Best TWAS P=1.57e-07 · Best GWAS P=4.18e-08 conditioned to 0.0283
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | FHL5 | 0.04 | 0.03 | bslmm | 444 | 0.02 | 0.0029 | -4.5 | 5.2 | 1.6e-07 | -0.79 | 0.07 | 0.89 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | FHL5 | 0.03 | 0.03 | enet | 3 | 0.02 | 0.0019 | -5.5 | 5.2 | 1.7e-07 | -0.96 | 0.00 | 0.90 | FALSE |