08 | lasso | 6 | 0.08 | 7.5e-03 | -5.4 | 5.3 | 9.7e-08 | -0.98 | 0.01 | 0.84 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | RP11-379F4.7 | 0.04 | 0.01 | lasso | 3 | 0.01 | 1.2e-01 | -5.3 | 5.2 | 1.7e-07 | -0.99 | 0.02 | 0.91 | FALSE |
| 5 | GTEx | Heart Left Ventricle | MLF1 | 0.26 | 0.24 | lasso | 9 | 0.28 | 2.5e-15 | -4.5 | 5.1 | 3.0e-07 | -0.89 | 0.02 | 0.98 | FALSE |