Hub : Traits :

Pain experienced in last month

52 significantly associated models · 30 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	2	207107801	208531683	1	1	1.6e-08	3.1e-08	0.183	94	CPO
2	3	48702606	50636111	7	1	1.5e-08	3.2e-07	0.013	76	GPX1
3	5	169590807	171419658	2	2	1.0e-07	1.5e-06	0.285	95	GABRP RANBP17
4	6	96314776	97756290	1	1	1.6e-07	4.2e-08	0.028	84	FHL5
5	7	511203	1607259	2	1	1.3e-07	2.8e-06	0.300	95	SUN1
6	9	127218258	128680148	2	1	1.8e-10	1.5e-08	0.537	99	PPP6C
7	12	55694116	58303535	2	2	3.8e-10	8.0e-10	1.000	100	LRP1 SUOX
8	14	54820582	56233069	1	1	4.8e-09	1.6e-05	0.134	88	MAPK1IP1L
9	16	71070698	72838680	5	1	8.6e-09	3.3e-09	0.033	87	ATXN1L
10	20	30179027	31870640	3	1	1.9e-08	1.3e-07	0.107	91	KIF3B

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Depressed Affect (Nagel 2018)	4.03	2	1	2.2	0.00	1.0000	GPX1 LRP1
Depression (Nagel 2018)	2.28	1	0	0.0	0.00	1.0000	ATXN1L
Intelligence (Savage-Jansen 2018)	5.74	3	2	4.4	0.00	1.0000	ATXN1L GPX1 SUOX
Neuroticism (Nagel 2018)	2.08	1	0	0.0	0.00	1.0000	GPX1
Crohns Disease (2017)	3.23	2	1	2.2	0.00	1.0000	GPX1 KIF3B
Irritable Bowel Disease (IBD)	4.63	2	1	2.2	0.00	1.0000	GPX1 KIF3B
Ulcerative Colitis (UC)	3.77	2	1	2.2	0.00	1.0000	GPX1 KIF3B
Major Depression (MDD)	3.72	2	0	0.0	0.00	1.0000	CPO GPX1
Verbal and Numeric Reasoning (VNR)	4.68	3	1	2.2	0.00	1.0000	ATXN1L GPX1 SUOX
Breast Cancer	1.65	2	0	0.0	0.00	1.0000	ATXN1L GPX1
Prostate Cancer	3.50	1	0	0.0	0.00	1.0000	GPX1
Age at First Birth	7.93	4	1	2.2	0.58	0.4170	GPX1 KIF3B RANBP17 SUOX
Crohns Disease (2012)	2.33	1	1	2.2	0.00	1.0000	GPX1
Neuroticism (2016)	3.22	2	0	0.0	0.00	1.0000	CPO GPX1
Primary Biliary Cirrhosis	2.26	2	0	0.0	0.00	1.0000	LRP1 SUOX
Ulcerative Colitis	3.63	2	1	2.2	0.00	1.0000	GPX1 KIF3B
Blood Eosinophil Count	2.68	5	3	6.7	0.71	0.1822	GPX1 LRP1 MAPK1IP1L SUN1 SUOX
Blood Platelet Count	0.92	5	1	2.2	0.23	0.7154	ATXN1L CPO KIF3B MAPK1IP1L SUN1
Blood Red Count	0.81	4	1	2.2	0.25	0.7472	ATXN1L KIF3B MAPK1IP1L SUOX
Blood White Count	0.83	2	1	2.2	0.00	1.0000	FHL5 GPX1
Heel T-Score	0.29	1	0	0.0	0.00	1.0000	SUOX
BMI	4.36	7	3	6.7	-0.67	0.1004	FHL5 GABRP GPX1 LRP1 RANBP17 SUN1 SUOX
Height	0.81	5	3	6.7	0.05	0.9312	ATXN1L CPO GPX1 KIF3B LRP1
Waist Hip Ratio (WHR)	1.60	2	1	2.2	0.00	1.0000	GPX1 PPP6C
Systolic Blood Pressure	2.98	5	3	6.7	-0.18	0.7673	ATXN1L FHL5 GPX1 MAPK1IP1L SUOX
Smoking Status	5.16	5	3	6.7	-0.60	0.2852	GPX1 KIF3B PPP6C RANBP17 SUOX
Allergy or Eczema	4.44	3	1	2.2	0.00	1.0000	CPO LRP1 SUOX
Cardiovascular Disease	2.26	5	0	0.0	-0.54	0.3501	ATXN1L FHL5 GPX1 RANBP17 SUOX
Hypothyroidism (self reported)	3.02	1	1	2.2	0.00	1.0000	SUOX
Respiratory disease	5.31	4	2	4.4	0.76	0.2361	CPO FHL5 LRP1 SUOX
Lung FEV1/FVC ratio	4.22	3	2	4.4	0.00	1.0000	GPX1 LRP1 SUOX
Lung FVC	1.29	2	1	2.2	0.00	1.0000	GPX1 SUOX
Neuroticism	3.12	4	1	2.2	-0.96	0.0395	ATXN1L CPO GPX1 PPP6C
Chronotype (morning person)	1.48	2	0	0.0	0.00	1.0000	GPX1 KIF3B
Hair Pigment	0.19	3	0	0.0	0.00	1.0000	ATXN1L LRP1 SUOX
Tanning	0.39	2	1	2.2	0.00	1.0000	ATXN1L KIF3B
Number of treatments/medications taken	4.35	2	1	2.2	0.00	1.0000	GPX1 LRP1
Sensitivity / hurt feelings	1.79	1	0	0.0	0.00	1.0000	LRP1
Frequency of depressed mood in last 2 weeks	2.87	1	0	0.0	0.00	1.0000	CPO
Hearing difficulty/problems: Yes	2.63	2	0	0.0	0.00	1.0000	ATXN1L CPO
Other serious medical condition/disability diagnosed by doctor	2.29	1	0	0.0	0.00	1.0000	KIF3B
Systolic blood pressure, automated reading	3.04	3	2	4.4	0.00	1.0000	ATXN1L FHL5 GPX1
Angina	2.06	1	0	0.0	0.00	1.0000	CPO
Vitamin and mineral supplements	3.07	1	1	2.2	0.00	1.0000	LRP1
Medication: Co-codamol	4.14	1	0	0.0	0.00	1.0000	GPX1
Pack years adult smoking proportion	3.37	1	0	0.0	0.00	1.0000	GPX1
Impedance of leg (right)	2.80	5	1	2.2	0.64	0.2407	CPO GPX1 RANBP17 SUN1 SUOX
Leg fat-free mass (left)	2.53	6	1	2.2	-0.63	0.1778	ATXN1L CPO GPX1 RANBP17 SUN1 SUOX
Trunk fat percentage	1.81	3	0	0.0	0.00	1.0000	GPX1 LRP1 RANBP17
Hand grip strength (right)	2.31	3	0	0.0	0.00	1.0000	LRP1 PPP6C RANBP17
Townsend deprivation index at recruitment	3.76	1	0	0.0	0.00	1.0000	PPP6C
Current tobacco smoking	3.84	3	0	0.0	0.00	1.0000	CPO GPX1 PPP6C
Average weekly fortified wine intake	2.02	1	0	0.0	0.00	1.0000	SUOX
Maternal smoking around birth	2.55	1	0	0.0	0.00	1.0000	GPX1
Fed-up feelings	4.60	2	1	2.2	0.00	1.0000	ATXN1L GPX1
Frequency of unenthusiasm / disinterest in last 2 weeks	3.23	2	0	0.0	0.00	1.0000	ATXN1L GPX1
Relative age voice broke	2.22	1	0	0.0	0.00	1.0000	CPO
Taking other prescription medications	3.11	1	1	2.2	0.00	1.0000	GPX1
Age when periods started (menarche)	3.92	3	2	4.4	0.00	1.0000	GPX1 PPP6C SUOX
Bilateral oophorectomy (both ovaries removed)	1.83	1	0	0.0	0.00	1.0000	ATXN1L
Qualifications: CSEs or equivalent	3.41	2	0	0.0	0.00	1.0000	GPX1 KIF3B
High blood pressure	1.65	2	0	0.0	0.00	1.0000	FHL5 SUOX
Hayfever, allergic rhinitis or eczema	4.49	2	1	2.2	0.00	1.0000	LRP1 SUOX
Multivitamins +/- minerals	2.01	1	0	0.0	0.00	1.0000	LRP1
Supplements: Glucosamine	2.13	1	0	0.0	0.00	1.0000	MAPK1IP1L
Medication: Levothyroxine sodium	2.64	1	1	2.2	0.00	1.0000	SUOX
Sitting height	1.11	3	1	2.2	0.00	1.0000	ATXN1L KIF3B LRP1
Body mass index (BMI)	4.55	3	3	6.7	0.00	1.0000	GPX1 RANBP17 SUOX
Impedance of leg (left)	2.83	6	2	4.4	0.36	0.4829	CPO GPX1 KIF3B RANBP17 SUN1 SUOX
Leg predicted mass (left)	2.51	6	1	2.2	-0.64	0.1717	ATXN1L CPO GPX1 RANBP17 SUN1 SUOX
Trunk fat mass	2.20	4	2	4.4	-0.98	0.0179	GABRP GPX1 RANBP17 SUOX
Waist circumference	2.63	3	2	4.4	0.00	1.0000	GPX1 RANBP17 SUOX
Past tobacco smoking	3.32	2	0	0.0	0.00	1.0000	PPP6C RANBP17
Alcohol usually taken with meals	2.93	2	0	0.0	0.00	1.0000	PPP6C SUOX
Frequency of tenseness / restlessness in last 2 weeks	3.78	2	1	2.2	0.00	1.0000	CPO GPX1
Hearing difficulty/problems with background noise	2.58	2	0	0.0	0.00	1.0000	ATXN1L CPO
Had other major operations	1.47	1	0	0.0	0.00	1.0000	RANBP17
Forced vital capacity (FVC)	1.55	2	1	2.2	0.00	1.0000	ATXN1L GPX1
Ever unenthusiastic/disinterested for a whole week	2.07	1	0	0.0	0.00	1.0000	GPX1
Qualifications: None of the above	5.78	3	2	4.4	0.00	1.0000	ATXN1L GPX1 SUOX
Financial difficulties in last 2 years	4.32	3	0	0.0	0.00	1.0000	CPO GPX1 KIF3B
Mouth/teeth dental problems	3.28	1	0	0.0	0.00	1.0000	KIF3B
Allergy	5.26	3	1	2.2	0.00	1.0000	FHL5 LRP1 SUOX
Pain all over the body in last month	3.07	1	0	0.0	0.00	1.0000	GPX1
Hayfever/allergic rhinitis (self-reported)	3.78	2	0	0.0	0.00	1.0000	LRP1 SUOX
Fluid intelligence score	4.65	3	1	2.2	0.00	1.0000	ATXN1L GPX1 SUOX
Neuroticism score	2.81	2	1	2.2	0.00	1.0000	GPX1 PPP6C
Weight	2.95	6	2	4.4	-0.74	0.0926	ATXN1L CPO GABRP GPX1 RANBP17 SUOX
Impedance of arm (right)	4.04	4	3	6.7	0.93	0.0735	ATXN1L GPX1 SUN1 SUOX
Arm fat percentage (right)	2.89	5	2	4.4	-0.55	0.3412	GABRP GPX1 LRP1 RANBP17 SUOX
Trunk fat-free mass	2.41	6	2	4.4	-0.65	0.1634	ATXN1L CPO GPX1 LRP1 SUN1 SUOX
Hip circumference	2.21	3	1	2.2	0.00	1.0000	GPX1 RANBP17 SUOX
Alcohol intake versus 10 years previously	2.04	1	0	0.0	0.00	1.0000	GPX1
Father's age at death	2.78	1	0	0.0	0.00	1.0000	GPX1
Frequency of tiredness / lethargy in last 2 weeks	4.26	2	0	0.0	0.00	1.0000	CPO GPX1
Falls in the last year	3.06	1	0	0.0	0.00	1.0000	SUN1
Number of live births	1.62	1	0	0.0	0.00	1.0000	ATXN1L
Forced expiratory volume in 1-second (FEV1)	2.42	4	1	2.2	0.49	0.5130	ATXN1L GPX1 PPP6C SUOX
Qualifications: A levels/AS levels or equivalent	5.41	2	1	2.2	0.00	1.0000	GPX1 SUOX
Mouth/teeth dental problems: Dentures	2.69	2	0	0.0	0.00	1.0000	GPX1 KIF3B
Asthma	4.70	2	1	2.2	0.00	1.0000	LRP1 SUOX
Medication: Ibuprofen (e.g. Nurofen)	6.49	1	1	2.2	0.00	1.0000	LRP1
Lung cancer (father)	1.83	1	0	0.0	0.00	1.0000	GPX1
Forced expiratory volume in 1-second (FEV1), Best measure	2.50	3	1	2.2	0.00	1.0000	ATXN1L GPX1 SUOX
Impedance of arm (left)	4.48	5	2	4.4	0.73	0.1622	ATXN1L CPO GPX1 SUN1 SUOX
Arm fat mass (right)	3.51	4	3	6.7	-0.99	0.0127	GABRP GPX1 RANBP17 SUOX
Trunk predicted mass	2.43	6	2	4.4	-0.66	0.1576	ATXN1L CPO GPX1 LRP1 SUN1 SUOX
Standing height	0.86	3	1	2.2	0.00	1.0000	ATXN1L GPX1 LRP1
Exposure to tobacco smoke at home	2.80	1	0	0.0	0.00	1.0000	GPX1
Birth weight of first child	2.10	1	0	0.0	0.00	1.0000	SUOX
Peak expiratory flow (PEF)	1.59	1	0	0.0	0.00	1.0000	PPP6C
Ever highly irritable/argumentative for 2 days	2.75	1	0	0.0	0.00	1.0000	GPX1
Qualifications: O levels/GCSEs or equivalent	3.58	2	0	0.0	0.00	1.0000	ATXN1L GPX1
Medication: Paracetamol	9.20	6	1	2.2	-0.95	0.0038	CPO FHL5 GPX1 LRP1 RANBP17 SUOX
Headache pain in last month	16.53	5	2	4.4	-0.91	0.0335	FHL5 GABRP KIF3B LRP1 SUOX
Hypothyroidism/myxoedema (self-reported)	2.69	1	1	2.2	0.00	1.0000	SUOX
Medication: Ventolin 100micrograms inhaler	3.03	2	0	0.0	0.00	1.0000	CPO SUOX
Birth weight	1.54	2	0	0.0	0.00	1.0000	LRP1 SUOX
Forced vital capacity (FVC), Best measure	1.80	2	1	2.2	0.00	1.0000	ATXN1L GPX1
Body fat percentage	2.42	3	1	2.2	0.00	1.0000	GPX1 LRP1 RANBP17
Leg fat percentage (right)	3.81	4	1	2.2	0.70	0.3012	GPX1 LRP1 RANBP17 SUOX
Arm fat-free mass (right)	2.88	5	3	6.7	-0.73	0.1571	ATXN1L CPO GPX1 SUN1 SUOX
Exposure to tobacco smoke outside home	2.49	1	0	0.0	0.00	1.0000	GPX1
Comparative body size at age 10	1.64	3	0	0.0	0.00	1.0000	GABRP KIF3B PPP6C
Number of full brothers	2.40	1	0	0.0	0.00	1.0000	GPX1
Wheeze or whistling in the chest in last year	2.71	1	0	0.0	0.00	1.0000	GPX1
Reason for reducing amount of alcohol drunk: Health precaution	2.35	1	0	0.0	0.00	1.0000	SUOX
Age at first live birth	5.89	4	1	2.2	0.34	0.6615	ATXN1L GPX1 RANBP17 SUOX
Health satisfaction	3.51	2	0	0.0	0.00	1.0000	GPX1 MAPK1IP1L
Qualifications: College or University degree	7.11	6	2	4.4	0.75	0.0840	ATXN1L GPX1 PPP6C RANBP17 SUN1 SUOX
Medication for pain relief, constipation, heartburn	9.48	6	2	4.4	0.95	0.0038	CPO FHL5 GPX1 KIF3B LRP1 RANBP17
Neck or shoulder pain in last month	8.04	5	1	2.2	-0.99	0.0013	ATXN1L GABRP GPX1 KIF3B SUOX
Angina (self-reported)	1.92	1	0	0.0	0.00	1.0000	CPO
Migraine (self-reported)	8.35	2	1	2.2	0.00	1.0000	FHL5 LRP1
Medication: Ibuprofen	5.55	1	1	2.2	0.00	1.0000	LRP1
Medication: Seretide 50 evohaler	2.75	1	0	0.0	0.00	1.0000	GPX1
Mean time to correctly identify matches	1.44	1	0	0.0	0.00	1.0000	CPO
Whole body fat mass	2.84	3	2	4.4	0.00	1.0000	GPX1 RANBP17 SUOX
Leg fat mass (right)	3.96	4	2	4.4	-0.96	0.0440	GABRP GPX1 RANBP17 SUOX
Arm predicted mass (right)	2.94	5	3	6.7	-0.74	0.1558	ATXN1L CPO GPX1 SUN1 SUOX
Pulse rate, automated reading	0.95	1	0	0.0	0.00	1.0000	SUOX
Alcohol intake frequency.	2.82	3	0	0.0	0.00	1.0000	GPX1 LRP1 SUOX
Comparative height size at age 10	1.15	2	1	2.2	0.00	1.0000	ATXN1L GPX1
Overall health rating	6.87	5	3	6.7	-0.93	0.0216	ATXN1L CPO GPX1 PPP6C SUOX
Chest pain or discomfort	3.58	2	0	0.0	0.00	1.0000	CPO GPX1
Age at last live birth	3.99	1	1	2.2	0.00	1.0000	GPX1
Leg pain on walking	3.55	2	0	0.0	0.00	1.0000	GPX1 MAPK1IP1L
Qualifications: NVQ or HND or HNC or equivalent	2.99	2	0	0.0	0.00	1.0000	KIF3B SUN1
Medication: Aspirin	2.28	1	0	0.0	0.00	1.0000	CPO
Knee pain experienced in last month	4.67	4	0	0.0	-0.99	0.0087	GPX1 MAPK1IP1L PPP6C SUN1
Hypertension (Self-reported)	1.75	2	0	0.0	0.00	1.0000	FHL5 SUOX
Smoking status: Previous	2.43	1	0	0.0	0.00	1.0000	RANBP17
Whole body fat-free mass	2.55	6	3	6.7	-0.64	0.1734	ATXN1L CPO GPX1 RANBP17 SUN1 SUOX
Leg fat-free mass (right)	2.47	6	1	2.2	-0.59	0.2157	ATXN1L CPO GPX1 RANBP17 SUN1 SUOX
Arm fat percentage (left)	2.63	5	2	4.4	-0.52	0.3638	GABRP GPX1 LRP1 RANBP17 SUOX
Mood swings	3.94	1	1	2.2	0.00	1.0000	GPX1
Loneliness, isolation	3.24	1	0	0.0	0.00	1.0000	GPX1
Long-standing illness, disability or infirmity	2.50	2	0	0.0	0.00	1.0000	CPO KIF3B
Qualifications: nursing, teaching	2.73	1	0	0.0	0.00	1.0000	GPX1
Back pain experienced in last month	6.92	4	0	0.0	-0.99	0.0050	ATXN1L GABRP RANBP17 SUN1
Mineral and other dietary supplements	2.37	1	0	0.0	0.00	1.0000	LRP1
Asthma (self-reported)	4.87	3	1	2.2	0.00	1.0000	FHL5 LRP1 SUOX
Osteoarthritis (self-reported)	1.81	1	0	0.0	0.00	1.0000	GPX1
Medication: Aspirin	2.07	1	0	0.0	0.00	1.0000	CPO
Medication: Gliclazide	1.62	1	0	0.0	0.00	1.0000	GABRP
Smoking status: Current	3.63	2	0	0.0	0.00	1.0000	GPX1 PPP6C
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.39	3	0	0.0	0.00	1.0000	CPO GPX1 SUOX
Whole body water mass	2.61	6	3	6.7	-0.64	0.1692	ATXN1L CPO GPX1 RANBP17 SUN1 SUOX
Leg predicted mass (right)	2.45	6	1	2.2	-0.60	0.2126	ATXN1L CPO GPX1 RANBP17 SUN1 SUOX
Arm fat mass (left)	3.37	4	3	6.7	-0.99	0.0118	GABRP GPX1 RANBP17 SUOX
Average weekly champagne plus white wine intake	2.01	1	0	0.0	0.00	1.0000	SUOX
Miserableness	4.05	1	1	2.2	0.00	1.0000	GPX1
Guilty feelings	2.43	2	0	0.0	0.00	1.0000	GPX1 MAPK1IP1L
Financial situation satisfaction	3.10	1	1	2.2	0.00	1.0000	GPX1
Pain type(s) experienced in last month: Hip pain	3.84	1	0	0.0	0.00	1.0000	MAPK1IP1L
Supplements: Fish oil (including cod liver oil)	2.43	1	0	0.0	0.00	1.0000	LRP1
Medication: Paracetamol	8.95	6	1	2.2	-0.97	0.0016	CPO FHL5 GPX1 LRP1 RANBP17 SUOX
Ever smoked	3.20	2	0	0.0	0.00	1.0000	PPP6C RANBP17
Basal metabolic rate	2.74	6	3	6.7	-0.67	0.1462	ATXN1L CPO GPX1 RANBP17 SUN1 SUOX
Leg fat percentage (left)	3.73	4	1	2.2	0.71	0.2931	GPX1 LRP1 RANBP17 SUOX
Arm fat-free mass (left)	3.27	6	3	6.7	-0.67	0.1447	ATXN1L CPO GPX1 RANBP17 SUN1 SUOX
Number of operations (self-reported)	3.37	3	0	0.0	0.00	1.0000	GPX1 LRP1 RANBP17
Average weekly beer plus cider intake	1.94	1	0	0.0	0.00	1.0000	GPX1
Irritability	1.62	1	0	0.0	0.00	1.0000	GPX1
Age started oral contraceptive pill	4.67	3	0	0.0	0.00	1.0000	GPX1 RANBP17 SUOX
Diastolic blood pressure, automated reading	2.63	3	1	2.2	0.00	1.0000	FHL5 GPX1 SUOX
Myopia	2.66	1	0	0.0	0.00	1.0000	LRP1
Vascular/heart problems diagnosed by doctor	1.91	3	0	0.0	0.00	1.0000	ATXN1L FHL5 SUOX
Pack years of smoking	2.72	1	0	0.0	0.00	1.0000	GPX1
Impedance of whole body	3.91	6	3	6.7	0.40	0.4327	CPO GPX1 PPP6C RANBP17 SUN1 SUOX
Leg fat mass (left)	3.96	4	2	4.4	-0.95	0.0456	GABRP GPX1 RANBP17 SUOX
Arm predicted mass (left)	3.29	5	3	6.7	-0.73	0.1642	ATXN1L CPO GPX1 SUN1 SUOX

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	1	0.029	1.7
GTEx	Adipose Visceral Omentum	0	0.000	1.7
GTEx	Adrenal Gland	3	0.206	1.8
GTEx	Artery Aorta	0	0.000	1.7
GTEx	Artery Coronary	0	0.000	1.8
GTEx	Artery Tibial	3	0.080	1.7
GTEx	Brain Caudate basal ganglia	0	0.000	1.7
GTEx	Brain Cerebellar Hemisphere	0	0.000	1.9
GTEx	Brain Cerebellum	2	0.101	1.8
GTEx	Brain Cortex	0	0.000	1.7
GTEx	Brain Frontal Cortex BA9	1	0.108	1.9
GTEx	Brain Hippocampus	0	0.000	1.7
GTEx	Brain Hypothalamus	0	0.000	1.6
GTEx	Brain Nucleus accumbens basal ganglia	0	0.000	1.6
GTEx	Brain Putamen basal ganglia	0	0.000	1.7
GTEx	Breast Mammary Tissue	0	0.000	1.7
GTEx	Breast Mammary Tissue (Male)	0	0.000	1.7
GTEx	Breast Mammary Tissue (Female)	0	0.000	1.7
GTEx	Cells EBV-transformed lymphocytes	1	0.070	1.9
GTEx	Cells Transformed fibroblasts	1	0.024	1.7
GTEx	Colon Sigmoid	0	0.000	1.9
GTEx	Colon Transverse	0	0.000	1.8
GTEx	Esophagus Gastroesophageal Junction	0	0.000	1.8
GTEx	Esophagus Mucosa	1	0.030	1.7
GTEx	Esophagus Muscularis	1	0.031	1.7
GTEx	Heart Atrial Appendage	0	0.000	1.7
GTEx	Heart Left Ventricle	1	0.065	1.7
GTEx	Liver	0	0.000	1.8
GTEx	Lung	1	0.035	1.7
GTEx	Muscle Skeletal	0	0.000	1.8
GTEx	Nerve Tibial	1	0.023	1.7
GTEx	Ovary	0	0.000	1.8
GTEx	Pancreas	0	0.000	1.7
GTEx	Pituitary	0	0.000	1.7
GTEx	Prostate	1	0.120	1.8
GTEx	Skin Not Sun Exposed Suprapubic	2	0.081	1.8
GTEx	Skin Sun Exposed Lower leg	3	0.082	1.8
GTEx	Small Intestine Terminal Ileum	0	0.000	1.9
GTEx	Spleen	1	0.071	1.8
GTEx	Stomach	0	0.000	1.8
GTEx	Testis	0	0.000	1.8
GTEx	Thyroid	1	0.025	1.8
GTEx	Uterus	0	0.000	1.9
GTEx	Vagina	0	0.000	1.7
GTEx	Whole Blood	0	0.000	1.7
METSIM	Adipose	4	0.087	1.6
NTR	Blood	1	0.042	1.6
ROSMAP	Brain Pre-frontal Cortex	3	0.068	1.6
YFS	Blood	2	0.043	1.6
CommonMind	Brain Pre-frontal Cortex	5	0.093	1.7
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	0	0.000	1.6
The Cancer Genome Atlas	Breast Invasive Carcinoma	2	0.045	1.6
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	0	0.000	1.6
The Cancer Genome Atlas	Colon Adenocarcinoma	1	0.048	1.6
The Cancer Genome Atlas	Esophageal Carcinoma	0	0.000	1.7
The Cancer Genome Atlas	Glioblastoma Multiforme	0	0.000	1.6
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	1	0.037	1.7
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	0	0.000	1.6
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	1	0.049	1.6
The Cancer Genome Atlas	Brain Lower Grade Glioma	1	0.023	1.6
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	0	0.000	1.5
The Cancer Genome Atlas	Lung Adenocarcinoma	1	0.034	1.6
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	1	0.040	1.6
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	0	0.000	1.6
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	0	0.000	1.6
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	1	0.075	1.7
The Cancer Genome Atlas	Prostate Adenocarcinoma	0	0.000	1.6
The Cancer Genome Atlas	Rectum Adenocarcinoma	0	0.000	1.6
The Cancer Genome Atlas	Soft Tissue Sarcoma	0	0.000	1.6
The Cancer Genome Atlas	Skin Cutaneous Melanoma	0	0.000	1.6
The Cancer Genome Atlas	Stomach Adenocarcinoma	0	0.000	1.6
The Cancer Genome Atlas	Testicular Germ Cell Tumors	0	0.000	1.7
The Cancer Genome Atlas	Thyroid Carcinoma	3	0.058	1.6
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	0	0.000	1.8