Best TWAS P=3.47e-10 · Best GWAS P=3.32e-18 conditioned to 2.17e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-288H12.3 | 0.17 | 0.01 | lasso | 8 | 0.06 | 2.3e-05 | 3.0 | 5.4 | 6.8e-08 | 0.14 | 0.23 | 0.05 | TRUE |
| 2 | GTEx | Thyroid | RP11-288H12.3 | 0.14 | 0.07 | enet | 10 | 0.08 | 8.3e-07 | -3.1 | 5.4 | 5.8e-08 | 0.23 | 0.49 | 0.20 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SLC22A1 | 0.04 | 0.01 | enet | 17 | 0.01 | 5.2e-04 | 4.1 | -6.3 | 3.5e-10 | -0.59 | 0.01 | 0.94 | TRUE |